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Murcko scaffold

Ring system with 4 rings and 25 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
6
With full pages
1
Scaffold SMILES

O=C1NC(=O)C(Cc2ccc(OCc3nc4ccccc4[nH]3)cc2)S1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC(=O)C(Cc2ccc(OCc3nc4ccccc4[nH]3)cc2)S1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Rivoglitazone chemical structure, C20H19N3O4S, CAS 185428-18-6
Rivoglitazone
CAS 185428-18-6C20H19N3O4S
Rivoglitazone hydrochloride chemical structure, C20H20ClN3O4S, CAS 299176-11-7
Rivoglitazone hydrochloride
CAS 299176-11-7C20H20ClN3O4S
2,4-Thiazolidinedione, 5-((4-((1-methyl-6-(sulfooxy)-1H-benzimidazol-2-yl)methoxy)phenyl)methyl)- chemical structure, C19H17N3O7S2, CAS 332944-29-3
2,4-Thiazolidinedione, 5-((4-((1-methyl-6-(sulfooxy)-1H-benzimidazol-2-yl)methoxy)phenyl)methyl)-
CAS 332944-29-3C19H17N3O7S2
N-Demethyl rivoglitazone chemical structure, C19H17N3O4S, CAS 560131-16-0
N-Demethyl rivoglitazone
CAS 560131-16-0C19H17N3O4S
O-Demethyl rivoglitazone chemical structure, C19H17N3O4S, CAS 770698-20-9
O-Demethyl rivoglitazone
CAS 770698-20-9C19H17N3O4S
2,4-Thiazolidinedione, 5-hydroxy-5-((4-((6-methoxy-1-methyl-1H-benzimidazol-2-yl)methoxy)phenyl)methyl)- chemical structure, C20H19N3O5S, CAS 1357351-03-1
2,4-Thiazolidinedione, 5-hydroxy-5-((4-((6-methoxy-1-methyl-1H-benzimidazol-2-yl)methoxy)phenyl)methyl)-
CAS 1357351-03-1C20H19N3O5S