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Murcko scaffold

1-Phenyl-3-(2-pyridinylamino)-2-propen-1-one scaffold

10 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
10
With full pages
3
Scaffold SMILES

O=C(C=CNc1ccccn1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenyl-3-(2-pyridinylamino)-2-propen-1-one page
Murcko scaffold O=C(C=CNc1ccccn1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1-Phenyl-3-(2-pyridinylamino)-2-propen-1-one chemical structure, C14H12N2O, CAS 15753-55-6
1-Phenyl-3-(2-pyridinylamino)-2-propen-1-one
CAS 15753-55-6C14H12N2O
(E)-1-(2,4-Dimethoxyphenyl)-3-(pyridin-2-ylamino)prop-2-en-1-one chemical structure, C16H16N2O3, CAS 326877-30-9
(E)-1-(2,4-Dimethoxyphenyl)-3-(pyridin-2-ylamino)prop-2-en-1-one
CAS 326877-30-9C16H16N2O3
(E)-1-(4-Bromophenyl)-3-[(4-methylpyridin-2-yl)amino]prop-2-en-1-one chemical structure, C15H13BrN2O, CAS 369392-07-4
(E)-1-(4-Bromophenyl)-3-[(4-methylpyridin-2-yl)amino]prop-2-en-1-one
CAS 369392-07-4C15H13BrN2O
(2E)-1-(4-Methoxyphenyl)-3-[(4-methylpyridin-2-yl)amino]prop-2-en-1-one chemical structure, C16H16N2O2, CAS 333750-84-8
(2E)-1-(4-Methoxyphenyl)-3-[(4-methylpyridin-2-yl)amino]prop-2-en-1-one
CAS 333750-84-8C16H16N2O2
(2E)-1-(4-Chlorophenyl)-3-(2-pyridylamino)prop-2-en-1-one chemical structure, C14H11ClN2O, CAS 1020413-85-7
(2E)-1-(4-Chlorophenyl)-3-(2-pyridylamino)prop-2-en-1-one
CAS 1020413-85-7C14H11ClN2O
(E)-2-Benzoyl-3-(pyridin-2-ylamino)prop-2-enenitrile chemical structure, C15H11N3O, CAS 84095-81-8
(E)-2-Benzoyl-3-(pyridin-2-ylamino)prop-2-enenitrile
CAS 84095-81-8C15H11N3O
2-Propen-1-one, 1-(4-fluorophenyl)-2-methyl-3-(2-pyridinylamino)- chemical structure, C15H13FN2O, CAS 65201-25-4
2-Propen-1-one, 1-(4-fluorophenyl)-2-methyl-3-(2-pyridinylamino)-
CAS 65201-25-4C15H13FN2O
3-((5-Bromopyridin-2-yl)amino)-1-(3-(difluoromethoxy)phenyl)prop-2-en-1-one chemical structure, C15H11BrF2N2O2, CAS 828279-64-7
3-((5-Bromopyridin-2-yl)amino)-1-(3-(difluoromethoxy)phenyl)prop-2-en-1-one
CAS 828279-64-7C15H11BrF2N2O2
1-(2,4-Dichlorophenyl)-3-[(5-iodo-2-pyridinyl)amino]-2-propen-1-one chemical structure, C14H9Cl2IN2O, CAS 338401-08-4
1-(2,4-Dichlorophenyl)-3-[(5-iodo-2-pyridinyl)amino]-2-propen-1-one
CAS 338401-08-4C14H9Cl2IN2O
(Z)-3-[[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]amino]-2-(3,4-dichlorobenzoyl)prop-2-enenitrile chemical structure, C16H7Cl3F3N3O, CAS 1025666-48-1
(Z)-3-[[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]amino]-2-(3,4-dichlorobenzoyl)prop-2-enenitrile
CAS 1025666-48-1C16H7Cl3F3N3O