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Murcko scaffold

4(1H)-Pyrimidinone, tetrahydro-3-phenyl-2-thioxo- scaffold

19 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
19
With full pages
4
Scaffold SMILES

O=C1CCNC(=S)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4(1H)-Pyrimidinone, tetrahydro-3-phenyl-2-thioxo- page
Murcko scaffold O=C1CCNC(=S)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

1-Isopropyl-5-methyl-3-phenyl-2-thioxotetrahydropyrimidin-4(1H)-one chemical structure, C14H18N2OS, CAS 6625-60-1
1-Isopropyl-5-methyl-3-phenyl-2-thioxotetrahydropyrimidin-4(1H)-one
CAS 6625-60-1C14H18N2OS
4(1H)-Pyrimidinone, tetrahydro-3-phenyl-2-thioxo- chemical structure, C10H10N2OS, CAS 1203-29-8
4(1H)-Pyrimidinone, tetrahydro-3-phenyl-2-thioxo-
CAS 1203-29-8C10H10N2OS
3-(4-Methoxyphenyl)-2-sulfanylidene-1,3-diazinan-4-one chemical structure, C11H12N2O2S, CAS 5596-28-1
3-(4-Methoxyphenyl)-2-sulfanylidene-1,3-diazinan-4-one
CAS 5596-28-1C11H12N2O2S
3-(4-Propoxyphenyl)-2-sulfanylidene-1,3-diazinan-4-one chemical structure, C13H16N2O2S, CAS 5540-80-7
3-(4-Propoxyphenyl)-2-sulfanylidene-1,3-diazinan-4-one
CAS 5540-80-7C13H16N2O2S
3-(4-Propan-2-yloxyphenyl)-2-sulfanylidene-1,3-diazinan-4-one chemical structure, C13H16N2O2S, CAS 5540-78-3
3-(4-Propan-2-yloxyphenyl)-2-sulfanylidene-1,3-diazinan-4-one
CAS 5540-78-3C13H16N2O2S
3-(4-Butoxyphenyl)-2-sulfanylidene-1,3-diazinan-4-one chemical structure, C14H18N2O2S, CAS 5596-27-0
3-(4-Butoxyphenyl)-2-sulfanylidene-1,3-diazinan-4-one
CAS 5596-27-0C14H18N2O2S
3-(4-Pentoxyphenyl)-2-sulfanylidene-1,3-diazinan-4-one chemical structure, C15H20N2O2S, CAS 5540-82-9
3-(4-Pentoxyphenyl)-2-sulfanylidene-1,3-diazinan-4-one
CAS 5540-82-9C15H20N2O2S
5-Methyl-3-(4-propan-2-yloxyphenyl)-2-sulfanylidene-1,3-diazinan-4-one chemical structure, C14H18N2O2S, CAS 30695-41-1
5-Methyl-3-(4-propan-2-yloxyphenyl)-2-sulfanylidene-1,3-diazinan-4-one
CAS 30695-41-1C14H18N2O2S
5-Methyl-3-[4-(pentyloxy)phenyl]-2-sulfanylidene-1,3-diazinan-4-one chemical structure, C16H22N2O2S, CAS 29622-53-5
5-Methyl-3-[4-(pentyloxy)phenyl]-2-sulfanylidene-1,3-diazinan-4-one
CAS 29622-53-5C16H22N2O2S
5-Methyl-3-phenyl-2-sulfanylidene-1,3-diazinan-4-one chemical structure, C11H12N2OS, CAS 30695-37-5
5-Methyl-3-phenyl-2-sulfanylidene-1,3-diazinan-4-one
CAS 30695-37-5C11H12N2OS
3-(4-Ethoxyphenyl)-5-methyl-2-sulfanylidene-1,3-diazinan-4-one chemical structure, C13H16N2O2S, CAS 30695-39-7
3-(4-Ethoxyphenyl)-5-methyl-2-sulfanylidene-1,3-diazinan-4-one
CAS 30695-39-7C13H16N2O2S
3-(4-Butoxyphenyl)-5-methyl-2-sulfanylidene-1,3-diazinan-4-one chemical structure, C15H20N2O2S, CAS 30695-42-2
3-(4-Butoxyphenyl)-5-methyl-2-sulfanylidene-1,3-diazinan-4-one
CAS 30695-42-2C15H20N2O2S
5-Methyl-3-(4-propoxyphenyl)-2-sulfanylidene-1,3-diazinan-4-one chemical structure, C14H18N2O2S, CAS 30695-40-0
5-Methyl-3-(4-propoxyphenyl)-2-sulfanylidene-1,3-diazinan-4-one
CAS 30695-40-0C14H18N2O2S
3-(4-Methoxyphenyl)-5-methyl-2-sulfanylidene-1,3-diazinan-4-one chemical structure, C12H14N2O2S, CAS 30695-38-6
3-(4-Methoxyphenyl)-5-methyl-2-sulfanylidene-1,3-diazinan-4-one
CAS 30695-38-6C12H14N2O2S
3-(4-Fluorophenyl)-5-methyl-2-sulfanylidene-1,3-diazinan-4-one chemical structure, C11H11FN2OS, CAS 30695-44-4
3-(4-Fluorophenyl)-5-methyl-2-sulfanylidene-1,3-diazinan-4-one
CAS 30695-44-4C11H11FN2OS
4(1H)-Pyrimidinone, 3-(2,6-dimethylphenyl)-1-ethyltetrahydro-2-thioxo- chemical structure, C14H18N2OS, CAS 196794-62-4
4(1H)-Pyrimidinone, 3-(2,6-dimethylphenyl)-1-ethyltetrahydro-2-thioxo-
CAS 196794-62-4C14H18N2OS
4(1H)-Pyrimidinone, tetrahydro-1-methyl-3-phenyl-2-thioxo- chemical structure, C11H12N2OS, CAS 59669-78-2
4(1H)-Pyrimidinone, tetrahydro-1-methyl-3-phenyl-2-thioxo-
CAS 59669-78-2C11H12N2OS
3-Phenyl-2-sulfanylidene-5-(trifluoromethyl)tetrahydropyrimidin-4(1H)-one chemical structure, C11H9F3N2OS, CAS 90715-76-7
3-Phenyl-2-sulfanylidene-5-(trifluoromethyl)tetrahydropyrimidin-4(1H)-one
CAS 90715-76-7C11H9F3N2OS
1-Butyl-3-(4-nitrophenyl)-2-sulfanylidenetetrahydropyrimidin-4(1H)-one chemical structure, C14H17N3O3S, CAS 666180-33-2
1-Butyl-3-(4-nitrophenyl)-2-sulfanylidenetetrahydropyrimidin-4(1H)-one
CAS 666180-33-2C14H17N3O3S