CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 28 atoms

28 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
28
Chemicals
28
With full pages
27
Scaffold SMILES

O=C(NN=Cc1ccccc1OCc1ccccc1)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1OCc1ccccc1)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

2-(2-(2-(Benzyloxy)benzylidene)hydrazino)-N-(3,4-dichlorophenyl)-2-oxoacetamide chemical structure, C22H17Cl2N3O3, CAS 352562-62-0
2-(2-(2-(Benzyloxy)benzylidene)hydrazino)-N-(3,4-dichlorophenyl)-2-oxoacetamide
CAS 352562-62-0C22H17Cl2N3O3
2-(2-(2-((4-CL-Benzyl)oxy)benzylidene)hydrazino)-N-(2,3-DI-CL-PH)-2-oxoacetamide chemical structure, C22H16Cl3N3O3, CAS 765274-22-4
2-(2-(2-((4-CL-Benzyl)oxy)benzylidene)hydrazino)-N-(2,3-DI-CL-PH)-2-oxoacetamide
CAS 765274-22-4C22H16Cl3N3O3
2-((2E)-2-{2-[(4-Chlorobenzyl)oxy]benzylidene}hydrazino)-N-(3,4-dichlorophenyl)-2-oxoacetamide chemical structure, C22H16Cl3N3O3, CAS 767291-00-9
2-((2E)-2-{2-[(4-Chlorobenzyl)oxy]benzylidene}hydrazino)-N-(3,4-dichlorophenyl)-2-oxoacetamide
CAS 767291-00-9C22H16Cl3N3O3
2-(2-(2-((4-BR-Benzyl)oxy)benzylidene)hydrazino)-N-(2,5-DI-CL-PH)-2-oxoacetamide chemical structure, C22H16BrCl2N3O3, CAS 765274-37-1
2-(2-(2-((4-BR-Benzyl)oxy)benzylidene)hydrazino)-N-(2,5-DI-CL-PH)-2-oxoacetamide
CAS 765274-37-1C22H16BrCl2N3O3
2-(2-(2-((4-Bromobenzyl)oxy)benzylidene)hydrazino)-2-oxo-N-phenylacetamide chemical structure, C22H18BrN3O3, CAS 356097-35-3
2-(2-(2-((4-Bromobenzyl)oxy)benzylidene)hydrazino)-2-oxo-N-phenylacetamide
CAS 356097-35-3C22H18BrN3O3
2-(2-(2-((4-BR-Benzyl)oxy)benzylidene)hydrazino)-N-(2,3-DI-CL-PH)-2-oxoacetamide chemical structure, C22H16BrCl2N3O3, CAS 765274-24-6
2-(2-(2-((4-BR-Benzyl)oxy)benzylidene)hydrazino)-N-(2,3-DI-CL-PH)-2-oxoacetamide
CAS 765274-24-6C22H16BrCl2N3O3
2-(2-(2-((4-BR-Benzyl)oxy)benzylidene)hydrazino)-N-(3,4-DI-CL-PH)-2-oxoacetamide chemical structure, C22H16BrCl2N3O3, CAS 765296-69-3
2-(2-(2-((4-BR-Benzyl)oxy)benzylidene)hydrazino)-N-(3,4-DI-CL-PH)-2-oxoacetamide
CAS 765296-69-3C22H16BrCl2N3O3
2-(2-(2-(Benzyloxy)benzylidene)hydrazino)-N-(4-ethylphenyl)-2-oxoacetamide chemical structure, C24H23N3O3, CAS 881445-75-6
2-(2-(2-(Benzyloxy)benzylidene)hydrazino)-N-(4-ethylphenyl)-2-oxoacetamide
CAS 881445-75-6C24H23N3O3
Methyl 4-((2-(2-((4-ethylanilino)(oxo)acetyl)carbohydrazonoyl)phenoxy)methyl)benzoate chemical structure, C26H25N3O5, CAS 881450-69-7
Methyl 4-((2-(2-((4-ethylanilino)(oxo)acetyl)carbohydrazonoyl)phenoxy)methyl)benzoate
CAS 881450-69-7C26H25N3O5
2-(2-(2-((4-Chlorobenzyl)oxy)benzylidene)hydrazino)-N-(4-methylphenyl)-2-oxoacetamide chemical structure, C23H20ClN3O3, CAS 881454-26-8
2-(2-(2-((4-Chlorobenzyl)oxy)benzylidene)hydrazino)-N-(4-methylphenyl)-2-oxoacetamide
CAS 881454-26-8C23H20ClN3O3
2-(2-(2-(Benzyloxy)-5-BR-benzylidene)hydrazino)-N-(4-ethylphenyl)-2-oxoacetamide chemical structure, C24H22BrN3O3, CAS 880057-46-5
2-(2-(2-(Benzyloxy)-5-BR-benzylidene)hydrazino)-N-(4-ethylphenyl)-2-oxoacetamide
CAS 880057-46-5C24H22BrN3O3
2-(2-(2-(Benzyloxy)benzylidene)hydrazino)-N-(3-methoxyphenyl)-2-oxoacetamide chemical structure, C23H21N3O4, CAS 357412-72-7
2-(2-(2-(Benzyloxy)benzylidene)hydrazino)-N-(3-methoxyphenyl)-2-oxoacetamide
CAS 357412-72-7C23H21N3O4
Methyl 4-((2-(2-(anilino(oxo)acetyl)carbohydrazonoyl)phenoxy)methyl)benzoate chemical structure, C24H21N3O5, CAS 880075-33-2
Methyl 4-((2-(2-(anilino(oxo)acetyl)carbohydrazonoyl)phenoxy)methyl)benzoate
CAS 880075-33-2C24H21N3O5
2-(2-(2-(Benzyloxy)-5-BR-benzylidene)hydrazino)-N-(4-methylphenyl)-2-oxoacetamide chemical structure, C23H20BrN3O3, CAS 880073-80-3
2-(2-(2-(Benzyloxy)-5-BR-benzylidene)hydrazino)-N-(4-methylphenyl)-2-oxoacetamide
CAS 880073-80-3C23H20BrN3O3
2-(2-(2-((4-CL-Benzyl)oxy)benzylidene)hydrazino)-N-(4-ethyl-PH)-2-oxoacetamide chemical structure, C24H22ClN3O3, CAS 881840-07-9
2-(2-(2-((4-CL-Benzyl)oxy)benzylidene)hydrazino)-N-(4-ethyl-PH)-2-oxoacetamide
CAS 881840-07-9C24H22ClN3O3
Methyl 4-((2-(2-(oxo(4-toluidino)acetyl)carbohydrazonoyl)phenoxy)methyl)benzoate chemical structure, C25H23N3O5, CAS 881840-16-0
Methyl 4-((2-(2-(oxo(4-toluidino)acetyl)carbohydrazonoyl)phenoxy)methyl)benzoate
CAS 881840-16-0C25H23N3O5
2-(2-(2-(Benzyloxy)benzylidene)hydrazino)-2-oxo-N-phenylacetamide chemical structure, C22H19N3O3, CAS 357411-91-7
2-(2-(2-(Benzyloxy)benzylidene)hydrazino)-2-oxo-N-phenylacetamide
CAS 357411-91-7C22H19N3O3
2-(2-(2-(Benzyloxy)-5-BR-benzylidene)hydrazino)-N-(3-meo-phenyl)-2-oxoacetamide chemical structure, C23H20BrN3O4, CAS 881467-26-1
2-(2-(2-(Benzyloxy)-5-BR-benzylidene)hydrazino)-N-(3-meo-phenyl)-2-oxoacetamide
CAS 881467-26-1C23H20BrN3O4
2-(2-(2-(Benzyloxy)-5-bromobenzylidene)hydrazino)-2-oxo-N-phenylacetamide chemical structure, C22H18BrN3O3, CAS 881458-62-4
2-(2-(2-(Benzyloxy)-5-bromobenzylidene)hydrazino)-2-oxo-N-phenylacetamide
CAS 881458-62-4C22H18BrN3O3
2-(2-(2-((4-Bromobenzyl)oxy)benzylidene)hydrazino)-N-(4-methoxyphenyl)-2-oxoacetamide chemical structure, C23H20BrN3O4, CAS 881470-02-6
2-(2-(2-((4-Bromobenzyl)oxy)benzylidene)hydrazino)-N-(4-methoxyphenyl)-2-oxoacetamide
CAS 881470-02-6C23H20BrN3O4
Methyl 4-((2-(2-((3-methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenoxy)methyl)benzoate chemical structure, C25H23N3O6, CAS 881470-43-5
Methyl 4-((2-(2-((3-methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenoxy)methyl)benzoate
CAS 881470-43-5C25H23N3O6
2-(2-(2-((4-BR-Benzyl)oxy)benzylidene)hydrazino)-N-(3-meo-phenyl)-2-oxoacetamide chemical structure, C23H20BrN3O4, CAS 881449-87-2
2-(2-(2-((4-BR-Benzyl)oxy)benzylidene)hydrazino)-N-(3-meo-phenyl)-2-oxoacetamide
CAS 881449-87-2C23H20BrN3O4
Methyl 4-((2-(2-((4-methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenoxy)methyl)benzoate chemical structure, C25H23N3O6, CAS 881402-59-1
Methyl 4-((2-(2-((4-methoxyanilino)(oxo)acetyl)carbohydrazonoyl)phenoxy)methyl)benzoate
CAS 881402-59-1C25H23N3O6
2-(2-(2-(Benzyloxy)-5-bromobenzylidene)hydrazino)-N-(3,4-dichlorophenyl)-2-oxoacetamide chemical structure, C22H16BrCl2N3O3, CAS 881403-29-8
2-(2-(2-(Benzyloxy)-5-bromobenzylidene)hydrazino)-N-(3,4-dichlorophenyl)-2-oxoacetamide
CAS 881403-29-8C22H16BrCl2N3O3