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Murcko scaffold

Ring system with 3 rings and 27 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
13
With full pages
11
Scaffold SMILES

O=C(COc1ccccc1)NN=Cc1ccccc1OCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)NN=Cc1ccccc1OCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

N'-{2-[(3-Bromobenzyl)oxy]-5-methoxybenzylidene}-2-(4-chlorophenoxy)acetohydrazide chemical structure, C23H20BrClN2O4, CAS 339220-04-1
N'-{2-[(3-Bromobenzyl)oxy]-5-methoxybenzylidene}-2-(4-chlorophenoxy)acetohydrazide
CAS 339220-04-1C23H20BrClN2O4
N'-(2-(Benzyloxy)benzylidene)-2-(2-chlorophenoxy)acetohydrazide chemical structure, C22H19ClN2O3, CAS 477730-76-0
N'-(2-(Benzyloxy)benzylidene)-2-(2-chlorophenoxy)acetohydrazide
CAS 477730-76-0C22H19ClN2O3
N'-(2-(Benzyloxy)benzylidene)-2-(2-methoxyphenoxy)acetohydrazide chemical structure, C23H22N2O4, CAS 302910-42-5
N'-(2-(Benzyloxy)benzylidene)-2-(2-methoxyphenoxy)acetohydrazide
CAS 302910-42-5C23H22N2O4
N'-((E)-{2-[(4-Bromobenzyl)oxy]phenyl}methylidene)-2-(2,3-dichlorophenoxy)acetohydrazide chemical structure, C22H17BrCl2N2O3, CAS 477730-89-5
N'-((E)-{2-[(4-Bromobenzyl)oxy]phenyl}methylidene)-2-(2,3-dichlorophenoxy)acetohydrazide
CAS 477730-89-5C22H17BrCl2N2O3
N'-(2-(Benzyloxy)benzylidene)-2-(4-methylphenoxy)acetohydrazide chemical structure, C23H22N2O3, CAS 302910-08-3
N'-(2-(Benzyloxy)benzylidene)-2-(4-methylphenoxy)acetohydrazide
CAS 302910-08-3C23H22N2O3
N'-(2-(Benzyloxy)benzylidene)-2-(3-methylphenoxy)acetohydrazide chemical structure, C23H22N2O3, CAS 303083-77-4
N'-(2-(Benzyloxy)benzylidene)-2-(3-methylphenoxy)acetohydrazide
CAS 303083-77-4C23H22N2O3
N'-(2-(Benzyloxy)benzylidene)-2-(5-isopropyl-2-methylphenoxy)acetohydrazide chemical structure, C26H28N2O3, CAS 302910-05-0
N'-(2-(Benzyloxy)benzylidene)-2-(5-isopropyl-2-methylphenoxy)acetohydrazide
CAS 302910-05-0C26H28N2O3
N'-(2-(Benzyloxy)benzylidene)-2-(4-nitrophenoxy)acetohydrazide chemical structure, C22H19N3O5, CAS 303085-04-3
N'-(2-(Benzyloxy)benzylidene)-2-(4-nitrophenoxy)acetohydrazide
CAS 303085-04-3C22H19N3O5
N'-(2-(Benzyloxy)benzylidene)-2-(2-methylphenoxy)acetohydrazide chemical structure, C23H22N2O3, CAS 303083-82-1
N'-(2-(Benzyloxy)benzylidene)-2-(2-methylphenoxy)acetohydrazide
CAS 303083-82-1C23H22N2O3
N'-(2-(Benzyloxy)benzylidene)-2-(2-isopropyl-5-methylphenoxy)acetohydrazide chemical structure, C26H28N2O3, CAS 302910-11-8
N'-(2-(Benzyloxy)benzylidene)-2-(2-isopropyl-5-methylphenoxy)acetohydrazide
CAS 302910-11-8C26H28N2O3
N'-(2-((4-Chlorobenzyl)oxy)benzylidene)-2-(2-chlorophenoxy)acetohydrazide chemical structure, C22H18Cl2N2O3, CAS 444561-59-5
N'-(2-((4-Chlorobenzyl)oxy)benzylidene)-2-(2-chlorophenoxy)acetohydrazide
CAS 444561-59-5C22H18Cl2N2O3
Methyl 4-((2-(2-((2,3-dichlorophenoxy)acetyl)carbohydrazonoyl)phenoxy)methyl)benzoate chemical structure, C24H20Cl2N2O5, CAS 881402-98-8
Methyl 4-((2-(2-((2,3-dichlorophenoxy)acetyl)carbohydrazonoyl)phenoxy)methyl)benzoate
CAS 881402-98-8C24H20Cl2N2O5
N'-(2-(Benzyloxy)-5-bromobenzylidene)-2-(2,3-dichlorophenoxy)acetohydrazide chemical structure, C22H17BrCl2N2O3, CAS 881403-04-9
N'-(2-(Benzyloxy)-5-bromobenzylidene)-2-(2,3-dichlorophenoxy)acetohydrazide
CAS 881403-04-9C22H17BrCl2N2O3