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Murcko scaffold

2-Oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide scaffold

56 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
56
With full pages
29
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc[nH]c1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide page
Murcko scaffold O=C(Nc1ccccc1)c1ccc[nH]c1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 56 chemicals

Isonixin chemical structure, C14H14N2O2, CAS 57021-61-1
Isonixin
CAS 57021-61-1C14H14N2O2
1-Allyl-N-(4-methoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C16H16N2O3, CAS 320419-74-7
1-Allyl-N-(4-methoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 320419-74-7C16H16N2O3
1-Allyl-N-(2,4-dimethoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C17H18N2O4, CAS 320419-79-2
1-Allyl-N-(2,4-dimethoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 320419-79-2C17H18N2O4
1-Allyl-N-(3,5-dimethoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C17H18N2O4, CAS 320419-80-5
1-Allyl-N-(3,5-dimethoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 320419-80-5C17H18N2O4
1-Allyl-2-oxo-N-(3,4,5-trimethoxyphenyl)-1,2-dihydro-3-pyridinecarboxamide chemical structure, C18H20N2O5, CAS 320419-86-1
1-Allyl-2-oxo-N-(3,4,5-trimethoxyphenyl)-1,2-dihydro-3-pyridinecarboxamide
CAS 320419-86-1C18H20N2O5
1-Allyl-N-(2,5-dimethoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C17H18N2O4, CAS 320419-87-2
1-Allyl-N-(2,5-dimethoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 320419-87-2C17H18N2O4
1-Allyl-N-(3,4-dimethoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C17H18N2O4, CAS 320419-90-7
1-Allyl-N-(3,4-dimethoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 320419-90-7C17H18N2O4
1-Allyl-N-(4-ethoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C17H18N2O3, CAS 339027-26-8
1-Allyl-N-(4-ethoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 339027-26-8C17H18N2O3
1-Allyl-N-(4-fluorophenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C15H13FN2O2, CAS 339027-29-1
1-Allyl-N-(4-fluorophenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 339027-29-1C15H13FN2O2
1-Allyl-N-(4-methylphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C16H16N2O2, CAS 339027-31-5
1-Allyl-N-(4-methylphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 339027-31-5C16H16N2O2
1-Allyl-N-(4-chlorophenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C15H13ClN2O2, CAS 339027-35-9
1-Allyl-N-(4-chlorophenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 339027-35-9C15H13ClN2O2
1-Allyl-N-(3-chloro-4-methoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C16H15ClN2O3, CAS 339027-38-2
1-Allyl-N-(3-chloro-4-methoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 339027-38-2C16H15ClN2O3
1-Allyl-N-(3-chloro-4-methylphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C16H15ClN2O2, CAS 339027-40-6
1-Allyl-N-(3-chloro-4-methylphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 339027-40-6C16H15ClN2O2
1-Allyl-N-(3,4-dimethylphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C17H18N2O2, CAS 339027-43-9
1-Allyl-N-(3,4-dimethylphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 339027-43-9C17H18N2O2
1-Allyl-N-[4-(methylsulfanyl)phenyl]-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C16H16N2O2S, CAS 339027-45-1
1-Allyl-N-[4-(methylsulfanyl)phenyl]-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 339027-45-1C16H16N2O2S
1-Allyl-N-(3,4-dichlorophenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C15H12Cl2N2O2, CAS 339027-47-3
1-Allyl-N-(3,4-dichlorophenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 339027-47-3C15H12Cl2N2O2
1-Allyl-N-[4-(dimethylamino)phenyl]-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C17H19N3O2, CAS 339027-50-8
1-Allyl-N-[4-(dimethylamino)phenyl]-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 339027-50-8C17H19N3O2
N-[4-(Acetylamino)phenyl]-1-allyl-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C17H17N3O3, CAS 339027-53-1
N-[4-(Acetylamino)phenyl]-1-allyl-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 339027-53-1C17H17N3O3
N-(4-Methoxyphenyl)-2-oxo-1-propylpyridine-3-carboxamide chemical structure, C16H18N2O3, CAS 339027-97-3
N-(4-Methoxyphenyl)-2-oxo-1-propylpyridine-3-carboxamide
CAS 339027-97-3C16H18N2O3
N-(4-Methoxyphenyl)-1-(3-methyl-2-butenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C18H20N2O3, CAS 339028-20-5
N-(4-Methoxyphenyl)-1-(3-methyl-2-butenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 339028-20-5C18H20N2O3
N-(4-Methoxyphenyl)-2-oxo-1-(2-propynyl)-1,2-dihydro-3-pyridinecarboxamide chemical structure, C16H14N2O3, CAS 339028-30-7
N-(4-Methoxyphenyl)-2-oxo-1-(2-propynyl)-1,2-dihydro-3-pyridinecarboxamide
CAS 339028-30-7C16H14N2O3
1-(3,3-Dichloro-2-propenyl)-N-(4-methoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C16H14Cl2N2O3, CAS 400087-61-8
1-(3,3-Dichloro-2-propenyl)-N-(4-methoxyphenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 400087-61-8C16H14Cl2N2O3
Ethyl 2-[3-(anilinocarbonyl)-5-chloro-2-oxo-1(2H)-pyridinyl]acetate chemical structure, C16H15ClN2O4, CAS 339028-37-4
Ethyl 2-[3-(anilinocarbonyl)-5-chloro-2-oxo-1(2H)-pyridinyl]acetate
CAS 339028-37-4C16H15ClN2O4
5-Chloro-2-oxo-N-phenyl-1-(2-propynyl)-1,2-dihydro-3-pyridinecarboxamide chemical structure, C15H11ClN2O2, CAS 339028-41-0
5-Chloro-2-oxo-N-phenyl-1-(2-propynyl)-1,2-dihydro-3-pyridinecarboxamide
CAS 339028-41-0C15H11ClN2O2