Murcko scaffold
Ring system with 4 rings and 27 atoms
37 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 27
- Chemicals
- 37
- With full pages
- 10
Scaffold SMILES
O=C(Nc1ccc(NC(=O)c2cc3ccccc3o2)cc1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 37 of 37 chemicals
![N-[4-[(2-Bromobenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide chemical structure, C23H17BrN2O4, CAS 425618-10-6](/s/LIIINLOHQOVVIB-UHFFFAOYSA-N.svg)
N-[4-[(2-Bromobenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide
CAS 425618-10-6C23H17BrN2O4
![N-[4-[(4-Bromobenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide chemical structure, C23H17BrN2O4, CAS 445410-15-1](/s/QXIXDMVTJWWTES-UHFFFAOYSA-N.svg)
N-[4-[(4-Bromobenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide
CAS 445410-15-1C23H17BrN2O4
![N-[4-[(4-Ethoxybenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide chemical structure, C25H22N2O5, CAS 425611-98-9](/s/DBBGWPVZJQRDON-UHFFFAOYSA-N.svg)
N-[4-[(4-Ethoxybenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide
CAS 425611-98-9C25H22N2O5
![N-{4-[(4-Isopropoxybenzoyl)amino]-2-methoxyphenyl}-1-benzofuran-2-carboxamide chemical structure, C26H24N2O5, CAS 445410-17-3](/s/YCNRXPOHBYTGHA-UHFFFAOYSA-N.svg)
N-{4-[(4-Isopropoxybenzoyl)amino]-2-methoxyphenyl}-1-benzofuran-2-carboxamide
CAS 445410-17-3C26H24N2O5
![N-[4-[(2,6-Dimethoxybenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide chemical structure, C25H22N2O6, CAS 702647-49-2](/s/YBJAQPIASAVAMW-UHFFFAOYSA-N.svg)
N-[4-[(2,6-Dimethoxybenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide
CAS 702647-49-2C25H22N2O6
![N-[4-[(3-Methylbenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide chemical structure, C23H18N2O3, CAS 333355-21-8](/s/QOIUGYMDKQZPMT-UHFFFAOYSA-N.svg)
N-[4-[(3-Methylbenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide
CAS 333355-21-8C23H18N2O3
![N-[4-[(4-Fluorobenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide chemical structure, C23H17FN2O4, CAS 425625-51-0](/s/NVEYUFXDLVQFBL-UHFFFAOYSA-N.svg)
N-[4-[(4-Fluorobenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide
CAS 425625-51-0C23H17FN2O4
![N-[4-[(2-Fluorobenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide chemical structure, C23H17FN2O4, CAS 347317-65-1](/s/KTZWEMWLWVEZTN-UHFFFAOYSA-N.svg)
N-[4-[(2-Fluorobenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide
CAS 347317-65-1C23H17FN2O4
![N-[2-Methyl-4-[(3,4,5-trimethoxybenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide chemical structure, C26H24N2O6, CAS 832107-16-1](/s/IKIYZKKGCCPHIH-UHFFFAOYSA-N.svg)
N-[2-Methyl-4-[(3,4,5-trimethoxybenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide
CAS 832107-16-1C26H24N2O6
![N-{4-[(3,5-Dimethoxybenzoyl)amino]-2-methylphenyl}-1-benzofuran-2-carboxamide chemical structure, C25H22N2O5, CAS 833431-44-0](/s/SPPHFGUGJFDKPV-UHFFFAOYSA-N.svg)
N-{4-[(3,5-Dimethoxybenzoyl)amino]-2-methylphenyl}-1-benzofuran-2-carboxamide
CAS 833431-44-0C25H22N2O5
![N-[2-Methoxy-4-[(2-methoxy-3-methylbenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide chemical structure, C25H22N2O5, CAS 836662-27-2](/s/CXNJTBARFYCCGJ-UHFFFAOYSA-N.svg)
N-[2-Methoxy-4-[(2-methoxy-3-methylbenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide
CAS 836662-27-2C25H22N2O5
![N-[4-[(2-Bromobenzoyl)amino]-2-methylphenyl]-1-benzofuran-2-carboxamide chemical structure, C23H17BrN2O3, CAS 446039-92-5](/s/PFEKJDVLXBQLPH-UHFFFAOYSA-N.svg)
N-[4-[(2-Bromobenzoyl)amino]-2-methylphenyl]-1-benzofuran-2-carboxamide
CAS 446039-92-5C23H17BrN2O3
![N-[4-[(4-Methoxybenzoyl)amino]-2-methylphenyl]-1-benzofuran-2-carboxamide chemical structure, C24H20N2O4, CAS 446257-89-2](/s/DTYFPZQDLXOSGE-UHFFFAOYSA-N.svg)
N-[4-[(4-Methoxybenzoyl)amino]-2-methylphenyl]-1-benzofuran-2-carboxamide
CAS 446257-89-2C24H20N2O4
![N-[4-[(5-Chloro-2-methoxybenzoyl)amino]-2-methylphenyl]-1-benzofuran-2-carboxamide chemical structure, C24H19ClN2O4, CAS 462064-03-5](/s/NQVBSOFQOMVVGX-UHFFFAOYSA-N.svg)
N-[4-[(5-Chloro-2-methoxybenzoyl)amino]-2-methylphenyl]-1-benzofuran-2-carboxamide
CAS 462064-03-5C24H19ClN2O4
![N-[4-[(3-Chloro-4-methylbenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide chemical structure, C24H19ClN2O4, CAS 432020-89-8](/s/YBKHWGOCKKNJGP-UHFFFAOYSA-N.svg)
N-[4-[(3-Chloro-4-methylbenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide
CAS 432020-89-8C24H19ClN2O4
![N-[4-[(4-Chlorobenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide chemical structure, C23H17ClN2O4, CAS 380866-61-5](/s/IMHUTDHTVSFSIG-UHFFFAOYSA-N.svg)
N-[4-[(4-Chlorobenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide
CAS 380866-61-5C23H17ClN2O4
![N-[4-[(5-Chloro-2-methoxybenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide chemical structure, C24H19ClN2O5, CAS 401607-99-6](/s/ZVPSZQHJCXYRAD-UHFFFAOYSA-N.svg)
N-[4-[(5-Chloro-2-methoxybenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide
CAS 401607-99-6C24H19ClN2O5
![N-(2-Methoxy-4-{[(4-propoxyphenyl)carbonyl]amino}phenyl)-1-benzofuran-2-carboxamide chemical structure, C26H24N2O5, CAS 445410-16-2](/s/ODKVGGUMVDQZJO-UHFFFAOYSA-N.svg)
N-(2-Methoxy-4-{[(4-propoxyphenyl)carbonyl]amino}phenyl)-1-benzofuran-2-carboxamide
CAS 445410-16-2C26H24N2O5
![N-[4-[(3-Butoxybenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide chemical structure, C27H26N2O5, CAS 347340-07-2](/s/JKYDXDJPZHEILM-UHFFFAOYSA-N.svg)
N-[4-[(3-Butoxybenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide
CAS 347340-07-2C27H26N2O5
![N-[4-[(3-Bromo-4-ethoxybenzoyl)amino]-2-methylphenyl]-1-benzofuran-2-carboxamide chemical structure, C25H21BrN2O4, CAS 445439-31-6](/s/XDYQIXJVBNEMFK-UHFFFAOYSA-N.svg)
N-[4-[(3-Bromo-4-ethoxybenzoyl)amino]-2-methylphenyl]-1-benzofuran-2-carboxamide
CAS 445439-31-6C25H21BrN2O4
![N-[4-[(5-Bromo-2-methoxy-3-methylbenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide chemical structure, C25H21BrN2O5, CAS 708290-60-2](/s/LKEXFEJWFFNRJH-UHFFFAOYSA-N.svg)
N-[4-[(5-Bromo-2-methoxy-3-methylbenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide
CAS 708290-60-2C25H21BrN2O5
![N-[4-[(3-Bromo-4-methoxybenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide chemical structure, C23H17BrN2O4, CAS 832122-72-2](/s/KULDTOGNGIOLPD-UHFFFAOYSA-N.svg)
N-[4-[(3-Bromo-4-methoxybenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide
CAS 832122-72-2C23H17BrN2O4
![N-[4-[(5-Bromo-2-chlorobenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide chemical structure, C22H14BrClN2O3, CAS 765926-72-5](/s/YTTQIQWNUOYBID-UHFFFAOYSA-N.svg)
N-[4-[(5-Bromo-2-chlorobenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide
CAS 765926-72-5C22H14BrClN2O3
![N-[4-[(2,5-Dichlorobenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide chemical structure, C22H14Cl2N2O3, CAS 833435-64-6](/s/NFIFZGKQTKSKSL-UHFFFAOYSA-N.svg)
N-[4-[(2,5-Dichlorobenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide
CAS 833435-64-6C22H14Cl2N2O3
- N-[4-[(4-Cyano-2-fluorobenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide833440-77-0C24H16FN3O4
- N-{4-[(4-Propoxybenzoyl)amino]phenyl}-1-benzofuran-2-carboxamide835892-84-7C25H22N2O4
- N-[4-[(3-Chloro-4-methoxybenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide838616-98-1C23H17ClN2O4
- N-[4-[(3-Chlorobenzoyl)amino]-2-methoxyphenyl]-1-benzofuran-2-carboxamide425418-98-0C23H17ClN2O4
- N-{4-[(4-Ethylbenzoyl)amino]-2-methoxyphenyl}-1-benzofuran-2-carboxamide838265-36-4C25H22N2O4
- N-[4-[(3,4-Dimethoxybenzoyl)amino]-2-methylphenyl]-1-benzofuran-2-carboxamide876884-64-9C25H22N2O5
- N-[2-Methyl-4-[(2-nitrobenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide461656-75-7C23H17N3O5
- N-[2-Methoxy-4-[(3-nitrobenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide353761-60-1C23H17N3O6
- N-[2-Methoxy-4-[(4-nitrobenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide347310-87-6C23H17N3O6
- N-[2-Methoxy-4-[(2-nitrobenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide353761-59-8C23H17N3O6
- N-[2-Methyl-4-[(3-methyl-4-nitrobenzoyl)amino]phenyl]-1-benzofuran-2-carboxamide833438-33-8C24H19N3O5
- N-{4-[(2,3-Dichlorobenzoyl)amino]-2-methylphenyl}-1-benzofuran-2-carboxamide446870-30-0C23H16Cl2N2O3
- N-{4-[(3-Bromobenzoyl)amino]-2-methylphenyl}-1-benzofuran-2-carboxamide461657-23-8C23H17BrN2O3
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)c1cc2ccccc2o16 chemicals
O=C(Oc1ccc(CCN2Cc3ccccc3C2=O)cc1)c1ccccc14 chemicals
O=C(Nc1cc2c(s1)CNCC2)c1ccc(S(=O)(=O)Nc2ccccc2)cc14 chemicals
O=C(Nc1ccc(C=Cc2nc3ccccc3o2)cc1)c1ccccc13 chemicals
O=C(Nc1ccc(NC(=O)c2cc3ccccc3o2)cc1)c1cccnc12 chemicals
O=C(Nc1ccc(S(=O)(=O)Nc2ccncn2)cc1)c1cc2ccccc2o12 chemicals
O=C(Nc1cc2c(s1)CCCC2)c1ccc(NS(=O)(=O)c2ccccc2)cc11 chemical
O=C(Nc1nc2ccccc2s1)c1ccc(S(=O)(=O)NC2CCCCC2)cc11 chemical
O=S(=O)(Nc1nc2ccccc2s1)c1ccc(NCc2ccccc2)cc11 chemical
O=C(Nc1ccc(S(=O)(=O)NC2CCNCC2)cc1)c1cc2ccccc2o11 chemical
O=S(=O)(Nc1nc2ccccc2o1)c1ccc(NCc2ccccc2)cc11 chemical
O=C(Nc1cc2c(s1)CNCC2)c1ccc(S(=O)(=O)NC2CCCCC2)cc11 chemical