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Murcko scaffold

N-[4-(Pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide scaffold

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
13
With full pages
6
Scaffold SMILES

O=C(Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)c1cc2ccccc2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-[4-(Pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide page
Murcko scaffold O=C(Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)c1cc2ccccc2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

5-Fluoro-3-methyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-1-benzofuran-2-carboxamide chemical structure, C21H17FN4O4S, CAS 724741-40-6
5-Fluoro-3-methyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-1-benzofuran-2-carboxamide
CAS 724741-40-6C21H17FN4O4S
5-Fluoro-3-methyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide chemical structure, C20H15FN4O4S, CAS 724741-43-9
5-Fluoro-3-methyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide
CAS 724741-43-9C20H15FN4O4S
5-Chloro-3,6-dimethyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide chemical structure, C21H17ClN4O4S, CAS 724741-46-2
5-Chloro-3,6-dimethyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide
CAS 724741-46-2C21H17ClN4O4S
5-Chloro-3,6-dimethyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-1-benzofuran-2-carboxamide chemical structure, C22H19ClN4O4S, CAS 724741-47-3
5-Chloro-3,6-dimethyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-1-benzofuran-2-carboxamide
CAS 724741-47-3C22H19ClN4O4S
5-Ethyl-3-methyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-1-benzofuran-2-carboxamide chemical structure, C23H22N4O4S, CAS 724741-49-5
5-Ethyl-3-methyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-1-benzofuran-2-carboxamide
CAS 724741-49-5C23H22N4O4S
5-Chloro-3-methyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide chemical structure, C20H15ClN4O4S, CAS 724741-59-7
5-Chloro-3-methyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide
CAS 724741-59-7C20H15ClN4O4S
N-[4-(Pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide chemical structure, C19H14N4O4S, CAS 307540-42-7
N-[4-(Pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide
CAS 307540-42-7C19H14N4O4S
3-Methyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide chemical structure, C20H16N4O4S, CAS 380873-38-1
3-Methyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide
CAS 380873-38-1C20H16N4O4S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3-methyl-1-benzofuran-2-carboxamide chemical structure, C22H20N4O4S, CAS 381192-06-9
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3-methyl-1-benzofuran-2-carboxamide
CAS 381192-06-9C22H20N4O4S
3,6-Dimethyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide chemical structure, C21H18N4O4S, CAS 823827-48-1
3,6-Dimethyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide
CAS 823827-48-1C21H18N4O4S
3,5-Dimethyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide chemical structure, C21H18N4O4S, CAS 620585-33-3
3,5-Dimethyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-1-benzofuran-2-carboxamide
CAS 620585-33-3C21H18N4O4S
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3,5,6-trimethyl-1-benzofuran-2-carboxamide chemical structure, C24H24N4O4S, CAS 622349-62-6
N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3,5,6-trimethyl-1-benzofuran-2-carboxamide
CAS 622349-62-6C24H24N4O4S
3,5,6-Trimethyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-1-benzofuran-2-carboxamide chemical structure, C23H22N4O4S, CAS 622350-07-6
3,5,6-Trimethyl-N-{4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl}-1-benzofuran-2-carboxamide
CAS 622350-07-6C23H22N4O4S