CompoundList
Sign in
Murcko scaffold

Ring system with 5 rings and 29 atoms

6 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
29
Chemicals
6
With full pages
2
Scaffold SMILES

O=c1ccc2cnc(Nc3ccc(N4CCNCC4)cc3)nc2n1C1CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccc2cnc(Nc3ccc(N4CCNCC4)cc3)nc2n1C1CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

8-Cyclopentyl-6-acetyl-5-methyl-2-((4-(piperazin-1-yl)phenyl)amino)-7H,8H-pyrido(2,3-d)pyrimidin-7-one chemical structure, C25H30N6O2, CAS 850848-40-7
8-Cyclopentyl-6-acetyl-5-methyl-2-((4-(piperazin-1-yl)phenyl)amino)-7H,8H-pyrido(2,3-d)pyrimidin-7-one
CAS 850848-40-7C25H30N6O2
tert-Butyl 4-[4-[(6-bromo-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]phenyl]piperazine-1-carboxylate chemical structure, C28H35BrN6O3, CAS 362656-71-1
tert-Butyl 4-[4-[(6-bromo-8-cyclopentyl-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]phenyl]piperazine-1-carboxylate
CAS 362656-71-1C28H35BrN6O3
1,1-Dimethylethyl 4-[4-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]phenyl]-1-piperazinecarboxylate chemical structure, C30H38N6O4, CAS 850628-99-8
1,1-Dimethylethyl 4-[4-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]phenyl]-1-piperazinecarboxylate
CAS 850628-99-8C30H38N6O4
Narazaciclib chemical structure, C24H27N7O, CAS 1357470-29-1
Narazaciclib
CAS 1357470-29-1C24H27N7O
8-Cyclopentyl-2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile, 2-hydroxypropanoic acid chemical structure, C27H33N7O4, CAS 2928469-56-9
8-Cyclopentyl-2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxopyrido[2,3-d]pyrimidine-6-carbonitrile, 2-hydroxypropanoic acid
CAS 2928469-56-9C27H33N7O4
Desmethyl narazaciclib chemical structure, C23H25N7O, CAS 2419274-38-5
Desmethyl narazaciclib
CAS 2419274-38-5C23H25N7O