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Murcko scaffold

Ring system with 3 rings and 23 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
10
With full pages
6
Scaffold SMILES

O=C(Cc1ccccc1)NC(CN1CCCC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)NC(CN1CCCC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

ICI-204448 (free acid) chemical structure, C23H26Cl2N2O4, CAS 125190-72-9
ICI-204448 (free acid)
CAS 125190-72-9C23H26Cl2N2O4
2-(3,4-Dichlorophenyl)-N-methyl-N-(1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl)acetamide chemical structure, C22H23Cl2N3OS, CAS 155512-49-5
2-(3,4-Dichlorophenyl)-N-methyl-N-(1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl)acetamide
CAS 155512-49-5C22H23Cl2N3OS
2-(3-(1-((2-(3,4-Dichlorophenyl)acetyl)methylamino)-2-(1-pyrrolidinyl)ethyl)phenoxy)acetic acid hydrochloride (1:1) chemical structure, C23H27Cl3N2O4, CAS 121264-04-8
2-(3-(1-((2-(3,4-Dichlorophenyl)acetyl)methylamino)-2-(1-pyrrolidinyl)ethyl)phenoxy)acetic acid hydrochloride (1:1)
CAS 121264-04-8C23H27Cl3N2O4
N-Methyl-N-(1-phenyl-2-(1-pyrrolidinyl)ethyl)phenylacetamide chemical structure, C21H26N2O, CAS 157947-87-0
N-Methyl-N-(1-phenyl-2-(1-pyrrolidinyl)ethyl)phenylacetamide
CAS 157947-87-0C21H26N2O
Emd 60400 chemical structure, C21H27N3O2, CAS 142773-98-6
Emd 60400
CAS 142773-98-6C21H27N3O2
Benzeneacetamide, 3,4-dichloro-N-methyl-N-((1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl)-, hydrochloride (1:1) chemical structure, C21H25Cl3N2O, CAS 115199-84-3
Benzeneacetamide, 3,4-dichloro-N-methyl-N-((1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl)-, hydrochloride (1:1)
CAS 115199-84-3C21H25Cl3N2O
2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide chemical structure, C21H24Cl2N2O, CAS 116508-24-8
2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
CAS 116508-24-8C21H24Cl2N2O
Ici 204879 chemical structure, C23H29Cl3N2O3, CAS 115200-30-1
Ici 204879
CAS 115200-30-1C23H29Cl3N2O3
DIPPA hydrochloride chemical structure, C22H24Cl3N3OS, CAS 155512-52-0
DIPPA hydrochloride
CAS 155512-52-0C22H24Cl3N3OS
N-MPPP Hydrochloride chemical structure, C21H27ClN2O, CAS 1186195-61-8
N-MPPP Hydrochloride
CAS 1186195-61-8C21H27ClN2O