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Murcko scaffold

Ring system with 4 rings and 23 atoms

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
7
With full pages
4
Scaffold SMILES

O=C(c1ccccc1)c1ccc2cc(-c3ccncc3)ccn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)c1ccc2cc(-c3ccncc3)ccn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

1,2-Bis(propylsulfonyl)-7-(4-pyridyl)indolizin-3-yl 4-fluorophenyl ketone chemical structure, C26H25FN2O5S2, CAS 311783-33-2
1,2-Bis(propylsulfonyl)-7-(4-pyridyl)indolizin-3-yl 4-fluorophenyl ketone
CAS 311783-33-2C26H25FN2O5S2
[1,2-Bis(propylsulfonyl)-7-pyridin-4-ylindolizin-3-yl]-(4-methylphenyl)methanone chemical structure, C27H28N2O5S2, CAS 313067-11-7
[1,2-Bis(propylsulfonyl)-7-pyridin-4-ylindolizin-3-yl]-(4-methylphenyl)methanone
CAS 313067-11-7C27H28N2O5S2
[1,2-Bis(propylsulfonyl)-7-pyridin-4-ylindolizin-3-yl]-(4-methoxyphenyl)methanone chemical structure, C27H28N2O6S2, CAS 313377-26-3
[1,2-Bis(propylsulfonyl)-7-pyridin-4-ylindolizin-3-yl]-(4-methoxyphenyl)methanone
CAS 313377-26-3C27H28N2O6S2
Diisopropyl 3-benzoyl-7-(4-pyridinyl)-1,2-indolizinedicarboxylate chemical structure, C28H26N2O5, CAS 853334-28-8
Diisopropyl 3-benzoyl-7-(4-pyridinyl)-1,2-indolizinedicarboxylate
CAS 853334-28-8C28H26N2O5
Diethyl 3-(4-bromobenzoyl)-7-(4-pyridinyl)-1,2-indolizinedicarboxylate chemical structure, C26H21BrN2O5, CAS 853319-43-4
Diethyl 3-(4-bromobenzoyl)-7-(4-pyridinyl)-1,2-indolizinedicarboxylate
CAS 853319-43-4C26H21BrN2O5
Diisopropyl 3-(4-chlorobenzoyl)-7-(4-pyridinyl)-1,2-indolizinedicarboxylate chemical structure, C28H25ClN2O5, CAS 853334-29-9
Diisopropyl 3-(4-chlorobenzoyl)-7-(4-pyridinyl)-1,2-indolizinedicarboxylate
CAS 853334-29-9C28H25ClN2O5
Diisopropyl 3-(4-bromobenzoyl)-7-(4-pyridinyl)-1,2-indolizinedicarboxylate chemical structure, C28H25BrN2O5, CAS 853334-30-2
Diisopropyl 3-(4-bromobenzoyl)-7-(4-pyridinyl)-1,2-indolizinedicarboxylate
CAS 853334-30-2C28H25BrN2O5