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Murcko scaffold

Ring system with 4 rings and 23 atoms

38 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
38
With full pages
38
Scaffold SMILES

O=C(c1ccccc1)c1ccc2cc(-c3ccccc3)ncn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)c1ccc2cc(-c3ccccc3)ncn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 38 of 38 chemicals

ET 7-(4-BR-Benzoyl)3-(3,4-dimethoxyphenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C25H21BrN2O5, CAS 302912-94-3
ET 7-(4-BR-Benzoyl)3-(3,4-dimethoxyphenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-94-3C25H21BrN2O5
Dimethyl 3-(3,4-dimethoxyphenyl)-7-(4-methoxybenzoyl)pyrrolo(1,2-C)pyrimidine-5,6-dicarboxylate chemical structure, C27H24N2O8, CAS 618070-19-2
Dimethyl 3-(3,4-dimethoxyphenyl)-7-(4-methoxybenzoyl)pyrrolo(1,2-C)pyrimidine-5,6-dicarboxylate
CAS 618070-19-2C27H24N2O8
ET 3-(4-Methylphenyl)-7-(4-nitrobenzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C24H19N3O5, CAS 302913-69-5
ET 3-(4-Methylphenyl)-7-(4-nitrobenzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302913-69-5C24H19N3O5
Ethyl 7-benzoyl-3-(4-methylphenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C24H20N2O3, CAS 302912-96-5
Ethyl 7-benzoyl-3-(4-methylphenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-96-5C24H20N2O3
ET 3-(4-Fluorophenyl)-7-(4-nitrobenzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C23H16FN3O5, CAS 302912-58-9
ET 3-(4-Fluorophenyl)-7-(4-nitrobenzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-58-9C23H16FN3O5
Ethyl 7-(4-bromobenzoyl)-3-(4-bromophenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C23H16Br2N2O3, CAS 302912-78-3
Ethyl 7-(4-bromobenzoyl)-3-(4-bromophenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-78-3C23H16Br2N2O3
ET 7-(4-Fluorobenzoyl)-3-(4-methoxyphenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C24H19FN2O4, CAS 302912-86-3
ET 7-(4-Fluorobenzoyl)-3-(4-methoxyphenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-86-3C24H19FN2O4
ET 7-(4-Bromobenzoyl)-3-(2-chlorophenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C23H16BrClN2O3, CAS 302912-60-3
ET 7-(4-Bromobenzoyl)-3-(2-chlorophenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-60-3C23H16BrClN2O3
ET 7-(4-Chlorobenzoyl)-3-(4-fluorophenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C23H16ClFN2O3, CAS 302912-55-6
ET 7-(4-Chlorobenzoyl)-3-(4-fluorophenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-55-6C23H16ClFN2O3
ET 7-(4-Chlorobenzoyl)-3-(4-chlorophenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C23H16Cl2N2O3, CAS 302912-66-9
ET 7-(4-Chlorobenzoyl)-3-(4-chlorophenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-66-9C23H16Cl2N2O3
ET 3-(3,4-Dimethoxyphenyl)-7-(4-F-benzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C25H21FN2O5, CAS 302912-92-1
ET 3-(3,4-Dimethoxyphenyl)-7-(4-F-benzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-92-1C25H21FN2O5
Dimethyl 3-(2-CL-PH)-7-(4-F-benzoyl)pyrrolo(1,2-C)pyrimidine-5,6-dicarboxylate chemical structure, C24H16ClFN2O5, CAS 302912-99-8
Dimethyl 3-(2-CL-PH)-7-(4-F-benzoyl)pyrrolo(1,2-C)pyrimidine-5,6-dicarboxylate
CAS 302912-99-8C24H16ClFN2O5
ET 7-(4-CL-Benzoyl)3-(2,4-dimethoxyphenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C25H21ClN2O5, CAS 302912-90-9
ET 7-(4-CL-Benzoyl)3-(2,4-dimethoxyphenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-90-9C25H21ClN2O5
ET 3-(4-Bromophenyl)-7-(4-chlorobenzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C23H16BrClN2O3, CAS 302912-76-1
ET 3-(4-Bromophenyl)-7-(4-chlorobenzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-76-1C23H16BrClN2O3
ET 7-(4-Bromobenzoyl)-3-(3-methoxyphenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C24H19BrN2O4, CAS 302912-84-1
ET 7-(4-Bromobenzoyl)-3-(3-methoxyphenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-84-1C24H19BrN2O4
ET 3-(4-Chlorophenyl)-7-(4-methylbenzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C24H19ClN2O3, CAS 302913-70-8
ET 3-(4-Chlorophenyl)-7-(4-methylbenzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302913-70-8C24H19ClN2O3
Ethyl 7-(4-bromobenzoyl)-3-(3-bromophenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C23H16Br2N2O3, CAS 302912-70-5
Ethyl 7-(4-bromobenzoyl)-3-(3-bromophenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-70-5C23H16Br2N2O3
Diethyl 7-(4-CL-benzoyl)-3-(4-ME-PH)pyrrolo(1,2-C)pyrimidine-5,6-dicarboxylate chemical structure, C27H23ClN2O5, CAS 618070-15-8
Diethyl 7-(4-CL-benzoyl)-3-(4-ME-PH)pyrrolo(1,2-C)pyrimidine-5,6-dicarboxylate
CAS 618070-15-8C27H23ClN2O5
ET 3-(4-Methylphenyl)-7-(3-nitrobenzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C24H19N3O5, CAS 302913-68-4
ET 3-(4-Methylphenyl)-7-(3-nitrobenzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302913-68-4C24H19N3O5
ET 3-(4-Chlorophenyl)-7-(4-fluorobenzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C23H16ClFN2O3, CAS 302912-65-8
ET 3-(4-Chlorophenyl)-7-(4-fluorobenzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-65-8C23H16ClFN2O3
ET 7-(4-Bromobenzoyl)-3-(4-fluorophenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C23H16BrFN2O3, CAS 302912-56-7
ET 7-(4-Bromobenzoyl)-3-(4-fluorophenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-56-7C23H16BrFN2O3
ET 7-(4-Bromobenzoyl)-3-(4-methoxyphenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C24H19BrN2O4, CAS 302912-89-6
ET 7-(4-Bromobenzoyl)-3-(4-methoxyphenyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-89-6C24H19BrN2O4
ET 3-(3-Bromophenyl)-7-(4-chlorobenzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate chemical structure, C23H16BrClN2O3, CAS 302912-69-2
ET 3-(3-Bromophenyl)-7-(4-chlorobenzoyl)pyrrolo(1,2-C)pyrimidine-5-carboxylate
CAS 302912-69-2C23H16BrClN2O3
Dimethyl 3-(4-ME-PH)7-(3-nitrobenzoyl)pyrrolo(1,2-C)pyrimidine-5,6-dicarboxylate chemical structure, C25H19N3O7, CAS 618070-17-0
Dimethyl 3-(4-ME-PH)7-(3-nitrobenzoyl)pyrrolo(1,2-C)pyrimidine-5,6-dicarboxylate
CAS 618070-17-0C25H19N3O7