Murcko scaffold
Cyclopropyl phenyl sulfide scaffold
72 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 72
- With full pages
- 14
Scaffold SMILES
c1ccc(SC2CC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 72 chemicals
2-(Diethylamino)ethyl 1-(phenylsulfanyl)cyclopropane-1-carboxylate--hydrogen chloride (1/1)
CAS 84245-04-5C16H24ClNO2S
Cyclopropyl phenyl sulfide
CAS 14633-54-6C9H10S
1-(Trimethylsilyl)cyclopropyl phenyl sulfide
CAS 74379-74-1C12H18SSi
Benzene, ((2,2-dibromocyclopropyl)thio)-
CAS 54061-23-3C9H8Br2S
2,2-Dichlorocyclopropyl phenyl sulfide
CAS 63289-85-0C9H8Cl2S
(1-Iodocyclopropyl)(phenyl)sulfane
CAS 123724-40-3C9H9IS
![[(1-Chlorocyclopropyl)thio]benzene chemical structure, C9H9ClS, CAS 64416-57-5](/s/DSEAFJGJJYHERW-UHFFFAOYSA-N.svg)
[(1-Chlorocyclopropyl)thio]benzene
CAS 64416-57-5C9H9ClS
![[(1-Chloro-2,3-dimethylcyclopropyl)thio]benzene chemical structure, C11H13ClS, CAS 64474-33-5](/s/GJNDPBXIKNJNPJ-UHFFFAOYSA-N.svg)
[(1-Chloro-2,3-dimethylcyclopropyl)thio]benzene
CAS 64474-33-5C11H13ClS
![[(1-Chloro-2,2-dimethylcyclopropyl)thio]benzene chemical structure, C11H13ClS, CAS 5533-19-7](/s/PVMKGOPHSALJRI-UHFFFAOYSA-N.svg)
[(1-Chloro-2,2-dimethylcyclopropyl)thio]benzene
CAS 5533-19-7C11H13ClS
1-(Phenylsulfanyl)cyclopropane-1-carboxylic acid
CAS 36638-57-0C10H10O2S
![[(1-Methoxycyclopropyl)sulfanyl]benzene chemical structure, C10H12OS, CAS 75697-56-2](/s/BWZXHIVCSLMGNR-UHFFFAOYSA-N.svg)
[(1-Methoxycyclopropyl)sulfanyl]benzene
CAS 75697-56-2C10H12OS
1-(Phenylsulfanyl)cyclopropane-1-carbaldehyde
CAS 62240-36-2C10H10OS
1-Chloro-4-(cyclopropylsulfanyl)benzene
CAS 84547-23-9C9H9ClS
![2-[1-(Phenylthio)cyclopropyl]propan-2-ol chemical structure, C12H16OS, CAS 63048-67-9](/s/XAAGUOLFZBAFJY-UHFFFAOYSA-N.svg)
2-[1-(Phenylthio)cyclopropyl]propan-2-ol
CAS 63048-67-9C12H16OS
![2-[1-(Phenylsulfanyl)cyclopropyl]ethan-1-ol chemical structure, C11H14OS, CAS 83022-85-9](/s/MYGZPKIWQJZTPH-UHFFFAOYSA-N.svg)
2-[1-(Phenylsulfanyl)cyclopropyl]ethan-1-ol
CAS 83022-85-9C11H14OS
![Benzene, [(2,2,3,3-tetramethylcyclopropyl)thio]- chemical structure, C13H18S, CAS 100045-89-4](/s/IHOCMMHWEWKLHX-UHFFFAOYSA-N.svg)
Benzene, [(2,2,3,3-tetramethylcyclopropyl)thio]-
CAS 100045-89-4C13H18S
1-((4-Fluorophenyl)thio)cyclopropane-1-carbonitrile
CAS 103574-79-4C10H8FNS
![1-[(2-tert-Butylphenyl)sulfanyl]cyclopropanecarbonitrile chemical structure, C14H17NS, CAS 103575-13-9](/s/FCJKQRKFXWIXHK-UHFFFAOYSA-N.svg)
1-[(2-tert-Butylphenyl)sulfanyl]cyclopropanecarbonitrile
CAS 103575-13-9C14H17NS
trans-Methyl (1S,2R)-2-phenylsulfanylcyclopropane-1-carboxylate
CAS 144407-72-7C11H12O2S
(E)-1-(1-(Phenylthio)cyclopropyl)but-2-EN-1-ol
CAS 63049-00-3C13H16OS
Ethyl (1S,2S)-2-(phenylsulfanyl)cyclopropane-1-carboxylate
CAS 63012-13-5C12H14O2S
4-(Cyclopropylsulfanyl)phenol
CAS 14573-84-3C9H10OS
1-Bromo-4-cyclopropylthiobenzene
CAS 411229-63-5C9H9BrS
(4-(Cyclopropylthio)phenyl)boronic acid
CAS 411229-80-6C9H11BO2S
- 2-(Cyclopropylsulfanyl)aniline1158702-34-1C9H11NS
- 4-(Cyclopropylthio)-2,5-dimethoxyphenethylamine952006-95-0C13H19NO2S
- Ethyl 4-(cyclopropylthio)-alpha-oxobenzeneacetate745052-94-2C13H14O3S
- (1-(Phenylsulfanyl)cyclopropyl)methanamine1311314-26-7C10H13NS
- 3-(Cyclopropylthio)phenylboronic acid2055662-25-2C9H11BO2S
- 1-Bromo-3-cyclopropylthiobenzene1280786-81-3C9H9BrS
- 2-(Cyclopropylsulfanyl)benzonitrile900175-91-9C10H9NS
- 2-Cyclopropylsulfanylbenzaldehyde900175-92-0C10H10OS
- 1-(Cyclopropylsulfanyl)-2-methylbenzene928219-10-7C10H12S
- 1-(4-Cyclopropylsulfanylphenyl)ethanone918967-33-6C11H12OS
- 4-(Cyclopropylsulfanyl)benzoic acid918967-34-7C10H10O2S
- 4-Bromo-2-chloro-1-(cyclopropylsulfanyl)benzene1310947-51-3C9H8BrClS
- 4-Bromo-1-(cyclopropylsulfanyl)-2-methylbenzene1310947-48-8C10H11BrS
- 2-(Cyclopropylthio)-5-nitrobenzaldehyde960234-41-7C10H9NO3S
- Cyclopropyl(4-nitrophenyl)sulfane851008-48-5C9H9NO2S
- Cyclopropyl(4-fluorophenyl)sulfane871657-80-6C9H9FS
- 2-(4-(Cyclopropylsulfanyl)phenyl)acetic acid868614-27-1C11H12O2S
- Ethyl [3-bromo-4-(cyclopropylsulfanyl)phenyl](oxo)acetate1174229-15-2C13H13BrO3S
- 1-Bromo-2-(cyclopropylsulfanyl)benzene1174229-14-1C9H9BrS
- 1-[(4-Bromophenyl)sulfanyl]cyclopropane-1-carboxylic acid1478627-32-5C10H9BrO2S
- [1-(4-Bromophenyl)sulfanylcyclopropyl]methanamine1482192-75-5C10H12BrNS
- (E)-N-(4,4-Diethoxybutyl)-1-[1-(phenylsulfanyl)cyclopropyl]methanimine62240-49-7C18H27NO2S
- (E)-N-Methyl-1-[1-(phenylsulfanyl)cyclopropyl]methanimine62240-46-4C11H13NS
- [(1-Chloro-2,2-diethoxycyclopropyl)sulfanyl]benzene5533-23-3C13H17ClO2S
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(CC2CC2)cc1130 chemicals
c1ccc(OC2CC2)cc157 chemicals
O=C(c1ccccc1)C1CC128 chemicals
c1ccc(NC2CC2)cc120 chemicals
c1ccc(CC2CO2)cc114 chemicals
C1COCC(CC2CO2)C111 chemicals
O=S(=O)(c1ccccc1)C1CC110 chemicals
c1ccc(NC2CC2)nc110 chemicals
C1CCN(CC2CC2)CC19 chemicals
O=C(C1CC1)N1CCNCC17 chemicals
c1cncc(OC2CC2)c17 chemicals
C1CC(NC2CC2)CCN17 chemicals