Murcko scaffold
Ring system with 4 rings and 28 atoms
48 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 28
- Chemicals
- 48
- With full pages
- 1
Scaffold SMILES
O=C(NCCCOc1ccccc1)OCC1c2ccccc2-c2ccccc21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 48 chemicals
N-Fmoc-O-phenyl-D-homoserine
CAS 2137065-53-1C25H23NO5
![(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-phenoxybutanoic acid chemical structure, C25H23NO5, CAS 1821774-68-8](/s/DFSBFNQOGULCOD-QHCPKHFHSA-N.svg)
(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-phenoxybutanoic acid
CAS 1821774-68-8C25H23NO5
![3-[3-(9H-Fluoren-9-ylmethoxycarbonylamino)propoxy]benzoic acid chemical structure, C25H23NO5, CAS 2413876-59-0](/s/OKPNLMPLSOGZPD-UHFFFAOYSA-N.svg)
3-[3-(9H-Fluoren-9-ylmethoxycarbonylamino)propoxy]benzoic acid
CAS 2413876-59-0C25H23NO5
(9H-Fluoren-9-yl)methyl 3-(4-nitrophenoxy)propylcarbamate
CAS 2135916-47-9C24H22N2O5
![2-[4-[3-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-hydroxypropoxy]phenyl]acetic acid chemical structure, C26H25NO6, CAS 2470435-68-6](/s/ZNMSOXXVZIUCMA-UHFFFAOYSA-N.svg)
2-[4-[3-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-hydroxypropoxy]phenyl]acetic acid
CAS 2470435-68-6C26H25NO6
![(9H-Fluoren-9-yl)methyl N-[3-(4-amino-2-chlorophenoxy)-2-hydroxypropyl]-N-ethylcarbamate chemical structure, C26H27ClN2O4, CAS 2172087-03-3](/s/ZWNZPGAYJZKQPB-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-[3-(4-amino-2-chlorophenoxy)-2-hydroxypropyl]-N-ethylcarbamate
CAS 2172087-03-3C26H27ClN2O4
![(9H-Fluoren-9-yl)methyl N-[3-(4-amino-2-chlorophenoxy)-2-hydroxypropyl]-N-(propan-2-yl)carbamate chemical structure, C27H29ClN2O4, CAS 2172075-18-0](/s/VNIXOGHYZNGUTE-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-[3-(4-amino-2-chlorophenoxy)-2-hydroxypropyl]-N-(propan-2-yl)carbamate
CAS 2172075-18-0C27H29ClN2O4
![(9H-Fluoren-9-yl)methyl N-[3-(4-amino-2-chlorophenoxy)-2-hydroxypropyl]-N-methylcarbamate chemical structure, C25H25ClN2O4, CAS 2172565-83-0](/s/COAMRDUAHPWXRQ-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-[3-(4-amino-2-chlorophenoxy)-2-hydroxypropyl]-N-methylcarbamate
CAS 2172565-83-0C25H25ClN2O4
![(9H-Fluoren-9-yl)methyl N-[3-(4-acetamidophenoxy)-2-hydroxypropyl]-N-(propan-2-yl)carbamate chemical structure, C29H32N2O5, CAS 2680696-70-0](/s/QHGWOXXXCIZLHZ-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-[3-(4-acetamidophenoxy)-2-hydroxypropyl]-N-(propan-2-yl)carbamate
CAS 2680696-70-0C29H32N2O5
![(9H-Fluoren-9-yl)methyl N-ethyl-N-{2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl}carbamate chemical structure, C29H33NO5, CAS 2764015-18-9](/s/UOIGXVWVZFNDCS-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-ethyl-N-{2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl}carbamate
CAS 2764015-18-9C29H33NO5
![(9H-Fluoren-9-yl)methyl N-{2-hydroxy-3-[4-(trifluoromethyl)phenoxy]propyl}carbamate chemical structure, C25H22F3NO4, CAS 2764004-54-6](/s/OQPQHJDOADIVBM-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-{2-hydroxy-3-[4-(trifluoromethyl)phenoxy]propyl}carbamate
CAS 2764004-54-6C25H22F3NO4
![(9H-Fluoren-9-yl)methyl N-[3-(2-bromophenoxy)-2-hydroxypropyl]carbamate chemical structure, C24H22BrNO4, CAS 2764014-65-3](/s/CMBGLPKCRFWVMM-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-[3-(2-bromophenoxy)-2-hydroxypropyl]carbamate
CAS 2764014-65-3C24H22BrNO4
(9H-Fluoren-9-yl)methyl N-(2-hydroxy-3-phenoxypropyl)carbamate
CAS 1823249-42-8C24H23NO4
![(9H-Fluoren-9-yl)methyl N-[3-(3-fluorophenoxy)-2-hydroxypropyl]carbamate chemical structure, C24H22FNO4, CAS 2763919-06-6](/s/YJZLGHUQYFLXGE-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-[3-(3-fluorophenoxy)-2-hydroxypropyl]carbamate
CAS 2763919-06-6C24H22FNO4
![(9H-Fluoren-9-yl)methyl N-{2-hydroxy-3-[4-(trifluoromethyl)phenoxy]propyl}-N-methylcarbamate chemical structure, C26H24F3NO4, CAS 2764006-18-8](/s/NBKYOAZPAIGNTM-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-{2-hydroxy-3-[4-(trifluoromethyl)phenoxy]propyl}-N-methylcarbamate
CAS 2764006-18-8C26H24F3NO4
![(9H-Fluoren-9-yl)methyl N-{2-hydroxy-3-[2-(trifluoromethyl)phenoxy]propyl}-N-methylcarbamate chemical structure, C26H24F3NO4, CAS 2764004-67-1](/s/HXISZKIQUPSAKW-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-{2-hydroxy-3-[2-(trifluoromethyl)phenoxy]propyl}-N-methylcarbamate
CAS 2764004-67-1C26H24F3NO4
![(9H-Fluoren-9-yl)methyl N-[3-(4-formylphenoxy)-2-hydroxypropyl]-N-(propan-2-yl)carbamate chemical structure, C28H29NO5, CAS 2764005-45-8](/s/ISDUAVUXHVCBFB-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-[3-(4-formylphenoxy)-2-hydroxypropyl]-N-(propan-2-yl)carbamate
CAS 2764005-45-8C28H29NO5
![(9H-Fluoren-9-yl)methyl N-{2-hydroxy-3-[2-(propan-2-yl)phenoxy]propyl}carbamate chemical structure, C27H29NO4, CAS 2763909-33-5](/s/WSBKCEBFDJJRJJ-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-{2-hydroxy-3-[2-(propan-2-yl)phenoxy]propyl}carbamate
CAS 2763909-33-5C27H29NO4
![(9H-Fluoren-9-yl)methyl N-[2-hydroxy-3-(4-iodophenoxy)propyl]carbamate chemical structure, C24H22INO4, CAS 2763920-25-6](/s/XZUDPIVJGKZVCW-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-[2-hydroxy-3-(4-iodophenoxy)propyl]carbamate
CAS 2763920-25-6C24H22INO4
![(9H-Fluoren-9-yl)methyl N-[3-(3,4-difluorophenoxy)-2-hydroxypropyl]carbamate chemical structure, C24H21F2NO4, CAS 2764020-61-1](/s/JNUVHYAZTRRSLI-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-[3-(3,4-difluorophenoxy)-2-hydroxypropyl]carbamate
CAS 2764020-61-1C24H21F2NO4
![(9H-Fluoren-9-yl)methyl N-(butan-2-yl)-N-[3-(3-chlorophenoxy)-2-hydroxypropyl]carbamate chemical structure, C28H30ClNO4, CAS 2763930-44-3](/s/VRKHEDCXUCRZGJ-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-(butan-2-yl)-N-[3-(3-chlorophenoxy)-2-hydroxypropyl]carbamate
CAS 2763930-44-3C28H30ClNO4
(9H-Fluoren-9-yl)methyl N-(2-hydroxy-3-phenoxypropyl)-N-(propan-2-yl)carbamate
CAS 2763993-54-8C27H29NO4
![(9H-Fluoren-9-yl)methyl N-[3-(3,5-dichlorophenoxy)-2-hydroxypropyl]-N-methylcarbamate chemical structure, C25H23Cl2NO4, CAS 2763994-51-8](/s/HTTJRSVKRRAHLI-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-[3-(3,5-dichlorophenoxy)-2-hydroxypropyl]-N-methylcarbamate
CAS 2763994-51-8C25H23Cl2NO4
![(9H-Fluoren-9-yl)methyl N-{2-hydroxy-3-[2-(methylsulfanyl)phenoxy]propyl}-N-(propan-2-yl)carbamate chemical structure, C28H31NO4S, CAS 2763954-62-5](/s/VXPBBFOKBGJPEI-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl N-{2-hydroxy-3-[2-(methylsulfanyl)phenoxy]propyl}-N-(propan-2-yl)carbamate
CAS 2763954-62-5C28H31NO4S
- (9H-Fluoren-9-yl)methyl N-[2-hydroxy-3-(3-methylphenoxy)propyl]-N-(propan-2-yl)carbamate2763912-75-8C28H31NO4
- (9H-Fluoren-9-yl)methyl N-[3-(2-acetyl-4-acetamidophenoxy)-2-hydroxypropyl]-N-(propan-2-yl)carbamate2763965-62-2C31H34N2O6
- Methyl 2-{4-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-hydroxypropoxy]phenyl}acetate2764019-32-9C27H27NO6
- (9H-Fluoren-9-yl)methyl N-[3-(4-ethylphenoxy)-2-hydroxypropyl]-N-methylcarbamate2763925-79-5C27H29NO4
- (9H-Fluoren-9-yl)methyl N-[2-hydroxy-3-(3-methylphenoxy)propyl]carbamate2764020-71-3C25H25NO4
- (9H-Fluoren-9-yl)methyl N-[3-(4-fluorophenoxy)-2-hydroxypropyl]carbamate2764012-51-1C24H22FNO4
- (9H-Fluoren-9-yl)methyl N-[3-(2,6-dimethylphenoxy)-2-hydroxypropyl]carbamate2763925-92-2C26H27NO4
- (9H-Fluoren-9-yl)methyl N-[3-(2,3-dichlorophenoxy)-2-hydroxypropyl]carbamate2764003-77-0C24H21Cl2NO4
- (9H-Fluoren-9-yl)methyl N-[2-hydroxy-3-(4-nitrophenoxy)propyl]carbamate2763910-03-6C24H22N2O6
- (9H-Fluoren-9-yl)methyl N-[2-hydroxy-3-(4-nitrophenoxy)propyl]-N-methylcarbamate2764008-76-4C25H24N2O6
- (9H-Fluoren-9-yl)methyl N-[3-(4-ethylphenoxy)-2-hydroxypropyl]carbamate2763926-32-3C26H27NO4
- (9H-Fluoren-9-yl)methyl N-{2-hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl}carbamate2764014-14-2C27H29NO5
- (9H-Fluoren-9-yl)methyl N-[3-(2-chloro-5-methylphenoxy)-2-hydroxypropyl]-N-(propan-2-yl)carbamate2764015-42-9C28H30ClNO4
- 4-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)propoxy]benzoic acid2870672-97-0C25H23NO5
- (9H-Fluoren-9-yl)methyl N-{2-hydroxy-3-[3-(trifluoromethyl)phenoxy]propyl}carbamate2764016-31-9C25H22F3NO4
- N-Fmoc-O-(4-chlorophenyl)-L-homoserine2349900-91-8C25H22ClNO5
- N-Fmoc-O-(3-fluorophenyl)-L-homoserine2350562-54-6C25H22FNO5
- N-Fmoc-O-(4-chlorophenyl)-D-homoserine2349953-06-4C25H22ClNO5
- N-Fmoc-O-(4-fluorophenyl)-L-homoserine2349970-46-1C25H22FNO5
- N-Fmoc-O-(4-fluorophenyl)-D-homoserine2350005-82-0C25H22FNO5
- N-Fmoc-O-(3-fluorophenyl)-D-homoserine2349607-85-6C25H22FNO5
- N-Fmoc-O-(2-methoxyphenyl)-L-homoserine2350599-19-6C26H25NO6
- N-Fmoc-O-(2-methoxyphenyl)-D-homoserine2350153-01-2C26H25NO6
- N-Fmoc-O-(2-fluorophenyl)-L-homoserine2382396-43-0C25H22FNO5
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(NCCOCc1ccccc1)OCC1c2ccccc2-c2ccccc213 chemicals
O=C(CNC(=O)OCC1c2ccccc2-c2ccccc21)OCc1ccccc11 chemical![Scaffold O=C(NCC[Se]Cc1ccccc1)OCC1c2ccccc2-c2ccccc21](/scaffold/LDIGTBTXTBHQAP-UHFFFAOYSA-N/structure.svg)
O=C(NCC[Se]Cc1ccccc1)OCC1c2ccccc2-c2ccccc211 chemical
O=C(NCCC=Cc1ccccc1)OCC1c2ccccc2-c2ccccc211 chemical
O=C(CCn1c2c(c3ccccc31)CCCC2)NN=CC=Cc1ccccc11 chemical
O=C(NCCSSc1ccccc1)OCC1c2ccccc2-c2ccccc211 chemical