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Murcko scaffold

Ring system with 4 rings and 28 atoms

276 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
276
With full pages
3
Scaffold SMILES

O=C(NCCOCc1ccccc1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCOCc1ccccc1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 276 chemicals

Fmoc-DL-Ser(Bzl)-OH chemical structure, C25H23NO5, CAS 318996-98-4
Fmoc-DL-Ser(Bzl)-OH
CAS 318996-98-4C25H23NO5
Fmoc-O-benzyl-L-serine chemical structure, C25H23NO5, CAS 83792-48-7
Fmoc-O-benzyl-L-serine
CAS 83792-48-7C25H23NO5
(2R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenylmethoxypropanoic acid chemical structure, C25H23NO5, CAS 122889-11-6
(2R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenylmethoxypropanoic acid
CAS 122889-11-6C25H23NO5
Fmoc-O-benzyl-L-seryl chloride chemical structure, C25H22ClNO4, CAS 157506-72-4
Fmoc-O-benzyl-L-seryl chloride
CAS 157506-72-4C25H22ClNO4
N-Fmoc DMNB-L-serine chemical structure, C27H26N2O9, CAS 628280-43-3
N-Fmoc DMNB-L-serine
CAS 628280-43-3C27H26N2O9
Fmoc-N-Me-Thr(Bzl)-OH chemical structure, C27H27NO5, CAS 198561-81-8
Fmoc-N-Me-Thr(Bzl)-OH
CAS 198561-81-8C27H27NO5
N-Fmoc-N-methyl-O-benzyl-D-serine chemical structure, C26H25NO5, CAS 84000-15-7
N-Fmoc-N-methyl-O-benzyl-D-serine
CAS 84000-15-7C26H25NO5
(2S,3R)-3-(Benzyloxy)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)butanoic acid chemical structure, C26H25NO5, CAS 117872-75-0
(2S,3R)-3-(Benzyloxy)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)butanoic acid
CAS 117872-75-0C26H25NO5
(9H-Fluoren-9-yl)methyl N-[(2R)-1-(benzyloxy)-3-hydroxypropan-2-yl]carbamate chemical structure, C25H25NO4, CAS 611209-95-1
(9H-Fluoren-9-yl)methyl N-[(2R)-1-(benzyloxy)-3-hydroxypropan-2-yl]carbamate
CAS 611209-95-1C25H25NO4
Fmoc-MeSer(Bzl)-OH chemical structure, C26H25NO5, CAS 84000-14-6
Fmoc-MeSer(Bzl)-OH
CAS 84000-14-6C26H25NO5
(2R,3S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(benzyloxy)butanoic acid chemical structure, C26H25NO5, CAS 131545-63-6
(2R,3S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(benzyloxy)butanoic acid
CAS 131545-63-6C26H25NO5
(3R)-4-(Benzyloxy)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid chemical structure, C26H25NO5, CAS 1233495-08-3
(3R)-4-(Benzyloxy)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
CAS 1233495-08-3C26H25NO5
N-Fmoc-3-amino-4-(benzyloxy)butanoic acid chemical structure, C26H25NO5, CAS 1822814-12-9
N-Fmoc-3-amino-4-(benzyloxy)butanoic acid
CAS 1822814-12-9C26H25NO5
(9H-Fluoren-9-yl)methyl N-[(2S)-1-(benzyloxy)-3-hydroxypropan-2-yl]carbamate chemical structure, C25H25NO4, CAS 1189357-54-7
(9H-Fluoren-9-yl)methyl N-[(2S)-1-(benzyloxy)-3-hydroxypropan-2-yl]carbamate
CAS 1189357-54-7C25H25NO4
Fmoc-thr(bzl)-cl chemical structure, C26H24ClNO4, CAS 1423018-08-9
Fmoc-thr(bzl)-cl
CAS 1423018-08-9C26H24ClNO4
N-Fmoc-N-methyl-O-benzyl-D-allothreonine chemical structure, C27H27NO5, CAS 2381364-20-9
N-Fmoc-N-methyl-O-benzyl-D-allothreonine
CAS 2381364-20-9C27H27NO5
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(benzyloxy)butanoic acid chemical structure, C26H25NO5, CAS 1313054-84-0
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(benzyloxy)butanoic acid
CAS 1313054-84-0C26H25NO5
3-[3-(Benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-4-methylpentanoic acid chemical structure, C32H36N2O6, CAS 2171789-01-6
3-[3-(Benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-4-methylpentanoic acid
CAS 2171789-01-6C32H36N2O6
2-[3-(Benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3-methoxy-2-methylpropanoic acid chemical structure, C31H34N2O7, CAS 2171623-16-6
2-[3-(Benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3-methoxy-2-methylpropanoic acid
CAS 2171623-16-6C31H34N2O7
3-[(2R,3S)-3-(Benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-4-methylpentanoic acid chemical structure, C32H36N2O6, CAS 2171427-01-1
3-[(2R,3S)-3-(Benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-4-methylpentanoic acid
CAS 2171427-01-1C32H36N2O6
2-[(2R,3S)-3-(Benzyloxy)-N-tert-butyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]acetic acid chemical structure, C32H36N2O6, CAS 2171266-75-2
2-[(2R,3S)-3-(Benzyloxy)-N-tert-butyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]acetic acid
CAS 2171266-75-2C32H36N2O6
3-[(2R,3S)-3-(Benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-4,4-difluorobutanoic acid chemical structure, C30H30F2N2O6, CAS 2171323-47-8
3-[(2R,3S)-3-(Benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-4,4-difluorobutanoic acid
CAS 2171323-47-8C30H30F2N2O6
8-[(2R,3S)-3-(Benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]octanoic acid chemical structure, C34H40N2O6, CAS 2171150-53-9
8-[(2R,3S)-3-(Benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]octanoic acid
CAS 2171150-53-9C34H40N2O6
4-(Benzyloxy)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanoic acid chemical structure, C27H27NO5, CAS 2139215-10-2
4-(Benzyloxy)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanoic acid
CAS 2139215-10-2C27H27NO5