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Murcko scaffold

2-Oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]-N-phenylacetamide scaffold

54 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
29
Chemicals
54
With full pages
10
Scaffold SMILES

O=C(Nc1ccccc1)C(=O)c1cn(CC(=O)N2CCCCC2)c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]-N-phenylacetamide page
Murcko scaffold O=C(Nc1ccccc1)C(=O)c1cn(CC(=O)N2CCCCC2)c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 54 chemicals

N-Methyl-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]-N-phenylacetamide chemical structure, C24H25N3O3, CAS 872861-45-5
N-Methyl-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]-N-phenylacetamide
CAS 872861-45-5C24H25N3O3
N-Ethyl-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]-N-phenylacetamide chemical structure, C25H27N3O3, CAS 872861-46-6
N-Ethyl-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]-N-phenylacetamide
CAS 872861-46-6C25H27N3O3
2-Oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]-N-phenylacetamide chemical structure, C23H23N3O3, CAS 872861-49-9
2-Oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]-N-phenylacetamide
CAS 872861-49-9C23H23N3O3
N-(4-Methoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C24H25N3O4, CAS 872862-00-5
N-(4-Methoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872862-00-5C24H25N3O4
N-(2-Ethoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C25H27N3O4, CAS 872862-01-6
N-(2-Ethoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872862-01-6C25H27N3O4
N-(4-Ethoxyphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C25H27N3O4, CAS 872862-02-7
N-(4-Ethoxyphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide
CAS 872862-02-7C25H27N3O4
N-(2-Methylsulfanylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C24H25N3O3S, CAS 872862-04-9
N-(2-Methylsulfanylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide
CAS 872862-04-9C24H25N3O3S
N-(4-Acetylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C25H25N3O4, CAS 872862-05-0
N-(4-Acetylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide
CAS 872862-05-0C25H25N3O4
N-(3-Acetylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C25H25N3O4, CAS 872862-06-1
N-(3-Acetylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide
CAS 872862-06-1C25H25N3O4
Ethyl 4-[[2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetyl]amino]benzoate chemical structure, C26H27N3O5, CAS 872862-07-2
Ethyl 4-[[2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetyl]amino]benzoate
CAS 872862-07-2C26H27N3O5
Methyl 4-[[2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetyl]amino]benzoate chemical structure, C25H25N3O5, CAS 872862-08-3
Methyl 4-[[2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetyl]amino]benzoate
CAS 872862-08-3C25H25N3O5
N-(2,3-Dimethylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C25H27N3O3, CAS 872862-12-9
N-(2,3-Dimethylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide
CAS 872862-12-9C25H27N3O3
N-(2,4-Dimethylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C25H27N3O3, CAS 872862-13-0
N-(2,4-Dimethylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide
CAS 872862-13-0C25H27N3O3
N-(2,5-Dimethylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C25H27N3O3, CAS 872862-14-1
N-(2,5-Dimethylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide
CAS 872862-14-1C25H27N3O3
N-(3,4-Dimethylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C25H27N3O3, CAS 872862-15-2
N-(3,4-Dimethylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide
CAS 872862-15-2C25H27N3O3
N-(2,6-Dimethylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C25H27N3O3, CAS 872862-16-3
N-(2,6-Dimethylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide
CAS 872862-16-3C25H27N3O3
N-(3,5-Dimethylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C25H27N3O3, CAS 872862-17-4
N-(3,5-Dimethylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide
CAS 872862-17-4C25H27N3O3
N-(3,4-Dimethoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C25H27N3O5, CAS 872862-18-5
N-(3,4-Dimethoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872862-18-5C25H27N3O5
N-(4-Ethoxyphenyl)-N-ethyl-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C27H31N3O4, CAS 872862-44-7
N-(4-Ethoxyphenyl)-N-ethyl-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide
CAS 872862-44-7C27H31N3O4
N-(3,4-Dimethylphenyl)-N-ethyl-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C27H31N3O3, CAS 872862-45-8
N-(3,4-Dimethylphenyl)-N-ethyl-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide
CAS 872862-45-8C27H31N3O3
N-Ethyl-N-(4-ethylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C27H31N3O3, CAS 872862-46-9
N-Ethyl-N-(4-ethylphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide
CAS 872862-46-9C27H31N3O3
N-Ethyl-N-(4-methoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C26H29N3O4, CAS 872862-47-0
N-Ethyl-N-(4-methoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872862-47-0C26H29N3O4
N-(2,4-Dimethoxyphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide chemical structure, C25H27N3O5, CAS 872862-19-6
N-(2,4-Dimethoxyphenyl)-2-oxo-2-[1-(2-oxo-2-piperidin-1-ylethyl)indol-3-yl]acetamide
CAS 872862-19-6C25H27N3O5
N-(2,5-Dimethoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H-indol-3-yl}acetamide chemical structure, C25H27N3O5, CAS 872862-20-9
N-(2,5-Dimethoxyphenyl)-2-oxo-2-{1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H-indol-3-yl}acetamide
CAS 872862-20-9C25H27N3O5