CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 21 atoms

31 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
31
With full pages
4
Scaffold SMILES

O=C(COc1ccccc1)NCc1ccc2c(c1)OCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)NCc1ccc2c(c1)OCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-ethylphenoxy)acetamide chemical structure, C18H19NO4, CAS 329919-96-2
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-ethylphenoxy)acetamide
CAS 329919-96-2C18H19NO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-chloro-3,5-dimethylphenoxy)acetamide chemical structure, C18H18ClNO4, CAS 403714-27-2
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-chloro-3,5-dimethylphenoxy)acetamide
CAS 403714-27-2C18H18ClNO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-chloro-2-methylphenoxy)acetamide chemical structure, C17H16ClNO4, CAS 355831-38-8
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-chloro-2-methylphenoxy)acetamide
CAS 355831-38-8C17H16ClNO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-methoxyphenoxy)acetamide chemical structure, C17H17NO5, CAS 333432-96-5
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-methoxyphenoxy)acetamide
CAS 333432-96-5C17H17NO5
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2,4-dimethylphenoxy)acetamide chemical structure, C18H19NO4, CAS 423151-89-7
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2,4-dimethylphenoxy)acetamide
CAS 423151-89-7C18H19NO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-chloro-3-methylphenoxy)acetamide chemical structure, C17H16ClNO4, CAS 429626-64-2
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-chloro-3-methylphenoxy)acetamide
CAS 429626-64-2C17H16ClNO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2-methoxyphenoxy)acetamide chemical structure, C17H17NO5, CAS 5684-98-0
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2-methoxyphenoxy)acetamide
CAS 5684-98-0C17H17NO5
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-methylphenoxy)acetamide chemical structure, C17H17NO4, CAS 423738-31-2
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-methylphenoxy)acetamide
CAS 423738-31-2C17H17NO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2,6-dimethylphenoxy)acetamide chemical structure, C18H19NO4, CAS 459218-38-3
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2,6-dimethylphenoxy)acetamide
CAS 459218-38-3C18H19NO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-chlorophenoxy)-2-methylpropanamide chemical structure, C18H18ClNO4, CAS 380543-06-6
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-chlorophenoxy)-2-methylpropanamide
CAS 380543-06-6C18H18ClNO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-fluorophenoxy)acetamide chemical structure, C16H14FNO4, CAS 609794-77-6
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-fluorophenoxy)acetamide
CAS 609794-77-6C16H14FNO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2,4-dichlorophenoxy)acetamide chemical structure, C16H13Cl2NO4, CAS 429629-05-0
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2,4-dichlorophenoxy)acetamide
CAS 429629-05-0C16H13Cl2NO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2-bromo-4-propan-2-ylphenoxy)acetamide chemical structure, C19H20BrNO4, CAS 693270-35-8
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2-bromo-4-propan-2-ylphenoxy)acetamide
CAS 693270-35-8C19H20BrNO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-bromo-3,5-dimethylphenoxy)acetamide chemical structure, C18H18BrNO4, CAS 433946-16-8
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-bromo-3,5-dimethylphenoxy)acetamide
CAS 433946-16-8C18H18BrNO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2-bromo-4-methylphenoxy)acetamide chemical structure, C17H16BrNO4, CAS 351423-02-4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2-bromo-4-methylphenoxy)acetamide
CAS 351423-02-4C17H16BrNO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2,4-dichlorophenoxy)propanamide chemical structure, C17H15Cl2NO4, CAS 329694-16-8
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2,4-dichlorophenoxy)propanamide
CAS 329694-16-8C17H15Cl2NO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-phenoxybutanamide chemical structure, C18H19NO4, CAS 313393-14-5
N-(1,3-Benzodioxol-5-ylmethyl)-2-phenoxybutanamide
CAS 313393-14-5C18H19NO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-chloro-2-methylphenoxy)propanamide chemical structure, C18H18ClNO4, CAS 424808-42-4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-chloro-2-methylphenoxy)propanamide
CAS 424808-42-4C18H18ClNO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-phenoxypropanamide chemical structure, C17H17NO4, CAS 349542-23-0
N-(1,3-Benzodioxol-5-ylmethyl)-2-phenoxypropanamide
CAS 349542-23-0C17H17NO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-bromo-2-chlorophenoxy)acetamide chemical structure, C16H13BrClNO4, CAS 430448-13-8
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-bromo-2-chlorophenoxy)acetamide
CAS 430448-13-8C16H13BrClNO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(3-chlorophenoxy)propanamide chemical structure, C17H16ClNO4, CAS 551909-31-0
N-(1,3-Benzodioxol-5-ylmethyl)-2-(3-chlorophenoxy)propanamide
CAS 551909-31-0C17H16ClNO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2-fluorophenoxy)propanamide chemical structure, C17H16FNO4, CAS 608494-00-4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(2-fluorophenoxy)propanamide
CAS 608494-00-4C17H16FNO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(3,5-dimethylphenoxy)propanamide chemical structure, C19H21NO4, CAS 692268-68-1
N-(1,3-Benzodioxol-5-ylmethyl)-2-(3,5-dimethylphenoxy)propanamide
CAS 692268-68-1C19H21NO4
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-chloro-3,5-dimethylphenoxy)propanamide chemical structure, C19H20ClNO4, CAS 692272-43-8
N-(1,3-Benzodioxol-5-ylmethyl)-2-(4-chloro-3,5-dimethylphenoxy)propanamide
CAS 692272-43-8C19H20ClNO4