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Murcko scaffold

Furo(3,4-b)pyridin-5(7H)-one scaffold

25 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
25
With full pages
4
Scaffold SMILES

O=C1OCc2ncccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Furo(3,4-b)pyridin-5(7H)-one page
Murcko scaffold O=C1OCc2ncccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

Furo(3,4-b)pyridin-5(7H)-one chemical structure, C7H5NO2, CAS 5657-51-2
Furo(3,4-b)pyridin-5(7H)-one
CAS 5657-51-2C7H5NO2
7-Methyl-5H,7H-furo(3,4-b)pyridin-5-one chemical structure, C8H7NO2, CAS 26919-04-0
7-Methyl-5H,7H-furo(3,4-b)pyridin-5-one
CAS 26919-04-0C8H7NO2
7,7-Dimethylfuro[3,4-b]pyridin-5(7H)-one chemical structure, C9H9NO2, CAS 111341-58-3
7,7-Dimethylfuro[3,4-b]pyridin-5(7H)-one
CAS 111341-58-3C9H9NO2
7-Methyl-5-oxo-5,7-dihydrofuro[3,4-b]pyridin-7-yl acetate chemical structure, C10H9NO4, CAS 111068-02-1
7-Methyl-5-oxo-5,7-dihydrofuro[3,4-b]pyridin-7-yl acetate
CAS 111068-02-1C10H9NO4
7-Bromo-7-methylfuro[3,4-b]pyridin-5(7H)-one chemical structure, C8H6BrNO2, CAS 111068-04-3
7-Bromo-7-methylfuro[3,4-b]pyridin-5(7H)-one
CAS 111068-04-3C8H6BrNO2
7-Hydroxy-7-methylfuro[3,4-b]pyridin-5(7H)-one chemical structure, C8H7NO3, CAS 117193-96-1
7-Hydroxy-7-methylfuro[3,4-b]pyridin-5(7H)-one
CAS 117193-96-1C8H7NO3
7-Hydroxyfuro[3,4-b]pyridin-5(7H)-one chemical structure, C7H5NO3, CAS 252289-75-1
7-Hydroxyfuro[3,4-b]pyridin-5(7H)-one
CAS 252289-75-1C7H5NO3
3-Chlorofuro[3,4-b]pyridin-5(7H)-one chemical structure, C7H4ClNO2, CAS 868636-46-8
3-Chlorofuro[3,4-b]pyridin-5(7H)-one
CAS 868636-46-8C7H4ClNO2
2-(Hydroxymethyl)-furo[3,4-b]pyridin-5(7H)-one chemical structure, C8H7NO3, CAS 950910-92-6
2-(Hydroxymethyl)-furo[3,4-b]pyridin-5(7H)-one
CAS 950910-92-6C8H7NO3
5-Oxo-5H,7H-furo[3,4-b]pyridine-2-carboxylic acid chemical structure, C8H5NO4, CAS 950910-94-8
5-Oxo-5H,7H-furo[3,4-b]pyridine-2-carboxylic acid
CAS 950910-94-8C8H5NO4
3-Fluorofuro[3,4-b]pyridin-5(7H)-one chemical structure, C7H4FNO2, CAS 868636-59-3
3-Fluorofuro[3,4-b]pyridin-5(7H)-one
CAS 868636-59-3C7H4FNO2
3-Bromo-7H-furo[3,4-b]pyridin-5-one chemical structure, C7H4BrNO2, CAS 1303968-43-5
3-Bromo-7H-furo[3,4-b]pyridin-5-one
CAS 1303968-43-5C7H4BrNO2
2,3-Dichloro-5H,7H-furo[3,4-b]pyridin-5-one chemical structure, C7H3Cl2NO2, CAS 1803589-33-4
2,3-Dichloro-5H,7H-furo[3,4-b]pyridin-5-one
CAS 1803589-33-4C7H3Cl2NO2
3-Nitrofuro[3,4-b]pyridin-5(7H)-one chemical structure, C7H4N2O4, CAS 1823916-79-5
3-Nitrofuro[3,4-b]pyridin-5(7H)-one
CAS 1823916-79-5C7H4N2O4
7-Bromofuro[3,4-b]pyridin-5(7H)-one chemical structure, C7H4BrNO2, CAS 1895913-41-3
7-Bromofuro[3,4-b]pyridin-5(7H)-one
CAS 1895913-41-3C7H4BrNO2
2-Chloro-3,7-dimethylfuro[3,4-b]pyridin-5(7H)-one chemical structure, C9H8ClNO2, CAS 2231075-87-7
2-Chloro-3,7-dimethylfuro[3,4-b]pyridin-5(7H)-one
CAS 2231075-87-7C9H8ClNO2
2-Chloro-3,7,7-trimethyl-furo[3,4-b]pyridin-5-one chemical structure, C10H10ClNO2, CAS 2231075-82-2
2-Chloro-3,7,7-trimethyl-furo[3,4-b]pyridin-5-one
CAS 2231075-82-2C10H10ClNO2
2-Chloro-3-methylfuro[3,4-b]pyridin-5(7H)-one chemical structure, C8H6ClNO2, CAS 2231075-69-5
2-Chloro-3-methylfuro[3,4-b]pyridin-5(7H)-one
CAS 2231075-69-5C8H6ClNO2
2-Amino-7,7-dimethylfuro[3,4-B]pyridin-5(7H)-one chemical structure, C9H10N2O2, CAS 2320463-28-1
2-Amino-7,7-dimethylfuro[3,4-B]pyridin-5(7H)-one
CAS 2320463-28-1C9H10N2O2
2-Methoxy-7,7-dimethyl-furo[3,4-b]pyridin-5-one chemical structure, C10H11NO3, CAS 2673369-25-8
2-Methoxy-7,7-dimethyl-furo[3,4-b]pyridin-5-one
CAS 2673369-25-8C10H11NO3
2-Chloro-7,7-dimethylfuro[3,4-b]pyridin-5(7H)-one chemical structure, C9H8ClNO2, CAS 2673369-26-9
2-Chloro-7,7-dimethylfuro[3,4-b]pyridin-5(7H)-one
CAS 2673369-26-9C9H8ClNO2
2-Chloro-5H,7H-furo[3,4-b]pyridin-5-one chemical structure, C7H4ClNO2, CAS 2763750-05-4
2-Chloro-5H,7H-furo[3,4-b]pyridin-5-one
CAS 2763750-05-4C7H4ClNO2
2-Ethynyl-5H,7H-furo[3,4-b]pyridin-5-one chemical structure, C9H5NO2, CAS 2803847-12-1
2-Ethynyl-5H,7H-furo[3,4-b]pyridin-5-one
CAS 2803847-12-1C9H5NO2
2-Bromo-5H,7H-furo[3,4-b]pyridin-5-one chemical structure, C7H4BrNO2, CAS 2825004-93-9
2-Bromo-5H,7H-furo[3,4-b]pyridin-5-one
CAS 2825004-93-9C7H4BrNO2