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Murcko scaffold

Ring system with 4 rings and 22 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
14
With full pages
3
Scaffold SMILES

c1ccc(Cn2ncc3ccc(-c4ccccc4)nc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cn2ncc3ccc(-c4ccccc4)nc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

1-((4-Chlorophenyl)methyl)-6-phenyl-1H-pyrazolo(3,4-b)pyridine-4-carboxylic acid chemical structure, C20H14ClN3O2, CAS 863669-02-7
1-((4-Chlorophenyl)methyl)-6-phenyl-1H-pyrazolo(3,4-b)pyridine-4-carboxylic acid
CAS 863669-02-7C20H14ClN3O2
1-[(3-Fluorophenyl)methyl]-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C20H14FN3O2, CAS 867329-86-0
1-[(3-Fluorophenyl)methyl]-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 867329-86-0C20H14FN3O2
1-Benzyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C20H15N3O2, CAS 929974-33-4
1-Benzyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 929974-33-4C20H15N3O2
1-((2-Chlorophenyl)methyl)-6-phenyl-1H-pyrazolo(3,4-b)pyridine-4-carboxylic acid chemical structure, C20H14ClN3O2, CAS 929974-35-6
1-((2-Chlorophenyl)methyl)-6-phenyl-1H-pyrazolo(3,4-b)pyridine-4-carboxylic acid
CAS 929974-35-6C20H14ClN3O2
6-(4-Fluorophenyl)-3-methyl-1-(phenylmethyl)-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine chemical structure, C21H15F4N3, CAS 1011396-82-9
6-(4-Fluorophenyl)-3-methyl-1-(phenylmethyl)-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine
CAS 1011396-82-9C21H15F4N3
3-Methyl-1-(4-methylbenzyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C22H19N3O2, CAS 1011397-32-2
3-Methyl-1-(4-methylbenzyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 1011397-32-2C22H19N3O2
1-Benzyl-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C21H17N3O2, CAS 1011398-57-4
1-Benzyl-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 1011398-57-4C21H17N3O2
1-(4-Chlorobenzyl)-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C21H16ClN3O2, CAS 1011400-09-1
1-(4-Chlorobenzyl)-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 1011400-09-1C21H16ClN3O2
1-(2-Chlorobenzyl)-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C21H16ClN3O2, CAS 1011399-97-5
1-(2-Chlorobenzyl)-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 1011399-97-5C21H16ClN3O2
1-(3-Chlorobenzyl)-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C21H16ClN3O2, CAS 1011398-52-9
1-(3-Chlorobenzyl)-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
CAS 1011398-52-9C21H16ClN3O2
Methyl 1-benzyl-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C22H19N3O2, CAS 1011397-77-5
Methyl 1-benzyl-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
CAS 1011397-77-5C22H19N3O2
Methyl 3-methyl-1-(4-methylbenzyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C23H21N3O2, CAS 1011399-01-1
Methyl 3-methyl-1-(4-methylbenzyl)-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
CAS 1011399-01-1C23H21N3O2
Methyl 1-(4-chlorobenzyl)-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C22H18ClN3O2, CAS 1011398-47-2
Methyl 1-(4-chlorobenzyl)-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
CAS 1011398-47-2C22H18ClN3O2
1-(3-Chlorobenzyl)-6-(4-chlorophenyl)-4-(difluoromethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine chemical structure, C21H15Cl2F2N3, CAS 1011397-62-8
1-(3-Chlorobenzyl)-6-(4-chlorophenyl)-4-(difluoromethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine
CAS 1011397-62-8C21H15Cl2F2N3