CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 22 atoms

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
5
With full pages
1
Scaffold SMILES

c1ccc(Cn2cnc3ccc(N4CCOCC4)cc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cn2cnc3ccc(N4CCOCC4)cc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

Gsk-2636771 chemical structure, C22H22F3N3O3, CAS 1372540-25-4
Gsk-2636771
CAS 1372540-25-4C22H22F3N3O3
Methyl 2-methyl-1-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}-6-(4-morpholinyl)-1H-benzimidazole-4-carboxylate chemical structure, C23H24F3N3O3, CAS 1372540-24-3
Methyl 2-methyl-1-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}-6-(4-morpholinyl)-1H-benzimidazole-4-carboxylate
CAS 1372540-24-3C23H24F3N3O3
Methyl 1-[(3-chloro-2-methylphenyl)methyl]-6-(4-morpholinyl)-2-(trifluoromethyl)-1H-benzimidazole-4-carboxylate chemical structure, C22H21ClF3N3O3, CAS 1372540-46-9
Methyl 1-[(3-chloro-2-methylphenyl)methyl]-6-(4-morpholinyl)-2-(trifluoromethyl)-1H-benzimidazole-4-carboxylate
CAS 1372540-46-9C22H21ClF3N3O3
GSK 2636771 dihydrochloride chemical structure, C22H24Cl2F3N3O3, CAS 2108806-07-9
GSK 2636771 dihydrochloride
CAS 2108806-07-9C22H24Cl2F3N3O3
2-Methyl-1-[[3-methyl-4-(trifluoromethyl)phenyl]methyl]-6-morpholin-4-ylbenzimidazole-4-carboxylic acid chemical structure, C22H22F3N3O3, CAS 1421958-41-9
2-Methyl-1-[[3-methyl-4-(trifluoromethyl)phenyl]methyl]-6-morpholin-4-ylbenzimidazole-4-carboxylic acid
CAS 1421958-41-9C22H22F3N3O3