Murcko scaffold
Ring system with 6 rings and 40 atoms
69 chemicals on CompoundList share this ring system.
- Rings
- 6
- Scaffold atoms
- 40
- Chemicals
- 69
- With full pages
- 4
Scaffold SMILES
O=C1C=CC=CCCCCCCCCC=COC2Oc3ccc4cc(c(C=NN5CCNCC5)cc4c3C2=O)N1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 69 of 69 chemicals
25-Deacetyl-23-acetyl Rifampicin (>85%)
C43H58N4O12
Rifampicin N-4'-oxide
C43H58N4O13
![[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21E)-2,15,17,27,29-Pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[(4-methyl-4-oxidopiperazin-4-ium-1-yl)iminomethyl]-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl] acetate chemical structure, C43H58N4O13](/s/HLBLHKPXLRRUNR-CRICWPABSA-N.svg)
[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21E)-2,15,17,27,29-Pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[(4-methyl-4-oxidopiperazin-4-ium-1-yl)iminomethyl]-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl] acetate
C43H58N4O13
Rifampicin-d4
CAS 2747918-60-9C43H58N4O12
Rifampicin impurity 25
C43H58N4O12
25-Deacetyl-21-acetyl rifampicin
C43H58N4O12
Rifampicin-d3
C43H58N4O12
Rifamycin AF/AETP
C44H60N4O12
Rifampicin EP impurity B
C43H58N4O13
Rifampicin impurity 6
C43H58N4O12
Rifampicin impurity 8
C42H56N4O12
25-Deacetyl-21-acetyl rifampicin
C43H58N4O12
25-Deacetyl-23-acetyl Rifampicin (>85%)
C43H58N4O12
Rifampicin N-4 inverted exclamation mark-Oxide
C43H58N4O13
![Rifamycin, 3-[(1-piperazinylimino)methyl]- chemical structure, C42H56N4O12](/s/FKKVFHDDYXJFFL-PZVBQUGYSA-N.svg)
Rifamycin, 3-[(1-piperazinylimino)methyl]-
C42H56N4O12
![[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-Pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[(Z)-(4-methylpiperazin-1-yl)iminomethyl]-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl] acetate, pyrazine-2-carboxamide, pyridine-4-carbohydrazide chemical structure, C54H70N10O14](/s/KVPNBBUKZBDNBJ-VYIRRLAESA-N.svg)
[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-Pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[(Z)-(4-methylpiperazin-1-yl)iminomethyl]-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl] acetate, pyrazine-2-carboxamide, pyridine-4-carbohydrazide
C54H70N10O14
![Rifamycin, 3-[[[4-(4-pyridinylcarbonyl)-1-piperazinyl]imino]methyl]- chemical structure, C43H58N4NaO12+, CAS 105115-07-9](/s/PPGHYTPFGILTSZ-DIVVYZSPSA-N.svg)
Rifamycin, 3-[[[4-(4-pyridinylcarbonyl)-1-piperazinyl]imino]methyl]-
CAS 105115-07-9C43H58N4NaO12+
C97H131N15O36S3
CAS 142987-37-9C97H131N15O36S3
Rifamethoprim
CAS 61498-94-0C57H76N8O15
25-Deacetyl-21-acetyl rifampicin
C43H58N4O12
1,4,8,21,23-Pentaacetyloxy-rifamycin
CAS 1542148-38-8C53H68N4O17
Related scaffolds
Same ring framework with different atoms or bond orders
