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Murcko scaffold

Ring system with 2 rings and 19 atoms

25 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
25
With full pages
11
Scaffold SMILES

O=C(CNS(=O)(=O)c1ccccc1)N1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNS(=O)(=O)c1ccccc1)N1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

N,4-dimethyl-N-[2-(morpholin-4-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C14H20N2O4S, CAS 522662-03-9
N,4-dimethyl-N-[2-(morpholin-4-yl)-2-oxoethyl]benzenesulfonamide
CAS 522662-03-9C14H20N2O4S
N-Ethyl-4-methyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide chemical structure, C15H22N2O4S, CAS 713502-69-3
N-Ethyl-4-methyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide
CAS 713502-69-3C15H22N2O4S
4-Chloro-N-ethyl-N-[2-(morpholin-4-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C14H19ClN2O4S, CAS 717863-66-6
4-Chloro-N-ethyl-N-[2-(morpholin-4-yl)-2-oxoethyl]benzenesulfonamide
CAS 717863-66-6C14H19ClN2O4S
2-Methoxy-N,5-dimethyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide chemical structure, C15H22N2O5S, CAS 710978-43-1
2-Methoxy-N,5-dimethyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide
CAS 710978-43-1C15H22N2O5S
2,5-Dimethoxy-N-methyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide chemical structure, C15H22N2O6S, CAS 712319-63-6
2,5-Dimethoxy-N-methyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide
CAS 712319-63-6C15H22N2O6S
2,5-Dichloro-N-methyl-N-(2-morpholin-4-yl-2-oxo-ethyl)-benzenesulfonamide chemical structure, C13H16Cl2N2O4S, CAS 677012-44-1
2,5-Dichloro-N-methyl-N-(2-morpholin-4-yl-2-oxo-ethyl)-benzenesulfonamide
CAS 677012-44-1C13H16Cl2N2O4S
4-Bromo-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide chemical structure, C12H15BrN2O4S, CAS 639790-04-8
4-Bromo-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide
CAS 639790-04-8C12H15BrN2O4S
4-Methoxy-N,3-dimethyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide chemical structure, C15H22N2O5S, CAS 714203-72-2
4-Methoxy-N,3-dimethyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide
CAS 714203-72-2C15H22N2O5S
3-Chloro-4-methoxy-N-methyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide chemical structure, C14H19ClN2O5S, CAS 712319-81-8
3-Chloro-4-methoxy-N-methyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide
CAS 712319-81-8C14H19ClN2O5S
N,2,4,6-tetramethyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide chemical structure, C16H24N2O4S, CAS 675862-29-0
N,2,4,6-tetramethyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide
CAS 675862-29-0C16H24N2O4S
3-Chloro-N-(1-(2,6-dimethylmorpholino)-1-oxopropan-2-yl)benzenesulfonamide chemical structure, C15H21ClN2O4S, CAS 1008052-12-7
3-Chloro-N-(1-(2,6-dimethylmorpholino)-1-oxopropan-2-yl)benzenesulfonamide
CAS 1008052-12-7C15H21ClN2O4S
4-Bromo-N-ethyl-N-[2-(morpholin-4-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C14H19BrN2O4S, CAS 915912-17-3
4-Bromo-N-ethyl-N-[2-(morpholin-4-yl)-2-oxoethyl]benzenesulfonamide
CAS 915912-17-3C14H19BrN2O4S
2,5-Dichloro-N-ethyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide chemical structure, C14H18Cl2N2O4S, CAS 838887-41-5
2,5-Dichloro-N-ethyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide
CAS 838887-41-5C14H18Cl2N2O4S
4-Ethoxy-N-methyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide chemical structure, C15H22N2O5S, CAS 878423-68-8
4-Ethoxy-N-methyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide
CAS 878423-68-8C15H22N2O5S
N-(2-(2,6-Dimethylmorpholino)-2-oxoethyl)-2,3,5,6-tetramethylbenzenesulfonamide chemical structure, C18H28N2O4S, CAS 690246-13-0
N-(2-(2,6-Dimethylmorpholino)-2-oxoethyl)-2,3,5,6-tetramethylbenzenesulfonamide
CAS 690246-13-0C18H28N2O4S
N-[2-(2,6-Dimethyl-4-morpholinyl)-2-oxoethyl]-3-methoxybenzenesulfonamide chemical structure, C15H22N2O5S, CAS 690246-01-6
N-[2-(2,6-Dimethyl-4-morpholinyl)-2-oxoethyl]-3-methoxybenzenesulfonamide
CAS 690246-01-6C15H22N2O5S
2,4,6-Trimethyl-N-[2-(4-morpholinyl)-2-oxoethyl]benzenesulfonamide chemical structure, C15H22N2O4S, CAS 312917-00-3
2,4,6-Trimethyl-N-[2-(4-morpholinyl)-2-oxoethyl]benzenesulfonamide
CAS 312917-00-3C15H22N2O4S
4-Ethoxy-N-ethyl-3-methyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide chemical structure, C17H26N2O5S, CAS 878425-06-0
4-Ethoxy-N-ethyl-3-methyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide
CAS 878425-06-0C17H26N2O5S
5-Chloro-2-methoxy-N-methyl-N-[2-(morpholin-4-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C14H19ClN2O5S, CAS 878425-18-4
5-Chloro-2-methoxy-N-methyl-N-[2-(morpholin-4-yl)-2-oxoethyl]benzenesulfonamide
CAS 878425-18-4C14H19ClN2O5S
3-Chloro-4-ethoxy-N-ethyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide chemical structure, C16H23ClN2O5S, CAS 915880-13-6
3-Chloro-4-ethoxy-N-ethyl-N-(2-morpholin-4-yl-2-oxoethyl)benzenesulfonamide
CAS 915880-13-6C16H23ClN2O5S
4-Ethoxy-N,3-dimethyl-N-[2-(morpholin-4-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C16H24N2O5S, CAS 947994-56-1
4-Ethoxy-N,3-dimethyl-N-[2-(morpholin-4-yl)-2-oxoethyl]benzenesulfonamide
CAS 947994-56-1C16H24N2O5S
5-Fluoro-2-methoxy-N-methyl-N-[2-(morpholin-4-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C14H19FN2O5S, CAS 931286-22-5
5-Fluoro-2-methoxy-N-methyl-N-[2-(morpholin-4-yl)-2-oxoethyl]benzenesulfonamide
CAS 931286-22-5C14H19FN2O5S
N-Ethyl-5-fluoro-2-methoxy-N-[2-(morpholin-4-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C15H21FN2O5S, CAS 931258-15-0
N-Ethyl-5-fluoro-2-methoxy-N-[2-(morpholin-4-yl)-2-oxoethyl]benzenesulfonamide
CAS 931258-15-0C15H21FN2O5S
4-Methoxy-N-[(1S)-3-methyl-1-(4-morpholinylcarbonyl)butyl]benzenesulfonamide chemical structure, C17H26N2O5S, CAS 1217716-53-4
4-Methoxy-N-[(1S)-3-methyl-1-(4-morpholinylcarbonyl)butyl]benzenesulfonamide
CAS 1217716-53-4C17H26N2O5S