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Murcko scaffold

Ring system with 3 rings and 27 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
17
With full pages
6
Scaffold SMILES

O=C(NCc1ccccc1)C(=Cc1ccccc1)NC(=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1ccccc1)C(=Cc1ccccc1)NC(=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

N-[(E)-3-(Benzylamino)-1-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]benzamide chemical structure, C24H22N2O3, CAS 324071-55-8
N-[(E)-3-(Benzylamino)-1-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]benzamide
CAS 324071-55-8C24H22N2O3
N-(3-(Benzylamino)-1-(4-nitrophenyl)-3-oxoprop-1-en-2-yl)benzamide chemical structure, C23H19N3O4, CAS 300836-00-4
N-(3-(Benzylamino)-1-(4-nitrophenyl)-3-oxoprop-1-en-2-yl)benzamide
CAS 300836-00-4C23H19N3O4
(E)-N-(3-(Benzylamino)-1-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl)-4-nitrobenzamide chemical structure, C24H21N3O5, CAS 302823-32-1
(E)-N-(3-(Benzylamino)-1-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl)-4-nitrobenzamide
CAS 302823-32-1C24H21N3O5
N-[(1Z)-3-(Benzylamino)-3-oxo-1-phenylprop-1-en-2-yl]benzamide chemical structure, C23H20N2O2, CAS 99875-11-3
N-[(1Z)-3-(Benzylamino)-3-oxo-1-phenylprop-1-en-2-yl]benzamide
CAS 99875-11-3C23H20N2O2
N-(1-((Benzylamino)carbonyl)-2-(3-nitrophenyl)vinyl)benzamide chemical structure, C23H19N3O4, CAS 300566-94-3
N-(1-((Benzylamino)carbonyl)-2-(3-nitrophenyl)vinyl)benzamide
CAS 300566-94-3C23H19N3O4
N-[(Z)-1-(4-Chlorophenyl)-3-[(4-methylphenyl)methylamino]-3-oxoprop-1-en-2-yl]-4-methylbenzamide chemical structure, C25H23ClN2O2, CAS 431910-49-5
N-[(Z)-1-(4-Chlorophenyl)-3-[(4-methylphenyl)methylamino]-3-oxoprop-1-en-2-yl]-4-methylbenzamide
CAS 431910-49-5C25H23ClN2O2
N-[(Z)-3-[(4-Methylphenyl)methylamino]-3-oxo-1-(4-propan-2-ylphenyl)prop-1-en-2-yl]benzamide chemical structure, C27H28N2O2, CAS 431925-41-6
N-[(Z)-3-[(4-Methylphenyl)methylamino]-3-oxo-1-(4-propan-2-ylphenyl)prop-1-en-2-yl]benzamide
CAS 431925-41-6C27H28N2O2
4-Methyl-N-[(Z)-3-[(4-methylphenyl)methylamino]-3-oxo-1-phenylprop-1-en-2-yl]benzamide chemical structure, C25H24N2O2, CAS 432001-08-6
4-Methyl-N-[(Z)-3-[(4-methylphenyl)methylamino]-3-oxo-1-phenylprop-1-en-2-yl]benzamide
CAS 432001-08-6C25H24N2O2
N-[3-(Benzylamino)-1-(3-nitrophenyl)-3-oxo-1-propen-2-yl]-4-(tert-butyl)benzamide chemical structure, C27H27N3O4, CAS 431057-40-8
N-[3-(Benzylamino)-1-(3-nitrophenyl)-3-oxo-1-propen-2-yl]-4-(tert-butyl)benzamide
CAS 431057-40-8C27H27N3O4
N-[3-(Benzylamino)-1-(4-methoxyphenyl)-3-oxo-1-propen-2-yl]-4-(tert-butyl)benzamide chemical structure, C28H30N2O3, CAS 433316-64-4
N-[3-(Benzylamino)-1-(4-methoxyphenyl)-3-oxo-1-propen-2-yl]-4-(tert-butyl)benzamide
CAS 433316-64-4C28H30N2O3
N-(1-(Benzylamino)-3-(4-chlorophenyl)-1-oxobut-2-en-2-yl)benzamide chemical structure, C24H21ClN2O2, CAS 445407-43-2
N-(1-(Benzylamino)-3-(4-chlorophenyl)-1-oxobut-2-en-2-yl)benzamide
CAS 445407-43-2C24H21ClN2O2
(2E)-N-Benzyl-2-[(4-nitrophenyl)formamido]-3-phenylprop-2-enamide chemical structure, C23H19N3O4, CAS 302821-81-4
(2E)-N-Benzyl-2-[(4-nitrophenyl)formamido]-3-phenylprop-2-enamide
CAS 302821-81-4C23H19N3O4
N-[(E)-1-(2-Ethoxyphenyl)-3-oxo-3-(1-phenylethylamino)prop-1-en-2-yl]benzamide chemical structure, C26H26N2O3, CAS 1164519-50-9
N-[(E)-1-(2-Ethoxyphenyl)-3-oxo-3-(1-phenylethylamino)prop-1-en-2-yl]benzamide
CAS 1164519-50-9C26H26N2O3
N-[(E)-1-[(Benzylamino)carbonyl]-2-(4-methoxyphenyl)vinyl]-2-chlorobenzamide chemical structure, C24H21ClN2O3, CAS 1321879-48-4
N-[(E)-1-[(Benzylamino)carbonyl]-2-(4-methoxyphenyl)vinyl]-2-chlorobenzamide
CAS 1321879-48-4C24H21ClN2O3
(2E)-N-Benzyl-3-phenyl-2-(phenylformamido)prop-2-enamide chemical structure, C23H20N2O2, CAS 138505-71-2
(2E)-N-Benzyl-3-phenyl-2-(phenylformamido)prop-2-enamide
CAS 138505-71-2C23H20N2O2
N-(1-((Benzylamino)carbonyl)-2-(4-methylphenyl)vinyl)-4-methylbenzamide chemical structure, C25H24N2O2, CAS 307953-51-1
N-(1-((Benzylamino)carbonyl)-2-(4-methylphenyl)vinyl)-4-methylbenzamide
CAS 307953-51-1C25H24N2O2
(2E)-N-Benzyl-3-(2-chlorophenyl)-2-[(4-nitrophenyl)formamido]prop-2-enamide chemical structure, C23H18ClN3O4, CAS 297146-17-9
(2E)-N-Benzyl-3-(2-chlorophenyl)-2-[(4-nitrophenyl)formamido]prop-2-enamide
CAS 297146-17-9C23H18ClN3O4