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Murcko scaffold

3,3-Diphenyl-1-(4-phenylpiperazin-1-yl)propan-1-one scaffold

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
12
With full pages
2
Scaffold SMILES

O=C(CC(c1ccccc1)c1ccccc1)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3,3-Diphenyl-1-(4-phenylpiperazin-1-yl)propan-1-one page
Murcko scaffold O=C(CC(c1ccccc1)c1ccccc1)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

Ketone, beta-(p-chlorophenyl)phenethyl 4-(o-methoxyphenyl)piperazinyl chemical structure, C26H27ClN2O2, CAS 23902-91-2
Ketone, beta-(p-chlorophenyl)phenethyl 4-(o-methoxyphenyl)piperazinyl
CAS 23902-91-2C26H27ClN2O2
Ketone, beta-(p-chlorophenyl)phenethyl 4-(p-tolyl)piperazinyl chemical structure, C26H27ClN2O, CAS 23904-72-5
Ketone, beta-(p-chlorophenyl)phenethyl 4-(p-tolyl)piperazinyl
CAS 23904-72-5C26H27ClN2O
Ketone, beta-(p-chlorophenyl)phenethyl 4-(o-tolyl)piperazinyl chemical structure, C26H27ClN2O, CAS 23904-87-2
Ketone, beta-(p-chlorophenyl)phenethyl 4-(o-tolyl)piperazinyl
CAS 23904-87-2C26H27ClN2O
Ketone, beta-(p-chlorophenyl)phenethyl 4-(m-tolyl)piperazinyl chemical structure, C26H27ClN2O, CAS 23904-88-3
Ketone, beta-(p-chlorophenyl)phenethyl 4-(m-tolyl)piperazinyl
CAS 23904-88-3C26H27ClN2O
Ketone, beta-(p-chlorophenyl)phenethyl 4-(o-chlorophenyl)piperazinyl chemical structure, C25H24Cl2N2O, CAS 25174-66-7
Ketone, beta-(p-chlorophenyl)phenethyl 4-(o-chlorophenyl)piperazinyl
CAS 25174-66-7C25H24Cl2N2O
1-[4-(4-Fluorophenyl)piperazin-1-yl]-3,3-diphenylpropan-1-one chemical structure, C25H25FN2O, CAS 348611-42-7
1-[4-(4-Fluorophenyl)piperazin-1-yl]-3,3-diphenylpropan-1-one
CAS 348611-42-7C25H25FN2O
1-[4-(2,3-Dimethylphenyl)piperazin-1-yl]-3,3-diphenylpropan-1-one chemical structure, C27H30N2O, CAS 349439-56-1
1-[4-(2,3-Dimethylphenyl)piperazin-1-yl]-3,3-diphenylpropan-1-one
CAS 349439-56-1C27H30N2O
1-[4-(3-Chlorophenyl)piperazin-1-yl]-3,3-diphenylpropan-1-one chemical structure, C25H25ClN2O, CAS 348611-43-8
1-[4-(3-Chlorophenyl)piperazin-1-yl]-3,3-diphenylpropan-1-one
CAS 348611-43-8C25H25ClN2O
3,3-Diphenyl-1-(4-phenylpiperazin-1-yl)propan-1-one chemical structure, C25H26N2O, CAS 303132-86-7
3,3-Diphenyl-1-(4-phenylpiperazin-1-yl)propan-1-one
CAS 303132-86-7C25H26N2O
1-[4-(2-Methoxyphenyl)piperazin-1-yl]-3,3-diphenylpropan-1-one chemical structure, C26H28N2O2, CAS 220421-93-2
1-[4-(2-Methoxyphenyl)piperazin-1-yl]-3,3-diphenylpropan-1-one
CAS 220421-93-2C26H28N2O2
1-[4-(2-Fluorophenyl)piperazin-1-yl]-3,3-diphenylpropan-1-one chemical structure, C25H25FN2O, CAS 432532-39-3
1-[4-(2-Fluorophenyl)piperazin-1-yl]-3,3-diphenylpropan-1-one
CAS 432532-39-3C25H25FN2O
1-[4-(4-Methoxyphenyl)piperazin-1-yl]-3,3-diphenylpropan-1-one chemical structure, C26H28N2O2, CAS 693232-40-5
1-[4-(4-Methoxyphenyl)piperazin-1-yl]-3,3-diphenylpropan-1-one
CAS 693232-40-5C26H28N2O2