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Murcko scaffold

Ring system with 4 rings and 27 atoms

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
12
With full pages
2
Scaffold SMILES

c1ccc(C(CCN2CCN(c3ccccc3)CC2)c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C(CCN2CCN(c3ccccc3)CC2)c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

2-Methyl-1,1-diphenyl-3-(4-phenylpiperazin-1-yl)propan-1-ol chemical structure, C26H30N2O, CAS 4082-41-1
2-Methyl-1,1-diphenyl-3-(4-phenylpiperazin-1-yl)propan-1-ol
CAS 4082-41-1C26H30N2O
alpha,alpha-Diphenyl-4-(p-methoxyphenyl)-beta-methyl-1-piperazinepropanol chemical structure, C27H32N2O2, CAS 4082-42-2
alpha,alpha-Diphenyl-4-(p-methoxyphenyl)-beta-methyl-1-piperazinepropanol
CAS 4082-42-2C27H32N2O2
1-Piperazinepropanol, 4-(p-chlorophenyl)-alpha,alpha-diphenyl-beta-methyl- chemical structure, C26H29ClN2O, CAS 4082-43-3
1-Piperazinepropanol, 4-(p-chlorophenyl)-alpha,alpha-diphenyl-beta-methyl-
CAS 4082-43-3C26H29ClN2O
Piperazine, 1-(3,3-diphenylpropyl)-4-phenyl-, dihydrochloride chemical structure, C25H30Cl2N2, CAS 62469-23-2
Piperazine, 1-(3,3-diphenylpropyl)-4-phenyl-, dihydrochloride
CAS 62469-23-2C25H30Cl2N2
3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenyl-2-propanol chemical structure, C25H27ClN2O, CAS 734517-40-9
3-(4-(3-Chlorophenyl)piperazin-1-yl)-1,1-diphenyl-2-propanol
CAS 734517-40-9C25H27ClN2O
Piperazine, 1-(3-(p-chlorophenyl)-3-phenylpropyl)-4-(p-tolyl)-, maleate chemical structure, C30H33ClN2O4, CAS 23904-73-6
Piperazine, 1-(3-(p-chlorophenyl)-3-phenylpropyl)-4-(p-tolyl)-, maleate
CAS 23904-73-6C30H33ClN2O4
Piperazine, 1-(o-chlorophenyl)-4-(3-(p-chlorophenyl)-3-phenylpropyl)-, maleate chemical structure, C29H30Cl2N2O4, CAS 23941-10-8
Piperazine, 1-(o-chlorophenyl)-4-(3-(p-chlorophenyl)-3-phenylpropyl)-, maleate
CAS 23941-10-8C29H30Cl2N2O4
Piperazine, 1-(3-(p-chlorophenyl)-3-phenylpropyl)-4-(o-tolyl)-, maleate chemical structure, C30H33ClN2O4, CAS 23941-11-9
Piperazine, 1-(3-(p-chlorophenyl)-3-phenylpropyl)-4-(o-tolyl)-, maleate
CAS 23941-11-9C30H33ClN2O4
Piperazine, 1-(3-(p-chlorophenyl)-3-phenylpropyl)-4-(m-tolyl)-, maleate chemical structure, C30H33ClN2O4, CAS 23941-12-0
Piperazine, 1-(3-(p-chlorophenyl)-3-phenylpropyl)-4-(m-tolyl)-, maleate
CAS 23941-12-0C30H33ClN2O4
Piperazine, 1-(3-(p-chlorophenyl)-3-phenylpropyl)-4-(o-methoxyphenyl)-, maleate chemical structure, C30H33ClN2O5, CAS 63978-31-4
Piperazine, 1-(3-(p-chlorophenyl)-3-phenylpropyl)-4-(o-methoxyphenyl)-, maleate
CAS 63978-31-4C30H33ClN2O5
1-Piperazineethanol, 4-(3-chlorophenyl)-alpha-(diphenylmethyl)-, hydrochloride (1:2) chemical structure, C25H28Cl2N2O, CAS 193611-72-2
1-Piperazineethanol, 4-(3-chlorophenyl)-alpha-(diphenylmethyl)-, hydrochloride (1:2)
CAS 193611-72-2C25H28Cl2N2O
Ethyl 3-[4-[3,3-bis(4-chlorophenyl)propyl]-1-piperazinyl]benzoate chemical structure, C28H30Cl2N2O2, CAS 301665-78-1
Ethyl 3-[4-[3,3-bis(4-chlorophenyl)propyl]-1-piperazinyl]benzoate
CAS 301665-78-1C28H30Cl2N2O2