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Murcko scaffold

Ring system with 4 rings and 28 atoms

22 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
22
With full pages
5
Scaffold SMILES

O=C(Nc1nnc(-c2ccccc2)o1)c1ccc(S(=O)(=O)N2CCCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nnc(-c2ccccc2)o1)c1ccc(S(=O)(=O)N2CCCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

N-(5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C19H17FN4O4S, CAS 533869-50-0
N-(5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 533869-50-0C19H17FN4O4S
N-[5-(2,4-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]-4-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C21H22N4O6S, CAS 533870-26-7
N-[5-(2,4-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]-4-pyrrolidin-1-ylsulfonylbenzamide
CAS 533870-26-7C21H22N4O6S
N-(5-(3,5-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C21H22N4O6S, CAS 533870-55-2
N-(5-(3,5-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 533870-55-2C21H22N4O6S
N-(5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C19H17ClN4O4S, CAS 501351-78-6
N-(5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 501351-78-6C19H17ClN4O4S
N-(5-(2-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C20H20N4O5S, CAS 501352-03-0
N-(5-(2-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 501352-03-0C20H20N4O5S
N-[5-(3-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]-4-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C20H20N4O5S, CAS 533869-91-9
N-[5-(3-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]-4-pyrrolidin-1-ylsulfonylbenzamide
CAS 533869-91-9C20H20N4O5S
N-(5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C20H20N4O5S, CAS 442881-17-6
N-(5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 442881-17-6C20H20N4O5S
4-(Pyrrolidin-1-ylsulfonyl)-N-(5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazol-2-yl)benzamide chemical structure, C22H24N4O7S, CAS 533871-36-2
4-(Pyrrolidin-1-ylsulfonyl)-N-(5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazol-2-yl)benzamide
CAS 533871-36-2C22H24N4O7S
4-Pyrrolidin-1-ylsulfonyl-N-[5-(3,4,5-triethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamide chemical structure, C25H30N4O7S, CAS 533871-66-8
4-Pyrrolidin-1-ylsulfonyl-N-[5-(3,4,5-triethoxyphenyl)-1,3,4-oxadiazol-2-yl]benzamide
CAS 533871-66-8C25H30N4O7S
N-[5-(3,4-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]-4-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C21H22N4O6S, CAS 921140-31-0
N-[5-(3,4-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]-4-pyrrolidin-1-ylsulfonylbenzamide
CAS 921140-31-0C21H22N4O6S
N-(5-(2,5-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C21H22N4O6S, CAS 920430-06-4
N-(5-(2,5-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 920430-06-4C21H22N4O6S
N-(5-(2,5-Dichlorophenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C19H16Cl2N4O4S, CAS 891133-67-8
N-(5-(2,5-Dichlorophenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 891133-67-8C19H16Cl2N4O4S
N-(5-(4-Bromophenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C19H17BrN4O4S, CAS 891128-94-2
N-(5-(4-Bromophenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 891128-94-2C19H17BrN4O4S
N-(5-(2,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C21H22N4O4S, CAS 891144-75-5
N-(5-(2,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 891144-75-5C21H22N4O4S
N-(5-(2,5-Dimethylphenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C21H22N4O4S, CAS 891118-26-6
N-(5-(2,5-Dimethylphenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 891118-26-6C21H22N4O4S
N-(5-(2-(Methylthio)phenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C20H20N4O4S2, CAS 886908-76-5
N-(5-(2-(Methylthio)phenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 886908-76-5C20H20N4O4S2
N-{5-[3-(Methylsulfanyl)phenyl]-1,3,4-oxadiazol-2-yl}-4-(pyrrolidine-1-sulfonyl)benzamide chemical structure, C20H20N4O4S2, CAS 886912-82-9
N-{5-[3-(Methylsulfanyl)phenyl]-1,3,4-oxadiazol-2-yl}-4-(pyrrolidine-1-sulfonyl)benzamide
CAS 886912-82-9C20H20N4O4S2
N-(5-(4-(Methylthio)phenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C20H20N4O4S2, CAS 886917-10-8
N-(5-(4-(Methylthio)phenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 886917-10-8C20H20N4O4S2
N-(5-(2-(Methylsulfonyl)phenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C20H20N4O6S2, CAS 886921-94-4
N-(5-(2-(Methylsulfonyl)phenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 886921-94-4C20H20N4O6S2
N-(5-(3-(Methylsulfonyl)phenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C20H20N4O6S2, CAS 886928-47-8
N-(5-(3-(Methylsulfonyl)phenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 886928-47-8C20H20N4O6S2
N-(5-(4-(Methylsulfonyl)phenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C20H20N4O6S2, CAS 886910-57-2
N-(5-(4-(Methylsulfonyl)phenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 886910-57-2C20H20N4O6S2
N-(5-(3,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C21H22N4O4S, CAS 941914-74-5
N-(5-(3,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 941914-74-5C21H22N4O4S