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Murcko scaffold

4-(Furan-2-carbonyl)-N-(5-oxo-1-phenylpyrrolidin-3-yl)piperazine-1-carboxamide scaffold

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
10
With full pages
5
Scaffold SMILES

O=C(NC1CC(=O)N(c2ccccc2)C1)N1CCN(C(=O)c2ccco2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Furan-2-carbonyl)-N-(5-oxo-1-phenylpyrrolidin-3-yl)piperazine-1-carboxamide page
Murcko scaffold O=C(NC1CC(=O)N(c2ccccc2)C1)N1CCN(C(=O)c2ccco2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-[1-(4-Ethoxyphenyl)-5-oxopyrrolidin-3-yl]-4-(furan-2-carbonyl)piperazine-1-carboxamide chemical structure, C22H26N4O5, CAS 894010-87-8
N-[1-(4-Ethoxyphenyl)-5-oxopyrrolidin-3-yl]-4-(furan-2-carbonyl)piperazine-1-carboxamide
CAS 894010-87-8C22H26N4O5
4-(Furan-2-carbonyl)-N-[1-(3-methoxyphenyl)-5-oxopyrrolidin-3-yl]piperazine-1-carboxamide chemical structure, C21H24N4O5, CAS 891095-94-6
4-(Furan-2-carbonyl)-N-[1-(3-methoxyphenyl)-5-oxopyrrolidin-3-yl]piperazine-1-carboxamide
CAS 891095-94-6C21H24N4O5
4-(Furan-2-carbonyl)-N-[1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl]piperazine-1-carboxamide chemical structure, C21H24N4O5, CAS 878062-58-9
4-(Furan-2-carbonyl)-N-[1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl]piperazine-1-carboxamide
CAS 878062-58-9C21H24N4O5
N-[1-(3,4-Dimethoxyphenyl)-5-oxopyrrolidin-3-yl]-4-(furan-2-carbonyl)piperazine-1-carboxamide chemical structure, C22H26N4O6, CAS 877641-31-1
N-[1-(3,4-Dimethoxyphenyl)-5-oxopyrrolidin-3-yl]-4-(furan-2-carbonyl)piperazine-1-carboxamide
CAS 877641-31-1C22H26N4O6
N-[1-(4-Chlorophenyl)-5-oxopyrrolidin-3-yl]-4-(furan-2-carbonyl)piperazine-1-carboxamide chemical structure, C20H21ClN4O4, CAS 887466-22-0
N-[1-(4-Chlorophenyl)-5-oxopyrrolidin-3-yl]-4-(furan-2-carbonyl)piperazine-1-carboxamide
CAS 887466-22-0C20H21ClN4O4
4-(Furan-2-carbonyl)-N-(5-oxo-1-phenylpyrrolidin-3-yl)piperazine-1-carboxamide chemical structure, C20H22N4O4, CAS 894003-43-1
4-(Furan-2-carbonyl)-N-(5-oxo-1-phenylpyrrolidin-3-yl)piperazine-1-carboxamide
CAS 894003-43-1C20H22N4O4
4-(Furan-2-carbonyl)-N-(5-oxo-1-(p-tolyl)pyrrolidin-3-yl)piperazine-1-carboxamide chemical structure, C21H24N4O4, CAS 887465-48-7
4-(Furan-2-carbonyl)-N-(5-oxo-1-(p-tolyl)pyrrolidin-3-yl)piperazine-1-carboxamide
CAS 887465-48-7C21H24N4O4
N-[1-(3,4-Dimethylphenyl)-5-oxopyrrolidin-3-yl]-4-(furan-2-carbonyl)piperazine-1-carboxamide chemical structure, C22H26N4O4, CAS 894028-40-1
N-[1-(3,4-Dimethylphenyl)-5-oxopyrrolidin-3-yl]-4-(furan-2-carbonyl)piperazine-1-carboxamide
CAS 894028-40-1C22H26N4O4
N-[1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl]-4-(furan-2-carbonyl)piperazine-1-carboxamide chemical structure, C20H21FN4O4, CAS 887465-91-0
N-[1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl]-4-(furan-2-carbonyl)piperazine-1-carboxamide
CAS 887465-91-0C20H21FN4O4
N-[1-(4-Fluorophenyl)-5-oxopyrrolidin-3-yl]-4-(furan-2-carbonyl)piperazine-1-carboxamide chemical structure, C20H21FN4O4, CAS 894039-23-7
N-[1-(4-Fluorophenyl)-5-oxopyrrolidin-3-yl]-4-(furan-2-carbonyl)piperazine-1-carboxamide
CAS 894039-23-7C20H21FN4O4