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Murcko scaffold

2-(2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl)-6-phenylpyridazin-3(2H)-one scaffold

78 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 28
Chemicals: 78
With full pages: 1

Scaffold SMILES

O=C(Cn1nc(-c2ccccc2)ccc1=O)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-(2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl)-6-phenylpyridazin-3(2H)-one page

Murcko scaffold O=C(Cn1nc(-c2ccccc2)ccc1=O)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 78 chemicals

6-(4-Chlorophenyl)-2-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyridazin-3(2H)-one chemical structure, C22H21ClN4O2, CAS 898201-82-6

6-(4-Chlorophenyl)-2-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyridazin-3(2H)-one

CAS 898201-82-6C₂₂H₂₁ClN₄O₂

6-(4-Methoxyphenyl)-2-{2-[4-(2-methoxyphenyl)piperazino]-2-oxoethyl}-3(2H)-pyridazinone chemical structure, C24H26N4O4, CAS 282089-97-8

6-(4-Methoxyphenyl)-2-{2-[4-(2-methoxyphenyl)piperazino]-2-oxoethyl}-3(2H)-pyridazinone

CAS 282089-97-8C₂₄H₂₆N₄O₄

2-(2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl)-6-phenylpyridazin-3(2H)-one chemical structure, C22H22N4O2, CAS 922901-28-8

2-(2-Oxo-2-(4-phenylpiperazin-1-yl)ethyl)-6-phenylpyridazin-3(2H)-one

CAS 922901-28-8C₂₂H₂₂N₄O₂

6-(4-Methoxyphenyl)-2-[2-oxo-2-(4-phenylpiperazino)ethyl]-3(2H)-pyridazinone chemical structure, C23H24N4O3, CAS 282089-96-7

6-(4-Methoxyphenyl)-2-[2-oxo-2-(4-phenylpiperazino)ethyl]-3(2H)-pyridazinone

CAS 282089-96-7C₂₃H₂₄N₄O₃

6-(4-Ethoxyphenyl)-2-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyridazin-3-one chemical structure, C24H26N4O3, CAS 899990-08-0

6-(4-Ethoxyphenyl)-2-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyridazin-3-one

CAS 899990-08-0C₂₄H₂₆N₄O₃

6-(2-Methoxyphenyl)-2-(2-oxo-2-(4-phenylpiperazin-1-yl)ethyl)pyridazin-3(2H)-one chemical structure, C23H24N4O3, CAS 899946-70-4

6-(2-Methoxyphenyl)-2-(2-oxo-2-(4-phenylpiperazin-1-yl)ethyl)pyridazin-3(2H)-one

CAS 899946-70-4C₂₃H₂₄N₄O₃

6-(4-Ethylphenyl)-2-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyridazin-3-one chemical structure, C24H26N4O2, CAS 899990-24-0

6-(4-Ethylphenyl)-2-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyridazin-3-one

CAS 899990-24-0C₂₄H₂₆N₄O₂

6-(4-Fluorophenyl)-2-(2-oxo-2-(4-phenylpiperazin-1-yl)ethyl)pyridazin-3(2H)-one chemical structure, C22H21FN4O2, CAS 922993-95-1

6-(4-Fluorophenyl)-2-(2-oxo-2-(4-phenylpiperazin-1-yl)ethyl)pyridazin-3(2H)-one

CAS 922993-95-1C₂₂H₂₁FN₄O₂

6-(3-Methoxyphenyl)-2-(2-oxo-2-(4-phenylpiperazin-1-yl)ethyl)pyridazin-3(2H)-one chemical structure, C23H24N4O3, CAS 899753-29-8

6-(3-Methoxyphenyl)-2-(2-oxo-2-(4-phenylpiperazin-1-yl)ethyl)pyridazin-3(2H)-one

CAS 899753-29-8C₂₃H₂₄N₄O₃

2-{2-[4-(4-Fluorophenyl)piperazino]-2-oxoethyl}-6-(4-methoxyphenyl)-3(2H)-pyridazinone chemical structure, C23H23FN4O3, CAS 282089-99-0

2-{2-[4-(4-Fluorophenyl)piperazino]-2-oxoethyl}-6-(4-methoxyphenyl)-3(2H)-pyridazinone

CAS 282089-99-0C₂₃H₂₃FN₄O₃

2-{2-[4-(3-Chlorophenyl)piperazino]-2-oxoethyl}-6-(4-methoxyphenyl)-3(2H)-pyridazinone chemical structure, C23H23ClN4O3, CAS 276680-01-4

2-{2-[4-(3-Chlorophenyl)piperazino]-2-oxoethyl}-6-(4-methoxyphenyl)-3(2H)-pyridazinone

CAS 276680-01-4C₂₃H₂₃ClN₄O₃

2-{2-[4-(4-Chlorophenyl)piperazino]-2-oxoethyl}-6-(4-methoxyphenyl)-3(2H)-pyridazinone chemical structure, C23H23ClN4O3, CAS 282089-98-9

2-{2-[4-(4-Chlorophenyl)piperazino]-2-oxoethyl}-6-(4-methoxyphenyl)-3(2H)-pyridazinone

CAS 282089-98-9C₂₃H₂₃ClN₄O₃

6-(3,4-Dimethoxyphenyl)-2-[2-oxo-2-(4-phenylpiperazino)ethyl]-3(2H)-pyridazinone chemical structure, C24H26N4O4, CAS 922946-93-8

6-(3,4-Dimethoxyphenyl)-2-[2-oxo-2-(4-phenylpiperazino)ethyl]-3(2H)-pyridazinone

CAS 922946-93-8C₂₄H₂₆N₄O₄

6-(2,5-Dimethoxyphenyl)-2-(2-oxo-2-(4-phenylpiperazin-1-yl)ethyl)pyridazin-3(2H)-one chemical structure, C24H26N4O4, CAS 899968-25-3

6-(2,5-Dimethoxyphenyl)-2-(2-oxo-2-(4-phenylpiperazin-1-yl)ethyl)pyridazin-3(2H)-one

CAS 899968-25-3C₂₄H₂₆N₄O₄

6-(4-Bromophenyl)-2-[2-oxo-2-(4-phenylpiperazino)ethyl]-3(2H)-pyridazinone chemical structure, C22H21BrN4O2, CAS 922880-07-7

6-(4-Bromophenyl)-2-[2-oxo-2-(4-phenylpiperazino)ethyl]-3(2H)-pyridazinone

CAS 922880-07-7C₂₂H₂₁BrN₄O₂

2-(2-(4-(4-Chlorophenyl)piperazin-1-yl)-2-oxoethyl)-6-phenylpyridazin-3(2H)-one chemical structure, C22H21ClN4O2, CAS 1211115-90-0

2-(2-(4-(4-Chlorophenyl)piperazin-1-yl)-2-oxoethyl)-6-phenylpyridazin-3(2H)-one

CAS 1211115-90-0C₂₂H₂₁ClN₄O₂

6-(4-Chlorophenyl)-2-{2-[4-(4-chlorophenyl)piperazino]-2-oxoethyl}-3(2H)-pyridazinone chemical structure, C22H20Cl2N4O2, CAS 1211372-05-2

6-(4-Chlorophenyl)-2-{2-[4-(4-chlorophenyl)piperazino]-2-oxoethyl}-3(2H)-pyridazinone

CAS 1211372-05-2C₂₂H₂₀Cl₂N₄O₂

6-(4-Fluorophenyl)-2-{2-[4-(2-methoxyphenyl)piperazino]-2-oxoethyl}-3(2H)-pyridazinone chemical structure, C23H23FN4O3, CAS 1242004-18-7

6-(4-Fluorophenyl)-2-{2-[4-(2-methoxyphenyl)piperazino]-2-oxoethyl}-3(2H)-pyridazinone

CAS 1242004-18-7C₂₃H₂₃FN₄O₃

2-(2-(4-(3-Chlorophenyl)piperazin-1-yl)-2-oxoethyl)-6-phenylpyridazin-3(2H)-one chemical structure, C22H21ClN4O2, CAS 1219553-88-4

2-(2-(4-(3-Chlorophenyl)piperazin-1-yl)-2-oxoethyl)-6-phenylpyridazin-3(2H)-one

CAS 1219553-88-4C₂₂H₂₁ClN₄O₂

2-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)-2-oxoethyl)-6-phenylpyridazin-3(2H)-one chemical structure, C23H24N4O3, CAS 1219555-04-0

2-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)-2-oxoethyl)-6-phenylpyridazin-3(2H)-one

CAS 1219555-04-0C₂₃H₂₄N₄O₃

6-(2-Fluorophenyl)-2-{2-[4-(4-methoxyphenyl)-1-piperazinyl]-2-oxoethyl}-3(2H)-pyridazinone chemical structure, C23H23FN4O3, CAS 1219541-99-7

6-(2-Fluorophenyl)-2-{2-[4-(4-methoxyphenyl)-1-piperazinyl]-2-oxoethyl}-3(2H)-pyridazinone

CAS 1219541-99-7C₂₃H₂₃FN₄O₃

6-(2-Fluorophenyl)-2-{2-[4-(3-methoxyphenyl)-1-piperazinyl]-2-oxoethyl}-3(2H)-pyridazinone chemical structure, C23H23FN4O3, CAS 1219588-79-0

6-(2-Fluorophenyl)-2-{2-[4-(3-methoxyphenyl)-1-piperazinyl]-2-oxoethyl}-3(2H)-pyridazinone

CAS 1219588-79-0C₂₃H₂₃FN₄O₃

2-(2-(4-(4-Fluorophenyl)piperazin-1-yl)-2-oxoethyl)-6-phenylpyridazin-3(2H)-one chemical structure, C22H21FN4O2, CAS 1206152-02-4

2-(2-(4-(4-Fluorophenyl)piperazin-1-yl)-2-oxoethyl)-6-phenylpyridazin-3(2H)-one

CAS 1206152-02-4C₂₂H₂₁FN₄O₂

2-(2-(4-(4-Methoxyphenyl)piperazin-1-yl)-2-oxoethyl)-6-phenylpyridazin-3(2H)-one chemical structure, C23H24N4O3, CAS 1219539-66-8

2-(2-(4-(4-Methoxyphenyl)piperazin-1-yl)-2-oxoethyl)-6-phenylpyridazin-3(2H)-one

CAS 1219539-66-8C₂₃H₂₄N₄O₃