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Carboxylic acids and anhydrides

(±)-2-Hydroxyglutaric acid

Also known as 2-hydroxyglutaric acid, 2-hydroxyglutarate, alpha-hydroxyglutarate

CAS 2889-31-8Formula C5H8O5Molar mass 148.11 g/mol
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(±)-2-Hydroxyglutaric acid chemical structure, C5H8O5, CAS 2889-31-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
2889-31-8
Formula
C5H8O5
Molar mass
148.11 g/mol
HS code
291819
Category
Carboxylic acids and anhydrides

What is (±)-2-Hydroxyglutaric acid?

Plain description, key identifiers and synonyms

2-hydroxyglutaric acid is a 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group. It has a role as a metabolite and a mouse metabolite. It is a dicarboxylic fatty acid and a 2-hydroxydicarboxylic acid. It is functionally related to a glutaric acid. It is a conjugate acid of a 2-hydroxyglutarate and a 2-hydroxyglutarate(1-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-hydroxypentanedioic acid
CAS number
2889-31-8 CAS number cross-checked
Molecular formula
C5H8O5
UNII
RS4M3UYS95
InChIKey
HWXBTNAVRSUOJR-UHFFFAOYSA-N
InChI
InChI=1S/C5H8O5/c6-3(5(9)10)1-2-4(7)8/h3,6H,1-2H2,(H,7,8)(H,9,10)
SMILES (canonical and isomeric)
C(CC(=O)O)C(C(=O)O)O

Synonyms

  • 2-hydroxyglutaric acid
  • 2-hydroxyglutarate
  • alpha-hydroxyglutarate
  • Pentanedioic acid, 2-hydroxy-
  • 2-oxidanylpentanedioic acid
  • 2-Hydroxy-pentanedioic acid
  • (+-)-2-Hydroxyglutaric acid
  • 2-hydroxypentanedioic acid
  • alpha-Hydroxyglutaric acid
  • (+/-)-2-Hydroxyglutaric acid
  • 2,3-Dideoxypentaric acid
  • Glutaric acid, 2-hydroxy-
  • DL-2-Hydroxyglutaric
  • Pentanedioic acid, 2-hydroxy- (9CI)
  • Glutaric acid, 2-hydroxy- (6CI,7CI,8CI)
  • 2-hydroxypentanedioicacid
  • hydroxyglutaric acid
  • ?-Hydroxyglutaric Acid
  • dl-2-Hydroxyglutaric acid
  • 2-Hydroxyglutaric acid, (+/-)-
  • DL-alpha-HYDROXY GLUTARIC ACID, Zn SALT

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
148.11 g/molcalc.
Exact mass
148.0372 Dacalc.
LogP (octanol/water)
-0.7calc.
Topological polar surface area
94.83 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
4calc.
Heavy atoms
10calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.6calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

(±)-2-Hydroxyglutaric acid suppliers

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All 3 suppliers

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Where suppliers are based

3 suppliers in 2 countries

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(±)-2-Hydroxyglutaric acid price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • animal metabolite
  • eukaryotic metabolite
  • mammalian metabolite
  • metabolite
  • mouse metabolite

Pharmacology

Alpha-Hydroxyglutarate is the base form of alpha-hydroxyglutaric acid, which is an intermediate in the synthesis of alpha-ketoglutaric acid. Alpha-hydroxyglutarate accumulates in the blood of patients with 2-hydroxyglutaric aciduria, an organic acid metabolism disorder, which is caused by the genetic mutation of one of the enzymes responsible for the conversion of 2-hydroxyglutaric acid to alpha-ketoglutaric acid.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code (±)-2-Hydroxyglutaric acid is traded under.

HS 2918.19Indicative HS code

Carboxylic acids with alcohol function but without other oxygen function, their…

World exports in 2024
$1.37B
+0.5% vs 2023, imports $1.18B
2019 to 2024
Top exporters
  1. China23.7%
  2. Italy14.7%
  3. India * partner reported12.0%
Top importers
  1. Germany11.7%
  2. South Korea9.8%
  3. Italy9.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for (±)-2-Hydroxyglutaric acid is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about (±)-2-Hydroxyglutaric acid, based on the data on this page

What is (±)-2-Hydroxyglutaric acid?

2-hydroxyglutaric acid is a 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group. It has a role as a metabolite and a mouse metabolite. It is a dicarboxylic fatty acid and a 2-hydroxydicarboxylic acid.

What is the CAS number of (±)-2-Hydroxyglutaric acid?

The CAS registry number of (±)-2-Hydroxyglutaric acid is 2889-31-8.

What is the molecular formula and weight of (±)-2-Hydroxyglutaric acid?

The molecular formula of (±)-2-Hydroxyglutaric acid is C5H8O5 and its molar mass is 148.11 g/mol.

What is (±)-2-Hydroxyglutaric acid used for?

Known uses and roles of (±)-2-Hydroxyglutaric acid include building blocks in research and laboratory, animal metabolite, eukaryotic metabolite, mammalian metabolite, metabolite and 1 more.

Is (±)-2-Hydroxyglutaric acid hazardous?

No GHS hazard classification for (±)-2-Hydroxyglutaric acid is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of (±)-2-Hydroxyglutaric acid?

(±)-2-Hydroxyglutaric acid is usually classified under HS code 291819 (Carboxylic acids with alcohol function but without other oxygen function, their…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy (±)-2-Hydroxyglutaric acid?

CompoundList lists 3 suppliers of (±)-2-Hydroxyglutaric acid in United States and Canada. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of (±)-2-Hydroxyglutaric acid?

Suppliers quote (±)-2-Hydroxyglutaric acid on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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