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Humectants

Ribonolactone

Also known as (3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-one, D-Ribono-gamma-lactone, Ribonic acid, gamma-lactone, D-

CAS 5336-08-3Formula C5H8O5Molar mass 148.11 g/molEC 226-256-5
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Ribonolactone chemical structure, C5H8O5, CAS 5336-08-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
5336-08-3
Formula
C5H8O5
Molar mass
148.11 g/mol
EC number
226-256-5
HS code
293220
Category
Humectants

What is Ribonolactone?

Plain description, key identifiers and synonyms

D-ribono-1,4-lactone is a five-membered form of ribonolactone having D-configuration. It has a role as a metabolite. It is a butan-4-olide and a ribonolactone. It is functionally related to a D-ribonic acid.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-one
CAS number
5336-08-3Other or deprecated CAS: 3327-63-7
EC number
226-256-5
Molecular formula
C5H8O5
UNII
64E63NC231
MDL number
MFCD00063241
INCI name
RIBONOLACTONE
InChIKey
CUOKHACJLGPRHD-BXXZVTAOSA-N
InChI
InChI=1S/C5H8O5/c6-1-2-3(7)4(8)5(9)10-2/h2-4,6-8H,1H2/t2-,3-,4-/m1/s1
Canonical SMILES
O=C1OC(CO)C(O)C1O
Isomeric SMILES
C([C@@H]1[C@H]([C@H](C(=O)O1)O)O)O

Synonyms

  • (3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-one
  • D-Ribono-gamma-lactone
  • Ribonic acid, gamma-lactone, D-
  • D-Ribono-1,4-lactone
  • D-Ribonolactone
  • D(+)-Ribonic acid gamma-lactone
  • Ribono-gamma-lactone
  • D-(+)-Ribono-1,4-lactone
  • D-Ribopentono-1,4-lactone
  • D-(+)-Ribonic acid gamma-lactone
  • (3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one
  • D-Ribonic acid-1,4-Lactone
  • gamma-Lactone of ribonic acid
  • ribono-1,4-lactone
  • (3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-one
  • delta-Ribonolactone
  • gamma-lactone-Ribonate
  • D-Ribonolactone (VAN)
  • D-ribonic acid g-lactone
  • gamma-Lactone of ribonate
  • ribonic acid-gamma-lactone
  • delta-Ribono-gamma-lactone
  • gamma-lactone-Ribonic acid
  • (+)-Ribonolactone
  • delta-Ribono-1,4-lactone
Show all 35 synonyms
  • Ribonic acid-1,4-lactone
  • Ribonic acid, gamma-lactone
  • D-Xylonic acid-1,4-lactone
  • D-(+)-Ribonic-gamma-lactone
  • delta-Ribopentono-1,4-lactone
  • D-(+)-Ribonic acid g-Lactone
  • D-(+)-Ribonone-1.4-lactone
  • Cuokhacjlgprhd-bxxzvtaosa-
  • D-Ribopentono-1,4-lacton
  • delta-(+)-Ribonone-1.4-lactone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
148.11 g/molcalc.
Exact mass
148.0372 Dacalc.
LogP (octanol/water)
-2.37calc.
Topological polar surface area
86.99 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
1calc.
Heavy atoms
10calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.8calc.
Formal charge
0calc.
Stereocentres
3calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCCO1

O=C1CCCO1

1 ring, 6 atoms, the gamma-Butyrolactone ring system.

1,692 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Ribonolactone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 6 suppliers
6 of 6 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

6 suppliers in 3 countries

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Ribonolactone price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Cosmetics.

Cosmetic ingredient, INCI name RIBONOLACTONE(humectant)

Roles

  • metabolite

Cosmetic functions

  • Humectant

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ribonolactone is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ribonolactone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ribonolactone, based on the data on this page

What is Ribonolactone?

D-ribono-1,4-lactone is a five-membered form of ribonolactone having D-configuration. It has a role as a metabolite. It is a butan-4-olide and a ribonolactone. It is functionally related to a D-ribonic acid.

What is the CAS number of Ribonolactone?

The CAS registry number of Ribonolactone is 5336-08-3. Other or deprecated CAS numbers: 3327-63-7.

What is the molecular formula and weight of Ribonolactone?

The molecular formula of Ribonolactone is C5H8O5 and its molar mass is 148.11 g/mol.

What is Ribonolactone used for?

Use classes: Cosmetics.

Is Ribonolactone hazardous?

No GHS hazard classification for Ribonolactone is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Ribonolactone?

Ribonolactone is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ribonolactone?

CompoundList lists 6 suppliers of Ribonolactone in China, United States and Poland. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ribonolactone?

Suppliers quote Ribonolactone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ribonolactone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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