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20beta-Hydroxyprogesterone

Also known as (20R)-20-Hydroxypregn-4-en-3-one, 20-beta-Progerol, Progesterol-20-beta

20beta-Hydroxyprogesterone chemical structure, C21H32O2, CAS 145-15-3
2D chemical structure

Key facts

What buyers check first

CAS number
145-15-3
Formula
C21H32O2
Molar mass
316.49 g/mol
EC number
205-650-0
HS code
291440
Category
Impurities and reference standards

What is 20beta-Hydroxyprogesterone?

Plain description, key identifiers and synonyms

(20R)-20-hydroxypregn-4-en-3-one is a 20-hydroxypregn-4-en-3-one.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(8S,9S,10R,13S,14S,17S)-17-[(1R)-1-hydroxyethyl]-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
CAS number
145-15-3
EC number
205-650-0
Molecular formula
C21H32O2
UNII
67N4JZ6CHL
InChIKey
RWBRUCCWZPSBFC-SJOKZOANSA-N
InChI
InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12-13,16-19,22H,4-11H2,1-3H3/t13-,16+,17-,18+,19+,20+,21-/m1/s1
Canonical SMILES
CC(O)C1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C
Isomeric SMILES
C[C@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O

Synonyms

  • (20R)-20-Hydroxypregn-4-en-3-one
  • 20-beta-Progerol
  • Progesterol-20-beta
  • 20-beta-Dihydroprogesterone
  • 20-beta-Hydroxyprogesterone
  • 20beta-Progerol
  • 4-Pregnen-2-beta-ol-3-one
  • Progesterol-20beta
  • Pregn-4-en-3-one, 20-hydroxy-, (20R)-
  • 20beta-Hydroxypregn-4-en-3-one
  • 20-beta-Hydroxydihydroprogesterone
  • 20-beta-Hydroxypregn-4-en-3-one
  • 20beta-Hydroxy-pregn-4-en-3-one
  • Pregn-4-en-3-one, 20-beta-hydroxy-
  • 20R-hydroxypregn-4-en-3-one
  • 20beta-hydroxy-4-pregnen-3-one
  • Pregn-4-en-3-one, 20-hydroxy-, (20-R)-
  • Progesterone impurity c
  • Progesterone impurity c (ep impurity)
  • Pregn-4-en-3-one, 20-hydroxy-, (20-R)-(9CI)
  • 20b-Dihydroprogesterone
  • Progesterone EP Impurity C
  • 20beta-Dihydroprogesterone
  • (20R)-20-Hydroxypregn-4-en-3-one, Progesterone Imp. C (EP), 20(R)-Hydroxy Progesterone, Progesterone Impurity C
  • (20R)-20-hydroxy-pregn-4-en-3-one
Show all 31 synonyms
  • 20I(2)-Hydroxyprogesterone
  • 4-Pregnen-20?-ol-3-one
  • pregn-4-en-20(r)-ol-3-one
  • 4-Pregnen-20beta-ol-3-one
  • 20beta-Hydroxydihydroprogesterone
  • Pregn-4-en-3-one, 20beta-hydroxy-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
316.49 g/molcalc.
Exact mass
316.2402 Dacalc.
LogP (octanol/water)
4.52calc.
Topological polar surface area
37.3 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
1calc.
Heavy atoms
23calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.86calc.
Formal charge
0calc.
Stereocentres
7calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=C2CCC3C4CCCC4CCC3C2CC1

O=C1C=C2CCC3C4CCCC4CCC3C2CC1

4 rings, 18 atoms.

1,419 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H341Suspected of causing genetic defects.
  • H351Suspected of causing cancer.
  • H360FDMay damage fertility. May damage the unborn child.
Precautionary statements (9)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

20beta-Hydroxyprogesterone suppliers

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Where suppliers are based

1 supplier in 1 country

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20beta-Hydroxyprogesterone price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Applications are not documented for this substance yet. Suppliers often describe uses on their product pages, linked in the suppliers list above.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 20beta-Hydroxyprogesterone is traded under.

HS 2914.40Indicative HS code

Ketone-alcohols and ketone-aldehydes

World exports in 2024
$199M
+2.5% vs 2023, imports $247M
2019 to 2024
Top exporters
  1. China29.5%
  2. Germany14.4%
  3. Netherlands12.7%
Top importers
  1. United States37.2%
  2. Netherlands8.5%
  3. Germany6.4%
Reported customs values in USD, not prices.Full trade data

The HS code shown for 20beta-Hydroxyprogesterone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 20beta-Hydroxyprogesterone, based on the data on this page

What is 20beta-Hydroxyprogesterone?

(20R)-20-hydroxypregn-4-en-3-one is a 20-hydroxypregn-4-en-3-one.

What is the CAS number of 20beta-Hydroxyprogesterone?

The CAS registry number of 20beta-Hydroxyprogesterone is 145-15-3.

What is the molecular formula and weight of 20beta-Hydroxyprogesterone?

The molecular formula of 20beta-Hydroxyprogesterone is C21H32O2 and its molar mass is 316.49 g/mol.

Is 20beta-Hydroxyprogesterone hazardous?

20beta-Hydroxyprogesterone carries the GHS signal word "Danger". Main hazards: harmful if swallowed, suspected of causing genetic defects, suspected of causing cancer. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 20beta-Hydroxyprogesterone?

20beta-Hydroxyprogesterone is usually classified under HS code 291440 (Ketone-alcohols and ketone-aldehydes). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 20beta-Hydroxyprogesterone?

CompoundList lists 1 supplier of 20beta-Hydroxyprogesterone in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of 20beta-Hydroxyprogesterone?

Suppliers quote 20beta-Hydroxyprogesterone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 20beta-Hydroxyprogesterone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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