Key facts
What buyers check first
- Appearance
- White crystals or powder
- Melting point
- 132.7 °C
- Boiling point
- Decomposes
- Density
- G/cm³
- Solubility
- In water, 5.45 × 10⁺⁵ mg/l @ 25 °C
- HS code
- 310210
- Category
- Fertilizers and micronutrients
What is Urea?
Plain description, key identifiers and synonyms
Urea is a carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O). It has a role as a fertilizer, a flour treatment agent, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and a Daphnia magna metabolite. It is a monocarboxylic acid amide and a one-carbon compound. It is functionally related to a carbonic acid. It is a tautomer of a carbamimidic acid.
Urea is the diamide of carbonic acid.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- urea
- CAS number
- 57-13-6 CAS number cross-checkedOther or deprecated CAS: 3138-51-0, 37955-36-5, 4744-36-9
- EC numbers
- 200-315-5, 682-045-1
- Molecular formula
- CH4N2O
- UNII
- 8W8T17847W
- MDL number
- MFCD00008022
- INCI name
- UREA
- InChIKey
- XSQUKJJJFZCRTK-UHFFFAOYSA-N
- InChI
- InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
- SMILES (canonical and isomeric)
- C(=O)(N)N
Synonyms
- carbamide
- Carbonyldiamide
- Ureophil
- Carbonyldiamine
- Ureaphil
- Keratinamin
- Urevert
- Alphadrate
- Aquadrate
- Carbaderm
- Pastaron
- Urepearl
- Carbonyl diamide
- Carbamide resin
- Ultra Mide
- Varioform ii
- Aqua Care
- Harnstoff
- Mocovina
- Nutraplus
- Prespersion, 75 urea
- Supercel 3000
- Aqua Care HP
- Ureacin-10 lotion
- Ureacin-40 Creme
Show all 39 synonymsShow fewer synonyms
- Antisepsis bolus
- Elaqua xx
- Sterile Urea
- Azodicarboxylic acid-diamide
- INS NO.927A
- Lanaphilic
- Flexifoot
- Flexitol
- Protexa
- Vanamide
- UterCleanse
- Xurea
- Balneum plus
- Umecta Mousse
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | White crystals or powderexp.Measured value |
|---|---|
| Odour | MAY GRADUALLY DEVELOP SLIGHT ODOR OF AMMONIA, ESP IN PRESENCE OF MOISTUREexp.Measured value |
| Taste | Cooling, saline tasteexp.Measured value |
| Melting point | 132.7 °Cexp.Measured value |
| Boiling point | Decomposesexp.Measured value |
| Density | G/cm³exp.Measured value |
| Autoignition temperature | Not flammableexp.Measured value |
| Solubility | In water, 5.45 × 10⁺⁵ mg/l @ 25 °Cexp.Measured value |
| Vapour pressure | 1.2 × 10⁻⁵ mm Hg @ 25 °Cexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 60.06 g/molcalc.Computed value |
|---|---|
| Exact mass | 60.0324 Dacalc.Computed value |
| LogP (octanol/water) | -0.98calc.Computed value |
| Topological polar surface area | 69.11 Ųcalc.Computed value |
| Hydrogen bond donors | 2calc.Computed value |
| Hydrogen bond acceptors | 1calc.Computed value |
| Rotatable bonds | 0calc.Computed value |
| Heavy atoms | 4calc.Computed value |
| Rings | 0calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Safety and hazards
GHS classification summary, not a safety data sheet
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidUrea suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- India, Vadodara ManufacturerUnclaimed profileUreaGrade, purity and minimum order on requestPrice on request
- India, Mumbai ManufacturerUnclaimed profileUreaGrade, purity and minimum order on requestPrice on request
- South Korea, Ansan ManufacturerUnclaimed profileUreaGrade, purity and minimum order on requestPrice on request
- South Korea, SeoulUnclaimed profileUreaGrade, purity and minimum order on requestPrice on request
- Price on request
- Switzerland, BinningenUnclaimed profileUreaGrade, purity and minimum order on requestPrice on request
- Price on request
- IrelandUnclaimed profileUreaGrade, purity and minimum order on requestPrice on request
- Thailand, Phra PradaengUnclaimed profileUreaGrade, purity and minimum order on requestPrice on request
- Thailand, SamphanthawongUnclaimed profileUreaGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
338 suppliers in 43 countries
- United States87
- Canada46
- China44
- South Korea41
- India34
- Germany11
- and 37 more countries
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Urea price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
The active ingredient is no longer contained in any registered pesticide products ... "cancelled.".
Condensed with malonic ester to form barbituric acid, cellulose softener.
Liquid & other fertilizer applications, livestock nutrient, monomer for urea-formaldehyde resins, chemical intermediate for melamine.
Industrial uses: Dye, Humectant, Softener and conditioner, Processing aids, specific to petroleum production, Intermediate, Flocculating agent, Solids separation, Adhesion/cohesion promoter.
Consumer uses: Humectant, Intermediate, Anti-scaling agent, Adhesion/cohesion promoter, Soil amendments (fertilizers), Filler, Stabilizing agent.
Use classes: Uncategorized, Safer Chemical Classes, Food additives, Cosmetics.
Industries and functions
Cosmetic ingredient, INCI name UREA(antistatic, buffering, humectant, skin conditioning)
Roles
- Daphnia magna metabolite
- Escherichia coli metabolite
- Saccharomyces cerevisiae metabolite
- additive
- agrochemical
- analgesic
- animal metabolite
- antineoplastic agent
- antipsoriatic
- bacterial metabolite
- dermatologic drug
- eukaryotic metabolite
- fertilizer
- flour treatment agent
- food additive
- food component
- fungal metabolite
- human metabolite
- hypoglycemic agent
- metabolite
- mouse metabolite
- pharmaceutical
- physiological role
- prokaryotic metabolite
Functional uses
- Anti-static agent
- Binder
- Chelating agent
- Dye
- Flame retardant
- Freeze-thaw additive
- Humectant
- Other
- Softener and conditioner
- Soil amendments
- Solubility enhancer
- pH regulating agent
Cosmetic functions
- Antistatic
- Buffering
- Humectant
- Skin conditioning
Pharmacology
Urea is a nitrogenous compound containing a carbonyl group attached to two amine groups with osmotic diuretic activity. In vivo, urea is formed in the liver via the urea cycle from ammonia and is the final end product of protein metabolism. Administration of urea elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain, cerebrospinal fluid and eye, into interstitial fluid and plasma, thereby decreasing pressure in those tissues and increasing urine outflow.
How it is made
From ammonia, carbon monoxide and sulfur in methanol.
Liquid ammonia and liquid carbon dioxide at 1750-3000 psi and 160-200 °C react to form ammonium carbamate, NH4CO2NH2, which decomposes at lower pressure (about 80 psi) to urea and water. Method of purification: crystallization.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- EU cosmetic ingredient inventory
- Active ingredient in FDA approved drug labels
- Food additive
United States
- Safer Choice ingredient list (USA)
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Urea is traded under.
Urea, whether or not in aqueous solution
- Saudi Arabia12.3%
- Oman * partner reported12.0%
- Qatar * partner reported11.0%
- Brazil18.3%
- United States11.6%
- Australia9.0%
* Partner reported figures, a lower bound.
The HS code shown for Urea is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.
Related chemicals
Parent and salt forms, stereoisomers, similar structures and isomers
Salt and hydrate forms
Records that share this compound as their parent
Stereoisomers and isotopic forms
Same connectivity, different stereochemistry or isotopes (same InChIKey skeleton)
Similar structures
Nearest neighbours by Morgan fingerprint Tanimoto similarity
Same formula isomers
Different compounds that share this molecular formula
Frequently asked questions
Quick answers about Urea, based on the data on this page
What is Urea?
What is the CAS number of Urea?
What is the molecular formula and weight of Urea?
What is Urea used for?
Is Urea hazardous?
What is the HS code of Urea?
Where can I buy Urea?
Where can I buy Urea in India?
What is the price of Urea?
Guides for buyers
Practical guides that help when you source, ship or handle Urea
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
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