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Hormones and steroids

Norepinephrine

Also known as L-Noradrenaline, Levarterenol, Arterenol

CAS 51-41-2Formula C8H11NO3Molar mass 169.18 g/molEC 200-096-6
GHS signal word: Danger. Pictograms: Acute toxicity (severe) 64 suppliers listed Drug substance
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Norepinephrine chemical structure, C8H11NO3, CAS 51-41-2
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless microcrystals
Melting point
217 °C
Solubility
Slightly soluble in water, ethanol, diethyl ether, very soluble in alkali, dilute hydroc…
HS code
293790
Category
Hormones and steroids

What is Norepinephrine?

Plain description, key identifiers and synonyms

(R)-noradrenaline is the R-enantiomer of noradrenaline. It has a role as a neurotransmitter, a sympathomimetic agent, an alpha-adrenergic agonist, a vasoconstrictor agent and a mouse metabolite. It is a conjugate base of a (R)-noradrenaline(1+). It is an enantiomer of a (S)-noradrenaline.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol
CAS number
51-41-2 CAS number cross-checkedOther or deprecated CAS: 65277-62-5
EC number
200-096-6
Molecular formula
C8H11NO3
UNII
X4W3ENH1CV
MDL number
MFCD00025592
InChIKey
SFLSHLFXELFNJZ-QMMMGPOBSA-N
InChI
InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1
Canonical SMILES
NCC(O)c1ccc(O)c(O)c1
Isomeric SMILES
C1=CC(=C(C=C1[C@H](CN)O)O)O

Synonyms

  • L-Noradrenaline
  • Levarterenol
  • Arterenol
  • L-Norepinephrine
  • (R)-Noradrenaline
  • (-)-Norepinephrine
  • (-)-Noradrenaline
  • L-arterenol
  • (-)-Arterenol
  • (R)-Norepinephrine
  • 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol
  • Levonoradrenaline
  • Sympathin E
  • Levonorepinephrine
  • (R)-(-)-Norepinephrine
  • Norepirenamine
  • (R)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol
  • Noradrenalin
  • norepinephrinum
  • Noradrenalinum
  • Norartrinal
  • Nor adrenalin
  • Nor-Epirenan
  • norepinefrina
  • Noradrenalina
Show all 38 synonyms
  • L-3,4-dihydroxyphenylethanolamine
  • D-(-)-Noradrenaline
  • l-2-Amino-1-(3,4-dihydroxyphenyl)ethanol
  • (-)-alpha-(Aminomethyl)protocatechuyl alcohol
  • L-alpha-(aminomethyl)-3,4-dihydroxybenzyl alcohol
  • 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol
  • 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (R)-
  • 4-((1R)-2-Amino-1-hydroxyethyl)-1,2-benzenediol
  • 4-((1R)-2-amino-1-hydroxyethyl)benzene-1,2-diol
  • noradranalinum
  • noradrAnaline
  • Norepinephrine 1530
  • (-)-alpha-(Aminomethyl)-3,4-dihydroxybenzyl alcohol

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless microcrystalsexp.
Melting point
217 °Cexp.
Solubility
Slightly soluble in water, ethanol, diethyl ether, very soluble in alkali, dilute hydrochloric acidexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
169.18 g/molcalc.
Exact mass
169.0739 Dacalc.
LogP (octanol/water)
0.09calc.
Topological polar surface area
86.71 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
2calc.
Heavy atoms
12calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.25calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H300Fatal if swallowed.
  • H310Fatal in contact with skin.
  • H330Fatal if inhaled.
Precautionary statements (18)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P316Get emergency medical help immediately.
  • P320Specific treatment is urgent (see supplemental first aid instructions on the label).
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Norepinephrine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 64 suppliers
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Where suppliers are based

64 suppliers in 16 countries

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Norepinephrine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Therapeutic category: Adrenergic (vasopressor), antihypotensive.

Pharmacological actions

  • Adrenergic alpha-Agonists
  • Sympathomimetics
  • Vasoconstrictor Agents

Roles

  • adrenergic agent
  • adrenergic agonist
  • alpha-adrenergic agonist
  • alpha-adrenergic drug
  • animal metabolite
  • anti-inflammatory agent
  • anti-obesity agent
  • antidepressant
  • cardiovascular drug
  • central nervous system drug
  • dermatologic drug
  • eukaryotic metabolite
  • mammalian metabolite
  • metabolite
  • molecular messenger
  • mouse metabolite
  • neuroprotective agent
  • neurotransmitter
  • neurotransmitter agent
  • pharmaceutical
  • protective agent
  • psychotropic drug
  • sympathomimetic agent
  • vasoconstrictor agent

Pharmacology

Norepinephrine is a Catecholamine.

How it is made

Obtained from 4-chloroacetylcatechol which is prepared from catechol by reaction with chloroacetic acid and POCl3.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Noradrenaline and its salts, Ref no: 257, Annex ref: II/257
  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Norepinephrine is traded under.

HS 2937.90Indicative HS code

Derivatives and structural analogues thereof, including chain modified polypeptides, used primarily as…

World exports in 2024
$366M
−8.6% vs 2023, imports $397M
2019 to 2024
Top exporters
  1. France * partner reported31.2%
  2. Ireland21.7%
  3. Germany12.7%
Top importers
  1. United States44.2%
  2. France * partner reported20.3%
  3. China7.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Norepinephrine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Norepinephrine, based on the data on this page

What is Norepinephrine?

(R)-noradrenaline is the R-enantiomer of noradrenaline. It has a role as a neurotransmitter, a sympathomimetic agent, an alpha-adrenergic agonist, a vasoconstrictor agent and a mouse metabolite. It is a conjugate base of a (R)-noradrenaline(1+). It is an enantiomer of a (S)-noradrenaline.

What is the CAS number of Norepinephrine?

The CAS registry number of Norepinephrine is 51-41-2. Other or deprecated CAS numbers: 65277-62-5.

What is the molecular formula and weight of Norepinephrine?

The molecular formula of Norepinephrine is C8H11NO3 and its molar mass is 169.18 g/mol.

What is Norepinephrine used for?

Therapeutic category: Adrenergic (vasopressor), antihypotensive.

Is Norepinephrine hazardous?

Norepinephrine carries the GHS signal word "Danger". Main hazards: fatal if swallowed, fatal in contact with skin, fatal if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Norepinephrine?

Norepinephrine is usually classified under HS code 293790 (Hormones, prostaglandins, thromboxanes and leukotrienes, natural or reproduced by…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Norepinephrine?

CompoundList lists 64 suppliers of Norepinephrine in United States, China, Germany, United Kingdom and 12 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Norepinephrine in India?

1 supplier in India list Norepinephrine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Norepinephrine?

Suppliers quote Norepinephrine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Norepinephrine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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