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Analgesics and anti-inflammatories

3-Methylfentanyl

Also known as Mefentanyl, 3-Methylfentanil, DEA No. 9813

CAS 42045-86-3Formula C23H30N2OMolar mass 350.51 g/mol
Prohibited, not for trade
Why it is not for trade
3-Methylfentanyl chemical structure, C23H30N2O, CAS 42045-86-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
42045-86-3
Formula
C23H30N2O
Molar mass
350.51 g/mol
Melting point
-8 to 273.6 °C
HS code
293339
Category
Analgesics and anti-inflammatories

What is 3-Methylfentanyl?

Plain description, key identifiers and synonyms

3-methylfentanyl is the monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of 3-methyl-N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid. It has a role as an opioid analgesic, a sedative and a mu-opioid receptor agonist. It is an anilide, a member of piperidines, a monocarboxylic acid amide and a tertiary amino compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[3-methyl-1-(2-phenylethyl)piperidin-4-yl]-N-phenylpropanamide
CAS number
42045-86-3 CAS number cross-checked
Molecular formula
C23H30N2O
UNII
QVU94XE61A
InChIKey
MLQRZXNZHAOCHQ-UHFFFAOYSA-N
InChI
InChI=1S/C23H30N2O/c1-3-23(26)25(21-12-8-5-9-13-21)22-15-17-24(18-19(22)2)16-14-20-10-6-4-7-11-20/h4-13,19,22H,3,14-18H2,1-2H3
SMILES (canonical and isomeric)
CCC(=O)N(C1CCN(CC1C)CCC2=CC=CC=C2)C3=CC=CC=C3

Synonyms

  • Mefentanyl
  • 3-Methylfentanil
  • DEA No. 9813
  • N-(3-Methyl-1-(2-phenylethyl)-4-piperidinyl)-N-phenylpropanamide
  • Propanamide, N-(3-methyl-1-(2-phenylethyl)-4-piperidinyl)-N-phenyl-
  • N-[3-methyl-1-(2-phenylethyl)piperidin-4-yl]-N-phenylpropanamide
  • 3-methyl-fentanyl
  • N-(3-methyl-1-(2-phenylethyl)piperidin-4-yl)-N-phenylpropanamide
  • IDS-NM-017(SECT.3)
  • China White
  • Discontinued see: M205505
  • N-(3-Methyl-1-(2-phenylethyl)-4-piperidyl)-N-phenylpropanamide
  • US20230399418, Compound 3-Methylfentanyl
  • N-(3-Methyl-1-phenethyl-4-piperidyl)propionanilide
  • N-(3-methyl-1-phenethyl-4-piperidyl)-N-phenylpropanamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Melting point
-8 to 273.6 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
350.51 g/molcalc.
Exact mass
350.2358 Dacalc.
LogP (octanol/water)
4.38calc.
Topological polar surface area
23.55 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
6calc.
Heavy atoms
26calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.44calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(CCN2CCC(Nc3ccccc3)CC2)cc1

c1ccc(CCN2CCC(Nc3ccccc3)CC2)cc1

3 rings, 21 atoms, the N-Phenyl-1-(2-phenylethyl)-4-piperidinamine ring system.

368 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

3-Methylfentanyl suppliers

Trading restrictions apply to this substance

Narcotic drug

3-Methylfentanyl is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Single Convention on Narcotic Drugs 1961

Our policy on controlled substances

3-Methylfentanyl price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

3-Methylfentanyl (DEA Code Number: 9813) is a Schedule I controlled substance.

Schedule I Controlled Substance: (A) The drug or other substance has a high potential for abuse, (B) The drug or other substance has no currently accepted medical use in treatment in the United States, and (C) There is a lack of accepted safety for use of the drug or other substance under medical supervision.

Analgesics.

Pharmacological actions

  • Analgesics

Roles

  • agonist
  • analgesic
  • central nervous system depressant
  • central nervous system drug
  • mu-opioid agent
  • mu-opioid receptor agonist
  • neurotransmitter agent
  • opioid agent
  • opioid analgesic
  • opioid receptor agonist
  • pharmaceutical
  • sedative

Functional uses

  • Pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

Narcotic drug

3-Methylfentanyl is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Single Convention on Narcotic Drugs 1961

Our policy on controlled substances

Controls

  • US DEA controlled substance or listed chemical
  • Controlled narcotic drug

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 3-Methylfentanyl is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 3-Methylfentanyl is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 3-Methylfentanyl, based on the data on this page

What is 3-Methylfentanyl?

3-methylfentanyl is the monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of 3-methyl-N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid. It has a role as an opioid analgesic, a sedative and a mu-opioid receptor agonist.

What is the CAS number of 3-Methylfentanyl?

The CAS registry number of 3-Methylfentanyl is 42045-86-3.

What is the molecular formula and weight of 3-Methylfentanyl?

The molecular formula of 3-Methylfentanyl is C23H30N2O and its molar mass is 350.51 g/mol.

What is 3-Methylfentanyl used for?

3-Methylfentanyl (DEA Code Number: 9813) is a Schedule I controlled substance. Schedule I Controlled Substance: (A) The drug or other substance has a high potential for abuse, (B) The drug or other substance has no currently accepted medical use in treatment in the United States, and (C) There is a lack of accepted sa…

Is 3-Methylfentanyl hazardous?

No GHS hazard classification for 3-Methylfentanyl is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of 3-Methylfentanyl?

3-Methylfentanyl is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Can I buy 3-Methylfentanyl on CompoundList?

No. 3-Methylfentanyl is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle 3-Methylfentanyl

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

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