CompoundList
Sign in
Amines and amides

6-Hydroxydopamine

Also known as oxidopamine, 5-(2-aminoethyl)benzene-1,2,4-triol, 2,4,5-Trihydroxyphenethylamine

CAS 1199-18-4Formula C8H11NO3Molar mass 169.18 g/molEC 214-842-3
8 suppliers listed
Get quotes Compare 8 suppliers
6-Hydroxydopamine chemical structure, C8H11NO3, CAS 1199-18-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
1199-18-4
Formula
C8H11NO3
Physical form
Solid
HS code
292229
Category
Amines and amides
UN number
UN 2811
Illustrative photo, closed blue fibre drums on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is 6-Hydroxydopamine?

Plain description, key identifiers and synonyms

Oxidopamine is a benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease). It has a role as a drug metabolite, a neurotoxin and a human metabolite. It is a benzenetriol, a catecholamine and a primary amino compound. It is functionally related to a dopamine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
5-(2-aminoethyl)benzene-1,2,4-triol
CAS number
1199-18-4 CAS number cross-checked
EC number
214-842-3
Molecular formula
C8H11NO3
UNII
8HW4YBZ748
InChIKey
DIVDFFZHCJEHGG-UHFFFAOYSA-N
InChI
InChI=1S/C8H11NO3/c9-2-1-5-3-7(11)8(12)4-6(5)10/h3-4,10-12H,1-2,9H2
SMILES (canonical and isomeric)
C1=C(C(=CC(=C1O)O)O)CCN

Synonyms

  • oxidopamine
  • 5-(2-aminoethyl)benzene-1,2,4-triol
  • 2,4,5-Trihydroxyphenethylamine
  • Oxidopamina
  • 6-OHDA
  • Oxidopaminum
  • 5-(2-Aminoethyl)-1,2,4-benzenetriol
  • 1,2,4-Benzenetriol, 5-(2-aminoethyl)-
  • 6 Hydroxydopamine
  • Hydrochloride, Oxidopamine
  • Topamine
  • 6-Hydroxy Dopamine hydrobromide
  • 6-hydroxy-dopamine
  • Oxidopamine (USAN/INN)
  • 4-13-00-02916 (Beilstein Handbook Reference)
  • DivK1c_000362
  • 5-(2-azanylethyl)benzene-1,2,4-triol, hydrobromide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Solidexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
169.18 g/molcalc.
Exact mass
169.0739 Dacalc.
LogP (octanol/water)
0.3calc.
Topological polar surface area
86.71 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
2calc.
Heavy atoms
12calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.25calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS classification
Hazard pictograms
UN number
UN 2811

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

6-Hydroxydopamine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 8 suppliers
8 of 8 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

8 suppliers in 3 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

6-Hydroxydopamine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Adrenergic Agents
  • Sympatholytics

Roles

  • aetiopathogenetic role
  • animal metabolite
  • drug metabolite
  • eukaryotic metabolite
  • human metabolite
  • human xenobiotic metabolite
  • mammalian metabolite
  • metabolite
  • neurotoxin
  • poison
  • xenobiotic metabolite

Pharmacology

Oxidopamine is an antagonist of the neurotransmitter dopamine with potential antineoplastic activity. 6-Hydroxydopamine (6-HOD) can be taken up by selective adrenergic terminals, thereby causing acute degeneration of adrenergic terminals that leads to depletion of norepinephrine, and of dopamine in the dopamine-sensitive sites. This agent is auto-oxidated at physiological pH that leads to the formation of reactive free radicals, thereby leading to cytotoxicity in neural cells. 6-Hydroxydopamine is often used to induce CNS and sympathetic neural lesions that model aging and various nervous disorders in animal systems.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 6-Hydroxydopamine is traded under.

HS 2922.29Indicative HS code

Amino-naphthols and other amino-phenols, other than those containing more than one kind…

World exports in 2024
$467M
−15.3% vs 2023, imports $454M
2019 to 2024
Top exporters
  1. China63.1%
  2. India * partner reported15.5%
  3. Japan4.0%
Top importers
  1. India * partner reported25.8%
  2. United States14.4%
  3. South Korea7.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 6-Hydroxydopamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 6-Hydroxydopamine, based on the data on this page

What is 6-Hydroxydopamine?

Oxidopamine is a benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).

Guides for buyers

Practical guides that help when you source, ship or handle 6-Hydroxydopamine

Get quotes for 6-Hydroxydopamine

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell 6-Hydroxydopamine
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of 6-Hydroxydopamine with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/6-hydroxydopamine-1199-18-4" title="6-Hydroxydopamine structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Amines and amides or HS code 292229

8 suppliers
Free quotes, contact stays private
Get quotes