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Steroids and sterols

7alpha-Hydroxy-DHEA

Also known as 7alpha-Hydroxydehydroepiandrosterone, 7alpha-OH-DHEA, 7-Hydroxydehydroepiandrosterone

CAS 53-00-9Formula C19H28O3Molar mass 304.43 g/molEC 111-753-0
GHS signal word: Danger. Pictograms: Serious health hazard 3 suppliers listed
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7alpha-Hydroxy-DHEA chemical structure, C19H28O3, CAS 53-00-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
53-00-9
Formula
C19H28O3
Molar mass
304.43 g/mol
EC number
111-753-0
HS code
293723
Category
Steroids and sterols

What is 7alpha-Hydroxy-DHEA?

Plain description, key identifiers and synonyms

7alpha-hydroxydehydroepiandrosterone is an androstanoid that is dehydroepiandrosterone carrying an additional hydroxy substituent at the 7alpha-position. It has a role as an antioxidant, an estrogen, an anti-inflammatory agent, a human xenobiotic metabolite and a rat metabolite. It is a 3beta-hydroxy-Delta(5)-steroid, a 17-oxo steroid, a 7alpha-hydroxy steroid and an androstanoid. It is functionally related to a dehydroepiandrosterone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3S,7S,8R,9S,10R,13S,14S)-3,7-dihydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
CAS number
53-00-9 CAS number cross-checked
EC number
111-753-0
Molecular formula
C19H28O3
UNII
CL15H93XTM
InChIKey
OLPSAOWBSPXZEA-JIEICEMKSA-N
InChI
InChI=1S/C19H28O3/c1-18-7-5-12(20)9-11(18)10-15(21)17-13-3-4-16(22)19(13,2)8-6-14(17)18/h10,12-15,17,20-21H,3-9H2,1-2H3/t12-,13-,14-,15+,17-,18-,19-/m0/s1
Canonical SMILES
CC12CCC3C(C(O)C=C4CC(O)CCC43C)C1CCC2=O
Isomeric SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)[C@@H](C=C4[C@@]3(CC[C@@H](C4)O)C)O

Synonyms

  • 7alpha-Hydroxydehydroepiandrosterone
  • 7alpha-OH-DHEA
  • 7-Hydroxydehydroepiandrosterone
  • 3beta,7alpha-Dihydroxy-5-androstene-17-one
  • (3S,7S,8R,9S,10R,13S,14S)-3,7-dihydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
  • (3beta,7alpha)-3,7-dihydroxyandrost-5-en-17-one
  • Androst-5-en-17-one, 3,7-dihydroxy-, (3beta,7alpha)-
  • (3S,7S,8R,9S,10R,13S,14S)-3,7-dihydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta(a)phenanthren-17-one
  • 7-alpha-Hydroxydehydroepiandrosterone
  • 3beta,7alpha-dihydroxy-5-androsten-17-one
  • 7?-Hydroxy Dehydro Epiandrosterone
  • 3Beta,7alpha-dihydroxyandrost-5-en-17-one
  • 7|A-Hydroxy-DHEA
  • 7alpha-Hydroxy Dehydro Epiandrosterone (1mg/ml in Acetonitrile)
  • 7a-Hydroxydehydroepiandrosterone
  • (3aS,3bR,4S,7S,9aR,9bS,11aS)-4,7-dihydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-one
  • 7a-Hydroxy-DHEA
  • 7-alpha-OH-DHEA
  • 7-a-OH-DHEA
  • 7alpha-hydroxy-DHEA (7HD)
  • 7a-Hydroxydehydroisoandrosterone
  • 7??-hydroxy Dehydroepiandrosterone
  • (-)-7a-Hydroxydehydroepiandrosterone
  • 3b,7a-Dihydroxy-5-androsten-17-one
  • 3b,7a-Dihydroxy-5-androstene-17-one
Show all 31 synonyms
  • 3b,7a-dihydroxy-Androst-5-en-17-one
  • 7|A inverted exclamation mark-Hydroxy dhea
  • 3beta,7alpha-dihydroxy-androst-5-en-17-one
  • 7alpha-hydroxydehydroisoandrosterone
  • (3b,7a)-3,7-dihydroxy-Androst-5-en-17-one
  • (-)-7alpha-hydroxydehydroepiandrosterone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
304.43 g/molcalc.
Exact mass
304.2038 Dacalc.
LogP (octanol/water)
2.85calc.
Topological polar surface area
57.53 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
0calc.
Heavy atoms
22calc.
Rings
4calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.84calc.
Formal charge
0calc.
Stereocentres
7calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCC2C1CCC1C3CCCCC3=CCC21

O=C1CCC2C1CCC1C3CCCCC3=CCC21

4 rings, 18 atoms.

156 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H351Suspected of causing cancer.
  • H360FDMay damage fertility. May damage the unborn child.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

7alpha-Hydroxy-DHEA suppliers

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All 3 suppliers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

3 suppliers in 2 countries

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7alpha-Hydroxy-DHEA price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • agonist
  • animal metabolite
  • anti-inflammatory agent
  • antioxidant
  • estrogen
  • eukaryotic metabolite
  • hormone
  • human metabolite
  • human xenobiotic metabolite
  • mammalian metabolite
  • metabolite
  • molecular messenger
  • rat metabolite
  • sex hormone
  • xenobiotic metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 7alpha-Hydroxy-DHEA is traded under.

HS 2937.23Indicative HS code

Oestrogens and progestogens

World exports in 2024
$762M
−2.3% vs 2023, imports $693M
2019 to 2024
Top exporters
  1. China42.9%
  2. Italy18.4%
  3. Netherlands8.9%
Top importers
  1. India * partner reported12.1%
  2. United States11.0%
  3. Belgium8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 7alpha-Hydroxy-DHEA is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 7alpha-Hydroxy-DHEA, based on the data on this page

What is 7alpha-Hydroxy-DHEA?

7alpha-hydroxydehydroepiandrosterone is an androstanoid that is dehydroepiandrosterone carrying an additional hydroxy substituent at the 7alpha-position. It has a role as an antioxidant, an estrogen, an anti-inflammatory agent, a human xenobiotic metabolite and a rat metabolite.

What is the CAS number of 7alpha-Hydroxy-DHEA?

The CAS registry number of 7alpha-Hydroxy-DHEA is 53-00-9.

What is the molecular formula and weight of 7alpha-Hydroxy-DHEA?

The molecular formula of 7alpha-Hydroxy-DHEA is C19H28O3 and its molar mass is 304.43 g/mol.

What is 7alpha-Hydroxy-DHEA used for?

Known uses and roles of 7alpha-Hydroxy-DHEA include agonist, animal metabolite, anti-inflammatory agent, antioxidant, estrogen and 10 more.

Is 7alpha-Hydroxy-DHEA hazardous?

7alpha-Hydroxy-DHEA carries the GHS signal word "Danger". Main hazards: suspected of causing cancer, may damage fertility. may damage the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 7alpha-Hydroxy-DHEA?

7alpha-Hydroxy-DHEA is usually classified under HS code 293723 (Oestrogens and progestogens). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 7alpha-Hydroxy-DHEA?

CompoundList lists 3 suppliers of 7alpha-Hydroxy-DHEA in Czech Republic and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of 7alpha-Hydroxy-DHEA?

Suppliers quote 7alpha-Hydroxy-DHEA on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 7alpha-Hydroxy-DHEA

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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