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Peptides

Abarelix

Also known as Plenaxis, abarelixum, Abarelix Acetate

CAS 183552-38-7Formula C72H95ClN14O14Molar mass 1,416.09 g/mol
2 suppliers listed
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Abarelix chemical structure, C72H95ClN14O14, CAS 183552-38-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
183552-38-7
Formula
C72H95ClN14O14
Molar mass
1,416.09 g/mol
HS code
293339
Category
Peptides

What is Abarelix?

Plain description, key identifiers and synonyms

Abarelix is a polypeptide compound composed of ten natural and non-natural amino acid resiudes in a linear sequence. It has a role as an antineoplastic agent and a hormone antagonist.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]-methylamino]-3-(4-hydroxyphenyl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-[(2S)-2-[[(2R)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-6-(propan-2-ylamino)hexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]butanediamide
CAS number
183552-38-7 CAS number cross-checked
Molecular formula
C72H95ClN14O14
UNII
W486SJ5824
InChIKey
AIWRTTMUVOZGPW-HSPKUQOVSA-N
InChI
InChI=1S/C72H95ClN14O14/c1-41(2)32-54(64(93)80-53(17-10-11-30-77-42(3)4)72(101)87-31-13-18-60(87)69(98)78-43(5)63(75)92)81-68(97)58(38-62(74)91)84-70(99)61(37-46-22-27-52(90)28-23-46)86(7)71(100)59(40-88)85-67(96)57(36-48-14-12-29-76-39-48)83-66(95)56(34-45-20-25-51(73)26-21-45)82-65(94)55(79-44(6)89)35-47-19-24-49-15-8-9-16-50(49)33-47/h8-9,12,14-16,19-29,33,39,41-43,53-61,77,88,90H,10-11,13,17-18,30-32,34-38,40H2,1-7H3,(H2,74,91)(H2,75,92)(H,78,98)(H,79,89)(H,80,93)(H,81,97)(H,82,94)(H,83,95)(H,84,99)(H,85,96)/t43-,53+,54+,55-,56-,57-,58-,59+,60+,61+/m1/s1
Canonical SMILES
CC(=O)NC(Cc1ccc2ccccc2c1)C(=O)NC(Cc1ccc(Cl)cc1)C(=O)NC(Cc1cccnc1)C(=O)NC(CO)C(=O)N(C)C(Cc1ccc(O)cc1)C(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCCCNC(C)C)C(=O)N1CCCC1C(=O)NC(C)C(N)=O
Isomeric SMILES
C[C@H](C(=O)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCNC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(=O)N)NC(=O)[C@H](CC2=CC=C(C=C2)O)N(C)C(=O)[C@H](CO)NC(=O)[C@@H](CC3=CN=CC=C3)NC(=O)[C@@H](CC4=CC=C(C=C4)Cl)NC(=O)[C@@H](CC5=CC6=CC=CC=C6C=C5)NC(=O)C

Synonyms

  • Plenaxis
  • abarelixum
  • Abarelix Acetate
  • PPI 149
  • Plenaxis depot
  • Abarelix-Depot-M
  • Abarelix Trifluoroacetate Salt (~90%)
  • Plenaxis (TN)
  • Abarelix (USAN/INN)
  • C72H95ClN14O14
  • Abarelix acetate - Bio-X trade mark
  • Ac-D-Nal-[D-(pCl)Phe]-D-Pal-Ser-[Nalpha-Me-Tyr]-D-Asn-Leu-ILys-Pro-DAla-NH2

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
1,416.09 g/molcalc.
Exact mass
1,414.6841 Dacalc.
LogP (octanol/water)
1.17calc.
Topological polar surface area
425 Ųcalc.
Hydrogen bond donors
13calc.
Hydrogen bond acceptors
16calc.
Rotatable bonds
38calc.
Heavy atoms
101calc.
Rings
6calc.
Aromatic rings
5calc.
Fraction sp3 carbons
0.46calc.
Formal charge
0calc.
Stereocentres
10calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(CNC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C(Cc1cccnc1)NC(=O)C(Cc1ccccc1)NC(=O)CCc1ccc2ccccc2c1)NCC(=O)N1CCCC1

O=C(CNC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C(Cc1cccnc1)NC(=O)C(Cc1ccccc1)NC(=O)CCc1ccc2ccccc2c1)NCC(=O)N1CCCC1

6 rings, 68 atoms.

19 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Abarelix suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 2 suppliers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

2 suppliers in 1 country

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Abarelix price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Hormone Antagonists

Roles

  • antagonist
  • antineoplastic agent
  • hormone antagonist
  • hormone receptor modulator
  • pharmaceutical
  • receptor modulator

Pharmacology

Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Abarelix is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Abarelix is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Abarelix, based on the data on this page

What is Abarelix?

Abarelix is a polypeptide compound composed of ten natural and non-natural amino acid resiudes in a linear sequence. It has a role as an antineoplastic agent and a hormone antagonist.

What is the CAS number of Abarelix?

The CAS registry number of Abarelix is 183552-38-7.

What is the molecular formula and weight of Abarelix?

The molecular formula of Abarelix is C72H95ClN14O14 and its molar mass is 1,416.09 g/mol.

What is Abarelix used for?

Known uses and roles of Abarelix include antagonist, antineoplastic agent, hormone antagonist, hormone receptor modulator, pharmaceutical and 2 more.

Is Abarelix hazardous?

No GHS hazard classification for Abarelix is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Abarelix?

Abarelix is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Abarelix?

CompoundList lists 2 suppliers of Abarelix in China. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Abarelix?

Suppliers quote Abarelix on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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