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Cardiovascular and metabolic drugs

Acetohexamide

Also known as Dymelor, Acetohexamid, Dimelor

CAS 968-81-0Formula C15H20N2O4SMolar mass 324.40 g/molEC 213-530-4
24 suppliers listed
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Acetohexamide chemical structure, C15H20N2O4S, CAS 968-81-0
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals from 90% aq ethanol
Melting point
188 to 190
Solubility
PRACTICALLY INSOL IN WATER & ETHER, SLIGHTLY SOL IN ALCOHOL & CHLOROFORM, SOL IN PYRIDIN…
HS code
293590
Category
Cardiovascular and metabolic drugs
Illustrative photo, closed blue fibre drums on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Acetohexamide?

Plain description, key identifiers and synonyms

Acetohexamide is an N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is replaced by a p-acetylphenylsulfonyl group, while a hydrogen attached to the other nitrogen is replaced by a cyclohexyl group. It has a role as a hypoglycemic agent and an insulin secretagogue. It is a member of acetophenones and a N-sulfonylurea.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-(4-acetylphenyl)sulfonyl-3-cyclohexylurea
CAS number
968-81-0 CAS number cross-checked
EC number
213-530-4
Molecular formula
C15H20N2O4S
UNII
QGC8W08I6I
MDL number
MFCD00072156
InChIKey
VGZSUPCWNCWDAN-UHFFFAOYSA-N
InChI
InChI=1S/C15H20N2O4S/c1-11(18)12-7-9-14(10-8-12)22(20,21)17-15(19)16-13-5-3-2-4-6-13/h7-10,13H,2-6H2,1H3,(H2,16,17,19)
SMILES (canonical and isomeric)
CC(=O)C1=CC=C(C=C1)S(=O)(=O)NC(=O)NC2CCCCC2

Synonyms

  • Dymelor
  • Acetohexamid
  • Dimelor
  • Metaglucina
  • Tsiklamid
  • Minoral
  • Ordimel
  • Hypoglicil
  • Acetohexamida
  • Acetohexamidum
  • 4-Acetyl-N-[(cyclohexylamino)carbonyl]benzenesulfonamide
  • N-(p-Acetylphenylsulfonyl)-N'-cyclohexylurea
  • 1-((p-Acetylphenyl)sulfonyl)-3-cyclohexylurea
  • 1-(p-Acetylbenzenesulfonyl)-3-cyclohexylurea
  • 3-(4-acetylbenzenesulfonyl)-1-cyclohexylurea
  • 4-Acetyl-N-((cyclohexylamino)carbonyl)benzenesulfonamide
  • N-(p-Acetylbenzenesulfonyl)-N'-cyclohexylurea
  • Benzenesulfonamide, 4-acetyl-N-((cyclohexylamino)carbonyl)-
  • Benzenesulfonamide, 4-acetyl-N-[(cyclohexylamino)carbonyl]-
  • 1-[(p-Acetylphenyl)sulfonyl]-3-cyclohexylurea
  • Urea, 1-((p-acetylphenyl)sulfonyl)-3-cyclohexyl-
  • 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide
  • Urea, 1-[(p-acetylphenyl)sulfonyl]-3-cyclohexyl-
  • 1-((4-acetylbenzene)sulfonyl)-3-cyclohexylurea
  • 1-[(4-acetylbenzene)sulfonyl]-3-cyclohexylurea
Show all 35 synonyms
  • acetoesamide
  • 3-cyclohexyl-1-(p-acetylphenylsulfonyl)urea
  • Gamadiabet
  • Dimelin
  • 1-(4-acetylphenyl)sulfonyl-3-cyclohexylurea
  • Acetoexamide
  • Acetohexamide [USAN)
  • 4-acetyl-N-(cyclohexylcarbamoyl)benzene-1-sulfonamide
  • Dymelor (TN)
  • 1-(4-acetylphenyl)sulfonyl-3-cyclohexyl-urea

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from 90% aq ethanolexp.
Odour
PRACTICALLY ODORLESSexp.
Melting point
188 to 190exp.
Solubility
PRACTICALLY INSOL IN WATER & ETHER, SLIGHTLY SOL IN ALCOHOL & CHLOROFORM, SOL IN PYRIDINE & DILUTE SOLN OF ALKALI HYDROXIDESexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
324.40 g/molcalc.
Exact mass
324.1144 Dacalc.
LogP (octanol/water)
2.21calc.
Topological polar surface area
92.34 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
4calc.
Heavy atoms
22calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.47calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(NC1CCCCC1)NS(=O)(=O)c1ccccc1

O=C(NC1CCCCC1)NS(=O)(=O)c1ccccc1

2 rings, 19 atoms, the Benzenesulfonyl-N'-cyclohexylurea ring system.

23 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS classification
Hazard pictograms

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Acetohexamide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 24 suppliers
24 of 24 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

24 suppliers in 7 countries

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Acetohexamide price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Therapeutic category: Antidiabetic.

An orally effective hypoglycemic compound.

Use classes: Pharmaceuticals.

Industries and functions

Pharmacological actions

  • Hypoglycemic Agents

Roles

  • hypoglycemic agent
  • insulin secretagogue
  • ophthalmology drug
  • pharmaceutical
  • secretagogue

Pharmacology

Acetohexamide is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. Acetohexamide is metabolized in the liver to its active metabolite hydroxyhexamide.

How it is made

British patent 912,789 (1962 to Lilly), Marshall et al, J Med Chem 6, (1963).

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Inactive in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Acetohexamide is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Acetohexamide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Acetohexamide, based on the data on this page

What is Acetohexamide?

Acetohexamide is an N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is replaced by a p-acetylphenylsulfonyl group, while a hydrogen attached to the other nitrogen is replaced by a cyclohexyl group. It has a role as a hypoglycemic agent and an insulin secretagogue.

What is the CAS number of Acetohexamide?

The CAS registry number of Acetohexamide is 968-81-0.

What is the molecular formula and weight of Acetohexamide?

The molecular formula of Acetohexamide is C15H20N2O4S and its molar mass is 324.40 g/mol.

What is Acetohexamide used for?

Therapeutic category: Antidiabetic. An orally effective hypoglycemic compound. Use classes: Pharmaceuticals.

Is Acetohexamide hazardous?

No GHS hazard classification for Acetohexamide is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Acetohexamide?

Acetohexamide is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Acetohexamide?

CompoundList lists 24 suppliers of Acetohexamide in China, United States, Netherlands, France and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Acetohexamide in India?

1 supplier in India list Acetohexamide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Acetohexamide?

Suppliers quote Acetohexamide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Acetohexamide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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