Acetone
Also known as 2-propanone, propanone, propan-2-one
Key facts
What buyers check first
- Appearance
- Colorless volatile liquid
- Melting point
- -94.9 °C
- Boiling point
- 56.1 °C
- Density
- 0.7845 g/cm³ at 20 °C
- Flash point
- -17 °C
- HS code
- 291411
- Category
- Ketone and ester solvents
- UN number
- UN 1090
What is Acetone?
Plain description, key identifiers and synonyms
Acetone is a methyl ketone that consists of propane bearing an oxo group at C2. It has a role as a polar aprotic solvent, a human metabolite and an EC 3.5.1.4 (amidase) inhibitor. It is a volatile organic compound, a member of propanones, a methyl ketone and a ketone body.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- propan-2-one
- CAS number
- 67-64-1 CAS number cross-checked
- EC number
- 200-662-2
- Molecular formula
- C3H6O
- UNII
- 1364PS73AF
- MDL number
- MFCD00008765
- INCI name
- ACETONE
- InChIKey
- CSCPPACGZOOCGX-UHFFFAOYSA-N
- InChI
- InChI=1S/C3H6O/c1-3(2)4/h1-2H3
- SMILES (canonical and isomeric)
- CC(=O)C
Synonyms
- 2-propanone
- propanone
- propan-2-one
- Dimethyl ketone
- Pyroacetic ether
- Methyl ketone
- Dimethylformaldehyde
- beta-Ketopropane
- Dimethylketal
- Chevron acetone
- Ketone propane
- Aceton
- Pyroacetic acid
- Ketone, dimethyl
- Dimethyl formaldehyde
- RCRA waste number U002
- Taimax
- Acetone oil
- dimethylketone
- Ketone, dimethyl-
- Acetone-2-(1)(3)C
- (CH3)2CO
- Acetone (NF)
- Acetone (natural)
- Acetone, for HPLC, >=99.8%
Show all 35 synonymsShow fewer synonyms
- Acetone, for HPLC, >=99.9%
- Acetone, ACS reagent, >=99.5%
- Acetone (1,1,1,3,3,3-d6)
- RCRA waste no. U002
- dimethylcetone
- isopropanal
- methylketone
- Dimethylketon
- Propanon
- Sasetone
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Colorless volatile liquidexp.Measured value |
|---|---|
| Odour | Fruity odorexp.Measured value |
| Taste | Pungent, sweetishexp.Measured value |
| Melting point | -94.9 °Cexp.Measured value |
| Boiling point | 56.1 °Cexp.Measured value |
| Density | 0.7845 g/cm³ at 20 °Cexp.Measured value |
| Flash point | -17 °Cexp.Measured value |
| Autoignition temperature | 465 °Cexp.Measured value |
| Solubility | Miscible with waterexp.Measured value |
| Vapour pressure | 231 mm Hg at 25 °Cexp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 58.08 g/molcalc.Computed value |
|---|---|
| Exact mass | 58.0419 Dacalc.Computed value |
| LogP (octanol/water) | 0.6calc.Computed value |
| Topological polar surface area | 17.07 Ųcalc.Computed value |
| Hydrogen bond donors | 0calc.Computed value |
| Hydrogen bond acceptors | 1calc.Computed value |
| Rotatable bonds | 0calc.Computed value |
| Heavy atoms | 4calc.Computed value |
| Rings | 0calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.67calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H225Highly flammable liquid and vapour.
- H319Causes serious eye irritation.
- H336May cause drowsiness or dizziness.
Precautionary statements (20)
- P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P233Keep container tightly closed.
- P240Ground and bond container and receiving equipment.
- P241Use explosion-proof electrical, ventilating and lighting equipment.
- P242Use non-sparking tools.
- P243Take action to prevent static discharges.
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P271Use only outdoors or in a well-ventilated area.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P303 + P361 + P353If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P319Get medical help if you feel unwell.
- P337 + P317If eye irritation persists: Get medical help.
- P370 + P378In case of fire: Use appropriate media to extinguish.
- P403 + P233Store in a well-ventilated place. Keep container tightly closed.
- P403 + P235Store in a well-ventilated place. Keep cool.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
- UN number
- UN 1090
- Transport hazard class
- 3
- Packing group
- II
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidAcetone suppliers
Controlled substance, listings of documented suppliers only, in the documented ranking
Acetone is controlled. Only documented suppliers can list it, and buyers must upload a valid licence with their request. Every request is reviewed before suppliers see it.
Reference: UN Convention against Illicit Traffic 1988 Table II, India NDPS controlled substance, HS 2022 subheading 2914.11 (acetone)
Our policy on controlled substancesLicensed buyers can post a request for Acetone with their licence. Our compliance team reviews it before suppliers see it.
Acetone price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
The active ingredient is no longer contained in any registered (pesticide) products. ... "cancelled.".
Solvent for fats, oils, waxes, resins, rubber, plastics, lacquers, varnishes, rubber cements. Versatile reagent in organic synthesis. Manufacturing of coatings, plastics, pharmaceuticals and cosmetics. In production of other solvents and intermediates including: methyl isobutyl ketone, mesityl oxide, acetic acid (ketene process), diacetone alcohol, bisphenol A, methyl methacrylate, explosives, rayon, photographic films, isoprene.
In extraction of various principles from animal and plant substances, in paint & varnish removers, purifying paraffin, hardening and dehydrating tissues.
Industrial uses: Propellants, non-motive (blowing agents), Laboratory chemicals, Pigment, Etching agent, Intermediate, Sealant (barrier), Thickening agent.
Consumer uses: Flux agent, Absorbent, Cleaning agent, Sealant (barrier), Filler, Corrosion inhibitor, Chelating agent.
Use classes: Volatile organic compounds, Solvents, Specialized Industrial Chemicals, Safer Chemical Classes, Cosmetics.
Industries and functions
Cosmetic ingredient, INCI name ACETONE(denaturant, fragrance, solvent)
Pharmacological actions
- Solvents
Roles
- animal metabolite
- aprotic solvent
- enzyme inhibitor
- eukaryotic metabolite
- human metabolite
- mammalian metabolite
- metabolite
- polar aprotic solvent
- polar solvent
- solvent
Functional uses
- Adhesion/cohesion promoter
- Binder
- Cleaning agent
- Diluent
- Flavouring and nutrient
- Fragrance
- Solubility enhancer
- Solvent
Cosmetic functions
- Denaturant
- Fragrance
- Solvent
Pharmacology
Acetone is a colorless, volatile, flammable organic solvent. Acetone occurs naturally in plants, trees, forest fires, vehicle exhaust and as a breakdown product of animal fat metabolism. This agent may be normally present in very small quantities in urine and blood, larger amounts may be found in the urine and blood of diabetics. Acetone is toxic in high doses. (NCI04)
How it is made
Oxidation of cumene, dehydrogenation or oxidation of isopropyl alcohol with metallic catalyst, vapor-phase oxidation of butane, by-product of synthetic glycerol production.
The overall process for the production of acetone from benzene and propene consists of two major steps. In the first step cumene is produced from benzene and propene in the cumene process by Friedel-Crafts alkylation. Propane and other hydrocarbons contained in the propene feedstock are separated as low-boiling components in the cumene distillation unit.
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High-boiling components, mainly polyisopropylbenzenes, are separated as a residue. There is only a little amount of process water, which is generated from water dissolved in the benzene and propene feedstocks. In the second step (cumene oxidation, Hock process), cumene is first oxidized with atmospheric oxygen to cumene hydroperoxide (CHP). CHP is then cleaved to phenol and acetone by using a strong mineral acid as catalyst. Ketones, mainly byproducts from acetone, are separated as low-boiling components in the distillation. High-boiling components, which are mainly formed in the oxidation and cleavage unit, are separated as a residue. A certain amount of process water is generated in the phenol-acetone process and must be further treated in a biological wastewater treatment plant. The overall reaction can be considered as a dual oxidation: benzene is oxidized to phenol and propene is oxidized to acetone.
Regulatory status
Inventories, regulations and trade controls that list this substance
Acetone is controlled. Only documented suppliers can list it, and buyers must upload a valid licence with their request. Every request is reviewed before suppliers see it.
Reference: UN Convention against Illicit Traffic 1988 Table II, India NDPS controlled substance, HS 2022 subheading 2914.11 (acetone)
Our policy on controlled substancesEurope
- EU harmonised classification (CLP Annex VI)Index no: 606-001-00-8
Health and food
- EU cosmetic ingredient inventory
Controls
- US DEA controlled substance or listed chemical
- Drug precursor (UN 1988 Convention)
United States
- Safer Choice ingredient list (USA)
- TSCA inventory (USA)Status: Active in US commerce
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Acetone is traded under.
Ketones: acyclic, without other oxygen function, acetone
- Germany15.9%
- Thailand14.9%
- Netherlands10.4%
- China18.3%
- United States12.3%
- Germany9.7%
The HS code shown for Acetone is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.
Related chemicals
Parent and salt forms, stereoisomers, similar structures and isomers
Salt and hydrate forms
Records that share this compound as their parent
Stereoisomers and isotopic forms
Same connectivity, different stereochemistry or isotopes (same InChIKey skeleton)
Similar structures
Nearest neighbours by Morgan fingerprint Tanimoto similarity
Same formula isomers
Different compounds that share this molecular formula
Frequently asked questions
Quick answers about Acetone, based on the data on this page
What is Acetone?
What is the CAS number of Acetone?
What is the molecular formula and weight of Acetone?
What is Acetone used for?
Is Acetone hazardous?
What is the HS code of Acetone?
Can I buy Acetone on CompoundList?
Guides for buyers
Practical guides that help when you source, ship or handle Acetone
- Guide, Trade and logisticsShipping dangerous goods: UN numbers, classes and packing groupsHow the UN dangerous goods system works for chemicals, from the nine classes and UN numbers to packing groups, UN packaging marks, labels, documents and segregation.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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