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Pharmaceuticals and APIs

Acyclovir sodium

Also known as Aciclovir sodium, Acyclovir sodium salt, Sodium acyclovir

CAS 69657-51-8Formula C8H10N5NaO3Molar mass 247.19 g/molEC 614-996-5
GHS signal word: Warning. Pictograms: Harmful or irritant 55 suppliers listed Drug substance
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Acyclovir sodium chemical structure, C8H10N5NaO3, CAS 69657-51-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
69657-51-8
Formula
C8H10N5NaO3
Molar mass
247.19 g/mol
EC number
614-996-5
HS code
293359
Category
Pharmaceuticals and APIs

What is Acyclovir sodium?

Plain description, key identifiers and synonyms

Acyclovir Sodium is the sodium salt form of acyclovir, a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family. After conversion in vivo to the active metabolite acyclovir triphosphate by viral thymidine kinase, acyclovir competitively inhibits viral DNA polymerase by incorporating into the growing viral DNA chain and terminating further polymerization.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
sodium 2-amino-9-(2-hydroxyethoxymethyl)purin-6-olate
CAS number
69657-51-8 CAS number cross-checked
EC number
614-996-5
Molecular formula
C8H10N5NaO3
UNII
927L42J563
MDL number
MFCD01694138
InChIKey
RMLUKZWYIKEASN-UHFFFAOYSA-M
InChI
InChI=1S/C8H11N5O3.Na/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14;/h3,14H,1-2,4H2,(H3,9,11,12,15);/q;+1/p-1
SMILES (canonical and isomeric)
C1=NC2=C(N1COCCO)N=C(N=C2[O-])N.[Na+]

Synonyms

  • Aciclovir sodium
  • Acyclovir sodium salt
  • Sodium acyclovir
  • BW-248U Sodium
  • Bw248u sodium
  • bw-248u-Sodium
  • 9-((2-Hydroxyethoxy)methyl)guanine monosodium salt
  • Acyclovir in sodium chloride 0.9% preservative free
  • Zovirax for Injection
  • 2-Amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6H-purin-6-one Momsodium Salt
  • BW 248U sodium
  • Acyclovirsodium
  • Sodium 2-amino-9-((2-hydroxyethoxy)methyl)-9H-purin-6-olate
  • 2-Amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6H-purin-6-one monosodium salt
  • C8H10N5NaO3
  • Aciclovir natrium
  • 6H-Purin-6-one, 2-amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-, monosodium salt
  • BW 248U
  • Zovirax Sterile Powder
  • sodium 2-amino-9-[(2-hydroxyethoxy)methyl]-9H-purin-6-olate
  • Acycloguanosine sodium (Obs.)
  • sodium, 2-amino-9-(2-hydroxyethoxymethyl)purin-6-olate
  • Sodium 2-amino-9-[(2-hydroxyethoxy)methyl]purin-6-olate
  • &#60, p&#62, acyclovir sodium salt&#60, /p&#62,
  • Sodium2-amino-9-((2-hydroxyethoxy)methyl)-9H-purin-6-olate
Show all 27 synonyms
  • 6H-Purin-6-one, 1,9-dihydro-2-amino-9-((2-hydroxyethoxy)methyl)-, monosodium salt
  • Sodium 2-((4-(ethyl(3-sulfonatobenzyl)amino)phenyl)(4-(ethyl(3-sulfonatobenzy

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
247.19 g/molcalc.
Exact mass
247.0681 Dacalc.
LogP (octanol/water)
-4.55calc.
Topological polar surface area
122.1 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
7calc.
Rotatable bonds
4calc.
Heavy atoms
17calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.38calc.
Formal charge
0calc.
Stereocentres
0calc.
Components
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ncc2[nH]cnc2n1

c1ncc2[nH]cnc2n1

2 rings, 9 atoms, the Purine ring system.

2,038 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H317May cause an allergic skin reaction.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
  • H412Harmful to aquatic life with long lasting effects.
Precautionary statements (19)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Acyclovir sodium suppliers

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All 55 suppliers
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Where suppliers are based

55 suppliers in 13 countries

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Acyclovir sodium price

Indicative price range per kg from live supplier offers

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Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Roles

  • anti-HIV agent
  • anti-HSV agent
  • anti-obesity agent
  • antiinfective agent
  • antimicrobial agent
  • antineoplastic agent
  • antiviral agent
  • immunomodulator
  • immunosuppressive agent
  • ophthalmology drug
  • pharmaceutical
  • protective agent
  • renoprotective agent

Pharmacology

Acyclovir is an antiviral prescription medicine approved by the U.S. Food and Drug Administration (FDA) to:

Treat and/or prevent the recurrence of certain types of herpes simplex virus (HSV) infections, including genital herpes and herpes encephalitis

Treat varicella zoster virus (VZV) infections, including chicken pox (also called primary varicella infection) and shingles (also called herpes zoster)

Acyclovir is approved in different formulations and strengths for use in specific populations, including in people who are immunocompromised.

HSV and VZV infections can be opportunistic infections (OIs) of HIV.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Acyclovir sodium is traded under.

HS 2933.59Indicative HS code

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring, other

World exports in 2024
$18.4B
+10.5% vs 2023, imports $24.8B
2019 to 2024
Top exporters
  1. Ireland43.6%
  2. Switzerland * partner reported26.3%
  3. China7.9%
Top importers
  1. Slovenia30.3%
  2. United States30.1%
  3. Germany15.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Acyclovir sodium is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Acyclovir sodium, based on the data on this page

What is Acyclovir sodium?

Acyclovir Sodium is the sodium salt form of acyclovir, a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family.

What is the CAS number of Acyclovir sodium?

The CAS registry number of Acyclovir sodium is 69657-51-8.

What is the molecular formula and weight of Acyclovir sodium?

The molecular formula of Acyclovir sodium is C8H10N5NaO3 and its molar mass is 247.19 g/mol.

What is Acyclovir sodium used for?

Known uses and roles of Acyclovir sodium include anti-hiv agent, anti-hsv agent, anti-obesity agent, antiinfective agent, antimicrobial agent and 8 more.

Is Acyclovir sodium hazardous?

Acyclovir sodium carries the GHS signal word "Warning". Main hazards: causes skin irritation, may cause an allergic skin reaction, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Acyclovir sodium?

Acyclovir sodium is usually classified under HS code 293359 (Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Acyclovir sodium?

CompoundList lists 55 suppliers of Acyclovir sodium in United States, China, India, Germany and 9 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Acyclovir sodium in India?

4 suppliers in India list Acyclovir sodium on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Acyclovir sodium?

Suppliers quote Acyclovir sodium on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Acyclovir sodium

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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