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Heterocyclic building blocks

Altretamine

Also known as Hexamethylmelamine, Hexalen, Hexastat

CAS 645-05-6Formula C9H18N6Molar mass 210.29 g/molEC 211-428-4
GHS signal word: Warning. Pictograms: Harmful or irritant 51 suppliers listed
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Altretamine chemical structure, C9H18N6, CAS 645-05-6
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Needles from absolute ethanol
Melting point
172 to 174
Solubility
In water, 91 mg/L at 25 ยฐC
HS code
293369
Category
Heterocyclic building blocks
Illustrative photo, closed jumbo bulk bags in a warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Altretamine?

Plain description, key identifiers and synonyms

Hexamethylmelamine is a triamino-1,3,5-triazine.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine
CAS number
645-05-6 CAS number cross-checked
EC number
211-428-4
Molecular formula
C9H18N6
UNII
Q8BIH59O7H
MDL number
MFCD00549245
InChIKey
UUVWYPNAQBNQJQ-UHFFFAOYSA-N
InChI
InChI=1S/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H3
SMILES (canonical and isomeric)
CN(C)C1=NC(=NC(=N1)N(C)C)N(C)C

Synonyms

  • Hexamethylmelamine
  • Hexalen
  • Hexastat
  • Hemel
  • Altretamina
  • Melamine, hexamethyl-
  • Altretaminum
  • ENT 50852
  • 2,4,6-Tris(dimethylamino)-s-triazine
  • 2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine
  • s-Triazine, 2,4,6-tris(dimethylamino)-
  • 1,3,5-Triazine-2,4,6-triamine, N,N,N',N',N'',N''-hexamethyl-
  • Hexinawas
  • N,n,n',N\"N\"-hexamethyl-1,3,5,-triazine-2,4,6,-triamine
  • N,N,N',N',N\",N\"-hexamethyl-1,3,5-triazine-2,4,6-triamine
  • Hexamethylamine
  • 2,4,6-Tris(dimethylamino)-1,3,5-triazine
  • N2,N2,N4,N4,N6,N6-hexamethyl-1,3,5-triazine-2,4,6-triamine
  • NC 195
  • HMM
  • HTM
  • HXM
  • N,N,N',N',N'',N''-hexamethyl-1,3,5-triazine-2,4,6-triamine
  • Altretamine (Hexalen)
  • N~2~,N~2~,N~4~,N~4~,N~6~,N~6~-Hexamethyl-1,3,5-triazine-2,4,6-triamine
Show all 30 synonyms
  • ENT-50852, RB-1515, WR-95704
  • Hexalen (TN)
  • Hexalen [Antineoplastic]
  • Altretamine (USP/INN)
  • 645-05-6 (free base)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Needles from absolute ethanolexp.
Melting point
172 to 174exp.
Solubility
In water, 91 mg/L at 25 ยฐCexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
210.29 g/molcalc.
Exact mass
210.1593 Dacalc.
LogP (octanol/water)
0.07calc.
Topological polar surface area
48.39 ร…ยฒcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
3calc.
Heavy atoms
15calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.67calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ncncn1

c1ncncn1

1 ring, 6 atoms, the 1,3,5-Triazine ring system.

1,908 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (19)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Altretamine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 51 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

51 suppliers in 12 countries

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Altretamine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Single agent palliative treatment of patients with persistent or recurrent ovarian cancer following first-line therapy with a cisplatin and/or alkylating agent based combination.

Experimental insect chemosterilant.

Therapeutic category: Antineoplastic.

Pharmacological actions

  • Antineoplastic Agents, Alkylating

Roles

  • antineoplastic agent
  • pharmaceutical

Pharmacology

Altretamine is an Alkylating Drug. The mechanism of action of altretamine is as an Alkylating Activity.

How it is made

Production process: H. von Brachel, H. Kindler, DE 1240870, eidem, US 3424752 (1967, 1969 both to Casella Farbwerke)

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Altretamine is traded under.

HS 2933.69Indicative HS code

Compounds containing an unfused triazine ring (whether or not hydrogenated) in theโ€ฆ

World exports in 2024
$2.46B
+1.8% vs 2023, imports $2.44B
2019 to 2024
Top exporters
  1. China53.6%
  2. Germany11.5%
  3. India * partner reported8.4%
Top importers
  1. United States13.5%
  2. Brazil9.6%
  3. Germany9.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Altretamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Altretamine, based on the data on this page

What is Altretamine?

Hexamethylmelamine is a triamino-1,3,5-triazine.

What is the CAS number of Altretamine?

The CAS registry number of Altretamine is 645-05-6.

What is the molecular formula and weight of Altretamine?

The molecular formula of Altretamine is C9H18N6 and its molar mass is 210.29 g/mol.

What is Altretamine used for?

Single agent palliative treatment of patients with persistent or recurrent ovarian cancer following first-line therapy with a cisplatin and/or alkylating agent based combination. Experimental insect chemosterilant. Therapeutic category: Antineoplastic.

Is Altretamine hazardous?

Altretamine carries the GHS signal word "Warning". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Altretamine?

Altretamine is usually classified under HS code 293369 (Compounds containing an unfused triazine ring (whether or not hydrogenated) in theโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Altretamine?

CompoundList lists 51 suppliers of Altretamine in China, United States, India, United Kingdom and 8 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Altretamine in India?

3 suppliers in India list Altretamine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Altretamine?

Suppliers quote Altretamine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Altretamine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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