CompoundList
Subcategory of Building blocks and research compounds

Heterocyclic building blocks

Pyridines, pyrimidines, indoles, azoles, piperidines, morpholines and other heterocycles for discovery chemistry.
Chemicals
231.9K
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4,750
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About heterocyclic building blocks

Heterocyclic building blocks are ring compounds containing nitrogen, oxygen or sulfur that carry functional groups ready for further chemistry. The group covers substituted pyridines, pyrimidines, pyrazines and pyridazines, azoles such as pyrazoles, imidazoles, triazoles, oxazoles and thiazoles, indoles, indazoles, benzimidazoles and quinolines, saturated rings such as piperidines, piperazines, morpholines, pyrrolidines, azetidines and oxetanes, and spirocyclic and bridged scaffolds.

Read more about heterocyclic building blocks

Most marketed drugs contain at least one heterocycle, so medicinal chemists buy these building blocks constantly. Halogenated heterocycles serve as partners in cross-coupling, amino and carboxylic acid heterocycles join molecules by amide bonds, and saturated heterocycles add three-dimensional shape and improve solubility.

Ask for purity by NMR and LC-MS, regioisomeric purity, salt form (many amines are supplied as hydrochlorides), water content and storage conditions. Boc-protected amines are common for stability. For scale-up, check the route, because cheap routes may leave regioisomers that are hard to remove later. Heterocyclic compounds fall under HS headings 2932 to 2934.

Top heterocyclic building blocks

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Frequently asked questions

Quick answers about buying heterocyclic building blocks on CompoundList.

What are heterocyclic building blocks?

Pyridines, pyrimidines, indoles, azoles, piperidines, morpholines and other heterocycles for discovery chemistry.

How many heterocyclic building blocks are listed on CompoundList?

CompoundList lists 231,936 chemicals in heterocyclic building blocks. 4,750 suppliers offer products in this category.

Which heterocyclic building blocks are the most popular?

The most searched and traded heterocyclic building blocks on CompoundList include Histamine, Cyclophosphamide monohydrate, Omeprazole, (-)-Nicotine hydrogen (+)-tartrate and 5-Bromo-2'-deoxyuridine. They are part of the wider building blocks and research compounds family.

How do I buy heterocyclic building blocks in bulk?

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