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Cardiovascular and metabolic drugs

Amiodarone

Also known as Amiodarona, Amiodaronum, 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran

CAS 1951-25-3Formula C25H29I2NO3Molar mass 645.32 g/molEC 217-772-1
96 suppliers listed Drug substance
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Amiodarone chemical structure, C25H29I2NO3, CAS 1951-25-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
1951-25-3
Formula
C25H29I2NO3
Molar mass
645.32 g/mol
EC number
217-772-1
HS code
293299
Category
Cardiovascular and metabolic drugs

What is Amiodarone?

Plain description, key identifiers and synonyms

Amiodarone is a member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias. It has a role as a cardiovascular drug. It is an organoiodine compound, a member of 1-benzofurans, a tertiary amino compound and an aromatic ketone.

Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of irregular heartbeats.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone
CAS number
1951-25-3 CAS number cross-checked
EC number
217-772-1
Molecular formula
C25H29I2NO3
UNII
N3RQ532IUT
MDL number
MFCD00242801
InChIKey
IYIKLHRQXLHMJQ-UHFFFAOYSA-N
InChI
InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3
SMILES (canonical and isomeric)
CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I

Synonyms

  • Amiodarona
  • Amiodaronum
  • 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran
  • 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran
  • 2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone
  • Atlansil
  • (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone
  • Methanone, (2-butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)-
  • Methanone, (2-butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]-
  • Kordaron
  • {2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl}diethylamine
  • Amiodarex
  • 2-Butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone
  • (2-(4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy)ethyl)diethylamine
  • (2-butyl-1-benzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)methanone
  • (2-butyl-1-benzofuran-3-yl)-(4-(2-diethylaminoethoxy)-3,5-diiodophenyl)methanone
  • (2-butyl-1-benzofuran-3-yl)-[4-(2-diethylaminoethoxy)-3,5-diiodophenyl]methanone
  • SKF 33134A
  • Hydrochloride, Amiodarone
  • Cordarone
  • Cordarone (Salt/Mix)
  • CRD - Cardiac mixture
  • (2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone
  • (2-Butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)methanone
  • 2-Butyl-3-benzofuranyl p-((2-diethylamino)ethoxy)-m,m-diiodophenyl ketone
Show all 34 synonyms
  • Amjodaronum
  • 5-18-02-00353 (Beilstein Handbook Reference)
  • Ketone, 2-butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl
  • (2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}ethyl)diethylamine
  • Amidorone
  • Amiodarone Base
  • Amiodarone (USAN/INN)
  • AmiodaroneHCl
  • 2-Butyl-3-(3,5-diiodo-4-(beta-diethylaminoethoxy)benzoyl)benzofuran

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
645.32 g/molcalc.
Exact mass
645.0237 Dacalc.
LogP (octanol/water)
6.94calc.
Topological polar surface area
42.68 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
11calc.
Heavy atoms
31calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.4calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(c1ccccc1)c1coc2ccccc12

O=C(c1ccccc1)c1coc2ccccc12

3 rings, 17 atoms.

225 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Amiodarone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 96 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

96 suppliers in 18 countries

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Amiodarone price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Anti-Arrhythmia Agents
  • Cytochrome P-450 CYP1A2 Inhibitors
  • Cytochrome P-450 CYP2C9 Inhibitors
  • Cytochrome P-450 CYP2D6 Inhibitors
  • Cytochrome P-450 CYP3A Inhibitors
  • Potassium Channel Blockers
  • Sodium Channel Blockers
  • Vasodilator Agents

Roles

  • anti-arrhythmia drug
  • antimicrobial agent
  • antiviral agent
  • cardiovascular drug
  • pharmaceutical

Pharmacology

Amiodarone is an Antiarrhythmic. The mechanism of action of amiodarone is as a Cytochrome P450 3A Inhibitor, and P-Glycoprotein Inhibitor, and Cytochrome P450 1A2 Inhibitor, and Cytochrome P450 2C9 Inhibitor, and Cytochrome P450 2D6 Inhibitor.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Amiodarone is traded under.

HS 2932.99Indicative HS code

Heterocyclic compounds with oxygen hetero-atom(s) only, other

World exports in 2024
$3.81B
+10.3% vs 2023, imports $7.05B
2019 to 2024
Top exporters
  1. China28.9%
  2. Switzerland * partner reported12.7%
  3. Germany7.8%
Top importers
  1. United States49.7%
  2. China11.9%
  3. India * partner reported3.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Amiodarone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Amiodarone, based on the data on this page

What is Amiodarone?

Amiodarone is a member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias. It has a role as a cardiovascular drug.

What is the CAS number of Amiodarone?

The CAS registry number of Amiodarone is 1951-25-3.

What is the molecular formula and weight of Amiodarone?

The molecular formula of Amiodarone is C25H29I2NO3 and its molar mass is 645.32 g/mol.

What is Amiodarone used for?

Use classes: Pharmaceuticals.

Is Amiodarone hazardous?

No GHS hazard classification for Amiodarone is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Amiodarone?

Amiodarone is usually classified under HS code 293299 (Heterocyclic compounds with oxygen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Amiodarone?

CompoundList lists 96 suppliers of Amiodarone in United States, India, China, Germany and 14 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Amiodarone in India?

20 suppliers in India list Amiodarone on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Amiodarone?

Suppliers quote Amiodarone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Amiodarone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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