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Central nervous system drugs

Amphetamine

Also known as Amfetamine, 1-phenylpropan-2-amine, dl-Amphetamine

CAS 300-62-9Formula C9H13NMolar mass 135.21 g/molEC 200-458-3
GHS signal word: Danger. Pictograms: Flammable, Acute toxicity (severe) Prohibited, not for trade Drug substance
Why it is not for trade
Amphetamine chemical structure, C9H13N, CAS 300-62-9
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Mobile liquid
Boiling point
200 to 203
Density
0.936 g/cm³ at 25 °C
Flash point
100 °C
Solubility
Sparingly soluble in water (1:50)
HS code
292146
Category
Central nervous system drugs
UN number
UN 2811

What is Amphetamine?

Plain description, key identifiers and synonyms

1-phenylpropan-2-amine is a primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-phenylpropan-2-amine
CAS number
300-62-9 CAS number cross-checkedOther or deprecated CAS: 51-64-9, 60-15-1
EC numbers
200-458-3, 206-096-2
Molecular formula
C9H13N
UNII
CK833KGX7E
InChIKey
KWTSXDURSIMDCE-UHFFFAOYSA-N
InChI
InChI=1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3
SMILES (canonical and isomeric)
CC(CC1=CC=CC=C1)N

Synonyms

  • Amfetamine
  • 1-phenylpropan-2-amine
  • dl-Amphetamine
  • 1-Phenyl-2-aminopropane
  • Desoxynorephedrine
  • Norephedrane
  • Elastonon
  • Fenopromin
  • Phenedrine
  • beta-Aminopropylbenzene
  • Propisamine
  • Psychedrine
  • Raphetamine
  • Rhinalator
  • Simpatedrin
  • Sympatedrine
  • Actedron
  • Allodene
  • Anorexide
  • Anorexine
  • Benzebar
  • Benzolone
  • Isoamyne
  • Mecodrin
  • Novydrine
Show all 39 synonyms
  • Oktedrin
  • Ortedrine
  • Percomon
  • Profamina
  • Simpatina
  • Sympamine
  • Weckamine
  • Adipan
  • Finam
  • Isomyn
  • 1-Methyl-2-phenylethylamine
  • 1-Phenyl-2-propylamine
  • amfetaminum
  • alpha-Methylbenzeneethaneamine

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Mobile liquidexp.
Odour
Amine odorexp.
Taste
Acrid, burning tasteexp.
Boiling point
200 to 203exp.
Density
0.936 g/cm³ at 25 °Cexp.
Flash point
100 °Cexp.
Solubility
Sparingly soluble in water (1:50)exp.
Vapour pressure
0.24 Torr /mm Hg/ at 20 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
135.21 g/molcalc.
Exact mass
135.1048 Dacalc.
LogP (octanol/water)
1.58calc.
Topological polar surface area
26.02 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
2calc.
Heavy atoms
10calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.33calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS02: Flammable
Flammable
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H226Flammable liquid and vapour.
  • H300Fatal if swallowed.
Precautionary statements (17)
  • P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P233Keep container tightly closed.
  • P240Ground and bond container and receiving equipment.
  • P241Use explosion-proof electrical, ventilating and lighting equipment.
  • P242Use non-sparking tools.
  • P243Take action to prevent static discharges.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P303 + P361 + P353If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P370 + P378In case of fire: Use appropriate media to extinguish.
  • P403 + P235Store in a well-ventilated place. Keep cool.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.
UN number
UN 2811

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Amphetamine suppliers

Trading restrictions apply to this substance

Psychotropic substance

Amphetamine is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2921.46 (amfetamine and related stimulants)

Our policy on controlled substances

Amphetamine price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Veterinary medication:.

Amphetamine, its salts, optical isomers, and salts of its optical isomers (DEA Code Number: 1100) are Schedule II controlled substances. (Amphetamine, its salts, optical isomers, and salts of its optical isomers).

Schedule II Controlled Substance: (A) The drug or other substance has a high potential for abuse, (B) The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions, and (C) Abuse of the drug or other substances may lead to severe psychological or physical dependence.

Use classes: Anaesthetics, Pharmaceuticals.

Industries and functions

Pharmacological actions

  • Adrenergic Agents
  • Adrenergic Uptake Inhibitors
  • Central Nervous System Stimulants
  • Dopamine Agents
  • Dopamine Uptake Inhibitors
  • Sympathomimetics

Roles

  • adrenergic agent
  • adrenergic uptake inhibitor
  • aetiopathogenetic role
  • bronchodilator agent
  • dopamine uptake inhibitor
  • dopaminergic agent
  • environmental contaminant
  • neurotoxin
  • neurotransmitter agent
  • pharmaceutical
  • poison
  • sympathomimetic agent
  • xenobiotic

Functional uses

  • Pharmaceutical

Pharmacology

Amphetamine is a Central Nervous System Stimulant. The physiologic effect of amphetamine is by means of Central Nervous System Stimulation.

How it is made

Amphetamine is prepared by treating phenylacetone with formic acid and ammonia under the Leuckart-Wallach conditions.

Preparation: Goggin, USA patent 2507468 (1950 to Clarke & Clarke) (Amphetamine phosphate)

Preparation: ... F. P. Nabenhauer, USA patent 1921424 (1933 to SK & F).

Regulatory status

Inventories, regulations and trade controls that list this substance

Psychotropic substance

Amphetamine is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2921.46 (amfetamine and related stimulants)

Our policy on controlled substances

Health and food

  • EU Cosmetics Regulation Annex II, prohibited in cosmetics
    Name: Sympathicomimetic amines acting on the central nervous system: any substance contained in the first list of medicaments which are subject to medical pres…
  • Active ingredient in FDA approved drug labels

Controls

  • Controlled psychotropic substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Amphetamine is traded under.

HS 2921.46Exact HS code

Amfetamine (INN), benzfetamine (INN), dexamfetamine (INN), etilamfetamine (INN)…

World exports in 2024
$17.7M
−13.9% vs 2023, imports $15.8M
2019 to 2024
Top exporters
  1. Germany37.3%
  2. United States27.5%
  3. Denmark25.4%
Top importers
  1. United States26.3%
  2. Germany18.0%
  3. Australia16.2%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Amphetamine is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Amphetamine, based on the data on this page

What is Amphetamine?

1-phenylpropan-2-amine is a primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.

What is the CAS number of Amphetamine?

The CAS registry number of Amphetamine is 300-62-9. Other or deprecated CAS numbers: 51-64-9, 60-15-1.

What is the molecular formula and weight of Amphetamine?

The molecular formula of Amphetamine is C9H13N and its molar mass is 135.21 g/mol.

What is Amphetamine used for?

Veterinary medication:. Amphetamine, its salts, optical isomers, and salts of its optical isomers (DEA Code Number: 1100) are Schedule II controlled substances. (Amphetamine, its salts, optical isomers, and salts of its optical isomers).

Is Amphetamine hazardous?

Amphetamine carries the GHS signal word "Danger". Main hazards: flammable liquid and vapour, fatal if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Amphetamine?

Amphetamine is usually classified under HS code 292146 (Amfetamine (INN), benzfetamine (INN), dexamfetamine (INN), etilamfetamine (INN)…). This is indicative, confirm it with your customs broker before shipping.

Can I buy Amphetamine on CompoundList?

No. Amphetamine is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Amphetamine

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

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