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Central nervous system drugs

Dextroamphetamine

Also known as D-Amphetamine, Dexamphetamine, Dexamfetamine

CAS 51-64-9Formula C9H13NMolar mass 135.21 g/molEC 200-112-1
GHS signal word: Danger. Pictograms: Flammable, Corrosive, Acute toxicity (severe) Prohibited, not for trade Drug substance
Why it is not for trade
Dextroamphetamine chemical structure, C9H13N, CAS 51-64-9
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless liquid
Melting point
27.5 °C
Boiling point
203.5 °C
Density
0.949 g/cm³ at 15 °C
Solubility
Slightly soluble in water
HS code
292146
Category
Central nervous system drugs

What is Dextroamphetamine?

Plain description, key identifiers and synonyms

(S)-amphetamine is a 1-phenylpropan-2-amine that has S configuration. It has a role as a sympathomimetic agent, an adrenergic uptake inhibitor, an adrenergic agent, a dopaminergic agent, a neurotoxin and a dopamine uptake inhibitor. It is an enantiomer of a (R)-amphetamine.

Dextroamphetamine is a pharmaceutical drug.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S)-1-phenylpropan-2-amine
CAS number
51-64-9 CAS number cross-checked
EC number
200-112-1
Molecular formula
C9H13N
UNII
TZ47U051FI
InChIKey
KWTSXDURSIMDCE-QMMMGPOBSA-N
InChI
InChI=1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3/t8-/m0/s1
Canonical SMILES
CC(N)Cc1ccccc1
Isomeric SMILES
C[C@@H](CC1=CC=CC=C1)N

Synonyms

  • D-Amphetamine
  • Dexamphetamine
  • Dexamfetamine
  • (S)-Amphetamine
  • Dexadrine
  • (2S)-1-phenylpropan-2-amine
  • (+)-Amphetamine
  • (+)-(S)-Amphetamine
  • Dexidrine
  • (S)-(+)-Amphetamine
  • (S)-1-Phenyl-2-aminopropane
  • Amsustain
  • Dephadren
  • Sympamin
  • (S)-1-Phenyl-2-propylamine
  • (+)-alpha-Methylphenethylamine
  • (+)-alpha-Methylphenylethylamine
  • (S)-(+)-beta-Phenylisopropylamine
  • (S)-alpha-Phenylethylamine
  • D-alpha-methylphenethylamine
  • D-1-Phenyl-2-aminopropane
  • D-2-Amino-1-phenylpropane
  • (S)-alpha-methylbenzeneethanamine
  • dextro-Amphetamine
  • D-1-Phenyl-2-aminopropan
Show all 38 synonyms
  • Amphetamine, d-
  • (alphaS)-alpha-methylbenzeneethanamine
  • Amfetamine, (s)-
  • Xelstrym
  • Benzeneethanamine, alpha-methyl-, (S)-
  • dextro Amphetamine
  • 4-12-00-02587 (Beilstein Handbook Reference)
  • d Amphetamine
  • d Amphetamine Sulfate
  • Sulfate, Dextroamphetamine
  • Dextro Amphetamine Sulfate
  • alpha-Methylphenethylamine, d-
  • (+)-Phenaminum

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless liquidexp.
Melting point
27.5 °Cexp.
Boiling point
203.5 °Cexp.
Density
0.949 g/cm³ at 15 °Cexp.
Solubility
Slightly soluble in waterexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
135.21 g/molcalc.
Exact mass
135.1048 Dacalc.
LogP (octanol/water)
1.58calc.
Topological polar surface area
26.02 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
2calc.
Heavy atoms
10calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.33calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS02: Flammable
Flammable
GHS05: Corrosive
Corrosive
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H226Flammable liquid and vapour.
  • H300Fatal if swallowed.
  • H314Causes severe skin burns and eye damage.
Precautionary statements (24)
  • P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P233Keep container tightly closed.
  • P240Ground and bond container and receiving equipment.
  • P241Use explosion-proof electrical, ventilating and lighting equipment.
  • P242Use non-sparking tools.
  • P243Take action to prevent static discharges.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P301 + P330 + P331If swallowed: Rinse mouth. Do not induce vomiting.
  • P302 + P361 + P354If on skin: Take off immediately all contaminated clothing. Immediately rinse with water for several minutes.
  • P303 + P361 + P353If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P354 + P338If in eyes: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P316Get emergency medical help immediately.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P363Wash contaminated clothing before reuse.
  • P370 + P378In case of fire: Use appropriate media to extinguish.
  • P403 + P235Store in a well-ventilated place. Keep cool.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Dextroamphetamine suppliers

Trading restrictions apply to this substance

Psychotropic substance

Dextroamphetamine is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2921.46 (amfetamine and related stimulants)

Our policy on controlled substances

Dextroamphetamine price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Amphetamine, its salts, optical isomers, and salts of its optical isomers (DEA Code Number: 1100) are Schedule II controlled substances. (Amphetamine, its salts, optical isomers, and salts of its optical isomers).

Schedule II Controlled Substance: (A) The drug or other substance has a high potential for abuse, (B) The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions, and (C) Abuse of the drug or other substances may lead to severe psychological or physical dependence.

Veterinary medication:.

Central Nervous System Stimulants, Dopamine Uptake Inhibitors.

Industries and functions

Pharmacological actions

  • Central Nervous System Stimulants
  • Dopamine Uptake Inhibitors

Roles

  • adrenergic agent
  • adrenergic uptake inhibitor
  • aetiopathogenetic role
  • antidepressant
  • antineoplastic agent
  • antipsychotic agent
  • central nervous system depressant
  • central nervous system drug
  • dopamine uptake inhibitor
  • dopaminergic agent
  • immunomodulator
  • immunosuppressive agent
  • neurotoxin
  • neurotransmitter agent
  • pharmaceutical
  • poison
  • psychotropic drug
  • sympathomimetic agent
  • tranquilizing drug

Pharmacology

Dextroamphetamine is a Central Nervous System Stimulant. The physiologic effect of dextroamphetamine is by means of Central Nervous System Stimulation.

How it is made

By resolving dl-amphetamine bitartrate, liberating and extracting the d-amphetamine component, and neutralizing the d-amphetamine with an equimolar portion of phosphoric acid, by using suitable solvents, the neutralization reaction may be conducted so as to cause precipitation of the crystalline salt as it is formed. (Dextroamphetamine phosphate)

This compound can be prepared by optical resolution of amphetamine or directly from (-)-norephedrine by conversion to the (+)-chloramine followed by catalytic hydrogenation.

Preparation by resolution of amphetamine: Temmler, United Kingdom patent 508757 (1939), Nabenhauer, USA patent 2276508 (1942 to SK&F).

Regulatory status

Inventories, regulations and trade controls that list this substance

Psychotropic substance

Dextroamphetamine is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2921.46 (amfetamine and related stimulants)

Our policy on controlled substances

Health and food

  • Active ingredient in FDA approved drug labels

Controls

  • Controlled psychotropic substance

United States

  • TSCA inventory (USA)
    Status: Inactive in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Dextroamphetamine is traded under.

HS 2921.46Exact HS code

Amfetamine (INN), benzfetamine (INN), dexamfetamine (INN), etilamfetamine (INN)…

World exports in 2024
$17.7M
−13.9% vs 2023, imports $15.8M
2019 to 2024
Top exporters
  1. Germany37.3%
  2. United States27.5%
  3. Denmark25.4%
Top importers
  1. United States26.3%
  2. Germany18.0%
  3. Australia16.2%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Dextroamphetamine is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Dextroamphetamine, based on the data on this page

What is Dextroamphetamine?

(S)-amphetamine is a 1-phenylpropan-2-amine that has S configuration. It has a role as a sympathomimetic agent, an adrenergic uptake inhibitor, an adrenergic agent, a dopaminergic agent, a neurotoxin and a dopamine uptake inhibitor. It is an enantiomer of a (R)-amphetamine.

What is the CAS number of Dextroamphetamine?

The CAS registry number of Dextroamphetamine is 51-64-9.

What is the molecular formula and weight of Dextroamphetamine?

The molecular formula of Dextroamphetamine is C9H13N and its molar mass is 135.21 g/mol.

What is Dextroamphetamine used for?

Amphetamine, its salts, optical isomers, and salts of its optical isomers (DEA Code Number: 1100) are Schedule II controlled substances. (Amphetamine, its salts, optical isomers, and salts of its optical isomers).

Is Dextroamphetamine hazardous?

Dextroamphetamine carries the GHS signal word "Danger". Main hazards: flammable liquid and vapour, fatal if swallowed, causes severe skin burns and eye damage. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Dextroamphetamine?

Dextroamphetamine is usually classified under HS code 292146 (Amfetamine (INN), benzfetamine (INN), dexamfetamine (INN), etilamfetamine (INN)…). This is indicative, confirm it with your customs broker before shipping.

Can I buy Dextroamphetamine on CompoundList?

No. Dextroamphetamine is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Dextroamphetamine

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

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