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Other active pharmaceutical ingredients

Anthralin

Also known as Dithranol, Cignolin, Chrysodermol

CAS 1143-38-0Formula C14H10O3Molar mass 226.23 g/molEC 214-538-0
GHS signal word: Warning. Pictograms: Harmful or irritant 89 suppliers listed Drug substance
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Anthralin chemical structure, C14H10O3, CAS 1143-38-0
2D chemical structure

Key facts

What buyers check first

All properties
Physical form
Crystals
Melting point
176.1 to 181.1
Solubility
Less than 1 mg/mL at 68 °F
HS code
291450
Category
Other active pharmaceutical ingredients
Illustrative photo, closed white HDPE bottles and amber jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Anthralin?

Plain description, key identifiers and synonyms

Anthralin is an anthracene compound derived by the substitution of -OH groups for hydrogen at C-1 and C-8, and with an oxo group at C-9. It has a role as an antipsoriatic. It is functionally related to an anthrone. It is a tautomer of an anthracene-1,8,9-triol.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1,8-dihydroxy-10H-anthracen-9-one
CAS number
1143-38-0 CAS number cross-checked
EC number
214-538-0
Molecular formula
C14H10O3
UNII
U8CJK0JH5M
MDL number
MFCD00053409
InChIKey
NUZWLKWWNNJHPT-UHFFFAOYSA-N
InChI
InChI=1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2
SMILES (canonical and isomeric)
C1C2=C(C(=CC=C2)O)C(=O)C3=C1C=CC=C3O

Synonyms

  • Dithranol
  • Cignolin
  • Chrysodermol
  • Cigthranol
  • 9(10H)-Anthracenone, 1,8-dihydroxy-
  • Batridol
  • 1,8-Dihydroxy-9-anthrone
  • Psoriacid-Stift
  • Anthra-Derm
  • Drithoscalp
  • Derobin
  • DrithoCreme
  • Lasan
  • Batidrol
  • Psodadrate
  • Psoriacide
  • Anthrone, 1,8-dihydroxy-
  • Dithranolum
  • Anthraderm
  • Dermaline
  • Zithranol-RR
  • 1,8-Dihydroxy-9(10H)-anthracenone
  • Anthralin (USP)
  • Ditranol
  • 1,8 Dihydroxy 9 anthrone
Show all 37 synonyms
  • Antraderm
  • Alphodith
  • Zithranol
  • Dithrocream fte
  • Dithrocream hp
  • Psorin fte
  • Stie-lasan
  • Dihydroxyanthranol
  • FNA, Ditranol
  • Dioxyanthranol
  • 1,8-Dihydroxyanthracen-9(10H)-one
  • 1,8-Dihydroxyanthrone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Crystalsexp.
Melting point
176.1 to 181.1exp.
Solubility
Less than 1 mg/mL at 68 °Fexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
226.23 g/molcalc.
Exact mass
226.063 Dacalc.
LogP (octanol/water)
2.23calc.
Topological polar surface area
57.53 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
0calc.
Heavy atoms
17calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.07calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1c2ccccc2Cc2ccccc21

O=C1c2ccccc2Cc2ccccc21

3 rings, 15 atoms, the Anthrone ring system.

128 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Anthralin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 89 suppliers
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Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

89 suppliers in 20 countries

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Anthralin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Dermatologic Agents

Roles

  • antipsoriatic
  • dermatologic drug
  • pharmaceutical

Pharmacology

Anthralin is a natural anthraquinone derivative, anti-psoriatic and anti-inflammatory Anthralin (dithranol) controls skin growth by reducing DNA synthesis and mitotic activity in the hyperplastic epidermis, restoring a normal rate of cell proliferation and keratinization. Used topically in the treatment of psoriasis, dermatoses, and alopecia areata, it is also used in biomedical research due to its effect on EGFR autophosphorylation. (NCI04)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Anthralin is traded under.

HS 2914.50Indicative HS code

Ketone-phenols and ketones with other oxygen function

World exports in 2024
$438M
+10.9% vs 2023, imports $420M
2019 to 2024
Top exporters
  1. China50.5%
  2. India * partner reported11.6%
  3. United States11.3%
Top importers
  1. United States20.8%
  2. Germany10.0%
  3. Netherlands8.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Anthralin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Anthralin, based on the data on this page

What is Anthralin?

Anthralin is an anthracene compound derived by the substitution of -OH groups for hydrogen at C-1 and C-8, and with an oxo group at C-9. It has a role as an antipsoriatic. It is functionally related to an anthrone. It is a tautomer of an anthracene-1,8,9-triol.

What is the CAS number of Anthralin?

The CAS registry number of Anthralin is 1143-38-0.

What is the molecular formula and weight of Anthralin?

The molecular formula of Anthralin is C14H10O3 and its molar mass is 226.23 g/mol.

What is Anthralin used for?

Known uses and roles of Anthralin include antipsoriatic, dermatologic drug, pharmaceutical and dermatologic agents.

Is Anthralin hazardous?

Anthralin carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Anthralin?

Anthralin is usually classified under HS code 291450 (Ketone-phenols and ketones with other oxygen function). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Anthralin?

CompoundList lists 89 suppliers of Anthralin in United States, China, United Kingdom, Germany and 16 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Anthralin in India?

2 suppliers in India list Anthralin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Anthralin?

Suppliers quote Anthralin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Anthralin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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