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Initiators, curing agents and crosslinkers

Artemether

Also known as beta-Artemether, Dihydroartemisinin methyl ether, Artemetero

CAS 71963-77-4Formula C16H26O5Molar mass 298.38 g/molEC 663-549-0
GHS signal word: Warning. Pictograms: Harmful or irritant 105 suppliers listed
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Artemether chemical structure, C16H26O5, CAS 71963-77-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
71963-77-4
Formula
C16H26O5
Appearance
Crystals
Melting point
86 to 88
HS code
293299
Category
Initiators, curing agents and crosslinkers
Illustrative photo, assorted laboratory chemical bottles and jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Artemether?

Plain description, key identifiers and synonyms

Artemether is an artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. It has a role as an antimalarial. It is an organic peroxide, a sesquiterpenoid, a cyclic acetal, an artemisinin derivative and a semisynthetic derivative.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
CAS number
71963-77-4 CAS number cross-checked
EC numbers
663-549-0, 695-829-3
Molecular formula
C16H26O5
UNII
C7D6T3H22J
MDL number
MFCD00866205
InChIKey
SXYIRMFQILZOAM-HVNFFKDJSA-N
InChI
InChI=1S/C16H26O5/c1-9-5-6-12-10(2)13(17-4)18-14-16(12)11(9)7-8-15(3,19-14)20-21-16/h9-14H,5-8H2,1-4H3/t9-,10-,11+,12+,13+,14-,15-,16-/m1/s1
Canonical SMILES
COC1OC2OC3(C)CCC4C(C)CCC(C1C)C24OO3
Isomeric SMILES
C[C@@H]1CC[C@H]2[C@H]([C@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC)C

Synonyms

  • beta-Artemether
  • Dihydroartemisinin methyl ether
  • Artemetero
  • Artemetherum
  • Artesaph
  • Falcidol
  • Malartem
  • Paluther
  • Gvither
  • Methyl-dihydroartemisinine
  • Artemisininelactol methyl ether
  • Artemetheri
  • Larither
  • Dihydroqinghaosu methyl ether
  • beta-Dihydroartemisinin methyl ether
  • SM 224
  • (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
  • O-Methyldihydroartemisinine
  • (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane
  • 10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane
  • beta Arthemeter
  • Coartem component artemether
  • alpha Artemether
  • (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo(10.3.1.0^(4,13).0^(8,13))hexadecane
  • (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo(10.3.1.04,13.08,13)hexadecane
Show all 35 synonyms
  • 10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo(10.3.1.04,13.08,13)hexadecane
  • 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-
  • 3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-
  • O Methyldihydroartemisinine
  • (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin
  • Artenam
  • (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
  • Artemos
  • methoxy(trimethyl)[?]
  • (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystalsexp.
Melting point
86 to 88exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
298.38 g/molcalc.
Exact mass
298.178 Dacalc.
LogP (octanol/water)
2.84calc.
Topological polar surface area
46.15 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
1calc.
Heavy atoms
21calc.
Rings
5calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
8calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CC2CCOC3OC4CCC(C1)C23OO4

C1CC2CCOC3OC4CCC(C1)C23OO4

5 rings, 16 atoms.

62 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
Precautionary statements (5)
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P301 + P317If swallowed: Get medical help.
  • P330Rinse mouth.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Artemether suppliers

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All 105 suppliers
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Where suppliers are based

105 suppliers in 14 countries

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Artemether price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Antimalarials

Roles

  • anti-HIV agent
  • antiinfective agent
  • antimalarial
  • antimicrobial agent
  • antimicrobial drug
  • antineoplastic agent
  • antiparasitic agent
  • antiplasmodial drug
  • antiprotozoal drug
  • antiviral agent
  • pharmaceutical

Pharmacology

Artemether is an Antimalarial.

How it is made

Prepn: Derivative of artemisinin. Y Li et al, Ko Hseuh Tung Pao 24: 667 (1979)

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Artemether is traded under.

HS 2932.99Indicative HS code

Heterocyclic compounds with oxygen hetero-atom(s) only, other

World exports in 2024
$3.81B
+10.3% vs 2023, imports $7.05B
2019 to 2024
Top exporters
  1. China28.9%
  2. Switzerland * partner reported12.7%
  3. Germany7.8%
Top importers
  1. United States49.7%
  2. China11.9%
  3. India * partner reported3.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Artemether is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Artemether, based on the data on this page

What is Artemether?

Artemether is an artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. It has a role as an antimalarial.

What is the CAS number of Artemether?

The CAS registry number of Artemether is 71963-77-4.

What is the molecular formula and weight of Artemether?

The molecular formula of Artemether is C16H26O5 and its molar mass is 298.38 g/mol.

What is Artemether used for?

Known uses and roles of Artemether include initiators and catalysts in plastics and polymers, curing agents and crosslinkers in plastics and polymers, anti-hiv agent, antiinfective agent, antimalarial and 9 more.

Is Artemether hazardous?

Artemether carries the GHS signal word "Warning". Main hazards: harmful if swallowed. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Artemether?

Artemether is usually classified under HS code 293299 (Heterocyclic compounds with oxygen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Artemether?

CompoundList lists 105 suppliers of Artemether in India, China, United States, Italy and 10 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Artemether in India?

50 suppliers in India list Artemether on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Artemether?

Suppliers quote Artemether on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Artemether

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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