Murcko scaffold
Ring system with 5 rings and 16 atoms
63 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 16
- Chemicals
- 63
- With full pages
- 24
Scaffold SMILES
C1CC2CCOC3OC4CCC(C1)C23OO4
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 63 chemicals
3-(3,6,9-Trimethyldecahydro-12H-3,12-epoxypyrano(4,3-j)(1,2)benzodioxepin-10-yl)propyl hydrogen carbonate
CAS 75918-39-7C19H30O7
beta-Artesunate
CAS 182824-33-5C19H28O8
Artemether
CAS 71963-77-4C16H26O5
Dihydroartemisinin ethyl ether
CAS 109716-83-8C17H28O5
9alpha-Hydroxyarteether
CAS 130855-38-8C17H28O6
alpha-Artemether
CAS 71939-51-0C16H26O5
Dihydroartemisinin
C15H24O5
rel-(3R,5aS,6R,8aS,9R,12R,12aR)-10-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin
CAS 131175-88-7C17H28O5
alpha-Arteether
CAS 82534-75-6C17H28O5
Npc182939
C15H24O5
![3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl- chemical structure, C17H28O5](/s/NLYNIRQVMRLPIQ-UHFFFAOYSA-N.svg)
3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-
C17H28O5
![3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, radical ion(1-), (3R,5aS,6R,8aS,9R,10S,12R,12aR)- chemical structure, C16H26O5, CAS 943595-08-2](/s/SXYIRMFQILZOAM-UHFFFAOYSA-N.svg)
3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, radical ion(1-), (3R,5aS,6R,8aS,9R,10S,12R,12aR)-
CAS 943595-08-2C16H26O5
3,6,9-Trimethyldecahydro-12H-3,12-epoxypyrano(4,3-j)(1,2)benzodioxepin-10-ol
CAS 98672-75-4C15H24O5
Arteether
CAS 75887-54-6C17H28O5
Artenimol
CAS 71939-50-9C15H24O5
alpha/beta-Arteether
CAS 123492-25-1C34H56O10
Arteannuin ether
CAS 80286-56-2C16H26O5
Artesunate
CAS 88495-63-0C19H28O8
Npc80142
CAS 131175-87-6C15H24O5
beta-Aminoarteether
CAS 133162-24-0C17H29NO5
![(1S,4S,5R,8S,9R,10S,12R,13R)-1,5,9-Trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecan-10-ol chemical structure, C15H24O5, CAS 1279039-00-7](/s/BJDCWCLMFKKGEE-CMDXXVQNSA-N.svg)
(1S,4S,5R,8S,9R,10S,12R,13R)-1,5,9-Trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecan-10-ol
CAS 1279039-00-7C15H24O5
![1-(((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-Trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)propan-2-one chemical structure, C18H28O6, CAS 133050-87-0](/s/DVMFSFNCNQUFDV-SRFZXGDHSA-N.svg)
1-(((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-Trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)propan-2-one
CAS 133050-87-0C18H28O6
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,9-dimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-6-methanol
CAS 174097-71-3C16H26O6
alpha-Dihydroartemisinin
CAS 81496-81-3C15H24O5
- Pharmakon1600-01504143C15H24O5
- 1 suppliers(1S,5R,9R,12R,13R)-1,5,9-Trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-olC15H24O5
- (3R,5aS,6R,8aS,9R,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin82638-05-9C16H26O5
- Alpha-propoxycarbonyldihydroartemisine71939-53-2C19H30O7
- 2-[(3R,5aS,6R,8aS,9R,10R,12R,12aR)-3,6,9-Trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl]acetaldehyde169174-16-7C17H26O5
- 3,12-Epoxy-12H-pyrano[3,4-j]-1,2-benzodioxepin-7-ol, 10-ethoxydecahydro-3,6,9-trimethyl-, [3R-(3I+/-,5aI(2),6I(2),7I(2),8aI(2),9I+/-,10I+/-,12I(2),12aR*)]-C17H28O6
- Artesunate and amodiaquine944945-14-6C39H50ClN3O9
- Sodium 4-oxo-4-[(3,6,9-trimethyldecahydro-12H-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10-yl)oxy]butanoate112419-28-0C19H27NaO8
- Butanedioic acid, 1-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester, compd. with 4-amino-N-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide and 5-(4-chlorophenyl)-6-ethyl-2,4-pyrimidinediamine (1:1:1)1232237-38-5C43H55ClN8O12S
- (5R,9R,12R,13R)-1,5,9-Trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-olC15H24O5
- 1 suppliersSodium artesunate82864-68-4C19H27NaO8
- Dihydroqinghaosu, dihydroartemisinin.C15H24O5
- 14-Hydroxyarteether130778-43-7C17H28O6
- Dihydro artemisinin-d3176774-98-4C15H24O5
- Artesunate and mefloquine497968-03-3C36H44F6N2O9
- Artemether-d393787-85-0C16H26O5
- alpha-Artemether-d393861-34-8C16H26O5
- Artesunate-d31316303-44-2C19H28O8
- Artesunate-d41316753-15-7C19H28O8
- 2-a-Hydroxyarteether130778-42-6C17H28O6
- (3R,5aS,6R,8aS,9S,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin162869-75-2C16H26O5
- (1S,4S,5R,8R,9R,10R,12R,13R)-1,5,9-Trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-olC15H24O5
- 2-((3R,5aS,6R,8aS,9R,10R,12R,12aR)-3,6,9-Trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)acetic Acid161562-97-6C17H26O6
- (1S,5R,9R,10R,12R)-1,5,9-Trimethyl-10-(trifluoromethyl)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-ol185418-56-8C16H23F3O5
Related scaffolds
Same ring framework with different atoms or bond orders
