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Antibiotics and anti-infectives

Azithromycin

Also known as Zithromax, Hemomycin, Azithromycine

CAS 83905-01-5Formula C38H72N2O12Molar mass 749.00 g/molEC 617-500-5
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard, Hazardous to the environment 230 suppliers listed Drug substance
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Azithromycin chemical structure, C38H72N2O12, CAS 83905-01-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
83905-01-5
Formula
C38H72N2O12
Appearance
Amorphous solid
Melting point
113 to 115
HS code
294150
Category
Antibiotics and anti-infectives
Illustrative photo, 25 kg white woven sacks of powder on a pallet in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Azithromycin?

Plain description, key identifiers and synonyms

Azithromycin is a macrolide antibiotic useful for the treatment of bacterial infections. It has a role as a xenobiotic, an antibacterial drug and an environmental contaminant. It is a conjugate base of an azithromycin(2+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
CAS number
83905-01-5 CAS number cross-checked
EC number
617-500-5
Molecular formula
C38H72N2O12
UNII
J2KLZ20U1M
MDL number
MFCD00873574
InChIKey
MQTOSJVFKKJCRP-BICOPXKESA-N
InChI
InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
Canonical SMILES
CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC2OC(C)CC(N(C)C)C2O)C(C)(O)CC(C)CN(C)C(C)C(O)C1(C)O
Isomeric SMILES
CC[C@@H]1[C@@]([C@@H]([C@H](N(C[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O

Synonyms

  • Zithromax
  • Hemomycin
  • Azithromycine
  • Azasite
  • Azithromycinum
  • Zitromax
  • Azenil
  • aziromycin
  • Azithrocin
  • Azitrocin
  • Macrozit
  • Azitromicina
  • Aruzilina
  • azithromycin anhydrous
  • Trozocina
  • Xithrone
  • Zithromac
  • Zythromax
  • Aziwin
  • DuraSite
  • CP 62993
  • Anhydrous azithromycin
  • Azyter
  • XZ 405
  • XZ 450
Show all 38 synonyms
  • Azithromycin (as dihydrate)
  • CP-62,993
  • Azadose
  • Ultreon
  • N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A
  • Dihydrate, Azithromycin
  • Clamelle
  • Sunamed
  • Monohydrate, Azithromycin
  • N-methyl-11-aza-10-deoxy-10-dihydroerythromycin A
  • Azythromycin
  • Sumamed
  • Zmax

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Amorphous solidexp.
Melting point
113 to 115exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
749.00 g/molcalc.
Exact mass
748.5085 Dacalc.
LogP (octanol/water)
1.9calc.
Topological polar surface area
180.1 Ųcalc.
Hydrogen bond donors
5calc.
Hydrogen bond acceptors
14calc.
Rotatable bonds
7calc.
Heavy atoms
52calc.
Rings
3calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.97calc.
Formal charge
0calc.
Stereocentres
18calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CC(OC2CCCCO2)CC(OC2CCCCO2)CCCCNCCCCO1

O=C1CC(OC2CCCCO2)CC(OC2CCCCO2)CCCCNCCCCO1

3 rings, 30 atoms.

45 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H317May cause an allergic skin reaction.
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H372Causes damage to organs through prolonged or repeated exposure.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (20)
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P272Contaminated work clothing should not be allowed out of the workplace.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P333 + P317If skin irritation or rash occurs: Get medical help.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403Store in a well-ventilated place.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Azithromycin suppliers

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All 230 suppliers
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Where suppliers are based

230 suppliers in 34 countries

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Azithromycin price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Anti-Bacterial Agents

Roles

  • analgesic
  • anti-HIV agent
  • anti-anaemic agent
  • anti-asthmatic agent
  • anti-inflammatory agent
  • anti-obesity agent
  • antibacterial agent
  • antibacterial drug
  • antifungal agent
  • antiinfective agent
  • antimalarial
  • antimicrobial agent
  • antineoplastic agent
  • antiparasitic agent
  • antitubercular agent
  • antitussive
  • antiviral agent
  • cardiovascular drug
  • environmental contaminant
  • gastrointestinal drug
  • immunomodulator
  • immunosuppressive agent
  • ophthalmology drug
  • xenobiotic

Pharmacology

Azithromycin is a Macrolide Antimicrobial. The chemical classification of azithromycin is Macrolides.

How it is made

Preparation: BE 892357, G. Kobrehel, S. Djokic, US 4517359 (1982, 1985 both to Sour Pliva), D.J.M. Allen, K.M. Nepveux, EP 298650, eidem, US 6268489 (1989, 2001 both to Pfizer)

Antibiotics are fermentation products and are isolated either as unfinished products or as intermediates, generally solid substances of limited stability. They are purified by methods normally employed in organic chemistry, which include chromatography, crystallization, and precipitation. (Antibiotics)

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Azithromycin is traded under.

HS 2941.50Indicative HS code

Erythromycin and its derivatives, salts thereof

World exports in 2024
$379M
−31.1% vs 2023, imports $408M
2019 to 2024
Top exporters
  1. China79.0%
  2. India * partner reported10.6%
  3. Malaysia1.7%
Top importers
  1. India * partner reported27.3%
  2. Japan9.9%
  3. Croatia6.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Azithromycin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Azithromycin, based on the data on this page

What is Azithromycin?

Azithromycin is a macrolide antibiotic useful for the treatment of bacterial infections. It has a role as a xenobiotic, an antibacterial drug and an environmental contaminant. It is a conjugate base of an azithromycin(2+).

What is the CAS number of Azithromycin?

The CAS registry number of Azithromycin is 83905-01-5.

What is the molecular formula and weight of Azithromycin?

The molecular formula of Azithromycin is C38H72N2O12 and its molar mass is 749.00 g/mol.

What is Azithromycin used for?

Use classes: Pharmaceuticals.

Is Azithromycin hazardous?

Azithromycin carries the GHS signal word "Danger". Main hazards: may cause an allergic skin reaction, may cause allergy or asthma symptoms or breathing difficulties if inhaled, causes damage to organs through prolonged or repeated exposure. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Azithromycin?

Azithromycin is usually classified under HS code 294150 (Erythromycin and its derivatives, salts thereof). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Azithromycin?

CompoundList lists 230 suppliers of Azithromycin in India, China, United States, Bangladesh and 30 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Azithromycin in India?

73 suppliers in India list Azithromycin on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Azithromycin?

Suppliers quote Azithromycin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Azithromycin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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