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beta-Carboline

Also known as 9H-Pyrido[3,4-B]indole, Norharman, Norharmane

beta-Carboline chemical structure, C11H8N2, CAS 244-63-3
2D chemical structure

Key facts

What buyers check first

CAS number
244-63-3
Formula
C11H8N2
Molar mass
168.20 g/mol
EC number
205-959-0
HS code
293979
Category
Alkaloids

What is beta-Carboline?

Plain description, key identifiers and synonyms

Beta-carboline is the parent compound of the beta-carbolines, a tricyclic structure comprising an indole ring system ortho- fused to C-3 and C-4 of a pyridine ring. It has a role as a marine metabolite and a fungal metabolite. It is a mancude organic heterotricyclic parent and a member of beta-carbolines.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
9H-pyrido[3,4-b]indole
CAS number
244-63-3 CAS number cross-checkedOther or deprecated CAS: 244-66-6
EC number
205-959-0
Molecular formula
C11H8N2
UNII
94HMA1I78O
MDL number
MFCD00004956
InChIKey
AIFRHYZBTHREPW-UHFFFAOYSA-N
InChI
InChI=1S/C11H8N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-7,13H
SMILES (canonical and isomeric)
C1=CC=C2C(=C1)C3=C(N2)C=NC=C3

Synonyms

  • 9H-Pyrido[3,4-B]indole
  • Norharman
  • Norharmane
  • Carbazoline
  • 2,9-Diazafluorene
  • 2-Azacarbazole
  • 9H-Pyrido(3,4-B)indole
  • norhormane
  • 2-hydroxy-1,3,5,6,11,11b-hexahydroindolizino(8,7-b)indole-2-carboxylic acid
  • 9H-Beta-carboline
  • 2H-Pyrido[3,4-b]indole
  • Nor Harmane
  • Carbazoline (VAN)
  • beta Carboline
  • Norharmane, 98%
  • Norharman - free base
  • 244-63-3 (Free base).
  • beta-carbol
  • 2-Carboline,
  • NRH
  • Norharman, free base
  • 2,9-Diazafluorene,
  • Norharmane (Standard)
  • 9H-Beta-carboline #
  • Norharmane, crystalline
Show all 32 synonyms
  • Kinome_3628
  • 9H-I(2)-Carboline
  • beta-carboline norharman
  • 5-23-08-00220 (Beilstein Handbook Reference)
  • Norharmane (9H-pyrido(3,4-b)indole
  • Sdccgmls-0003278.p003
  • 9H-Pyrido[3,4-b]indole, b-Carboline, 2,9-Diazafluorene

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
168.20 g/molcalc.
Exact mass
168.0687 Dacalc.
LogP (octanol/water)
2.72calc.
Topological polar surface area
28.68 ร…ยฒcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
0calc.
Heavy atoms
13calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)[nH]c1cnccc12

c1ccc2c(c1)[nH]c1cnccc12

3 rings, 13 atoms. This chemical is the scaffold itself.

374 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (19)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

beta-Carboline suppliers

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All 57 suppliers
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beta-Carboline price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Mutagens
  • Neurotoxins

Roles

  • eukaryotic metabolite
  • fungal metabolite
  • marine metabolite
  • metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code beta-Carboline is traded under.

HS 2939.79Indicative HS code

Alkaloids of vegetal origin, other than cocaine, ecgonine, salts, esters and other derivatives, not elsewhereโ€ฆ

World exports in 2024
$701M
+18.9% vs 2023, imports $830M
2019 to 2024
Top exporters
  1. Switzerland * partner reported25.3%
  2. Germany21.4%
  3. India * partner reported14.9%
Top importers
  1. United States20.9%
  2. Germany14.7%
  3. Italy14.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for beta-Carboline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about beta-Carboline, based on the data on this page

What is beta-Carboline?

Beta-carboline is the parent compound of the beta-carbolines, a tricyclic structure comprising an indole ring system ortho- fused to C-3 and C-4 of a pyridine ring. It has a role as a marine metabolite and a fungal metabolite. It is a mancude organic heterotricyclic parent and a member of beta-carbolines.

What is the CAS number of beta-Carboline?

The CAS registry number of beta-Carboline is 244-63-3. Other or deprecated CAS numbers: 244-66-6.

What is the molecular formula and weight of beta-Carboline?

The molecular formula of beta-Carboline is C11H8N2 and its molar mass is 168.20 g/mol.

What is beta-Carboline used for?

Known uses and roles of beta-Carboline include eukaryotic metabolite, fungal metabolite, marine metabolite, metabolite, mutagens and 1 more.

Is beta-Carboline hazardous?

beta-Carboline carries the GHS signal word "Warning". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of beta-Carboline?

beta-Carboline is usually classified under HS code 293979 (Alkaloids, natural or reproduced by synthesis, and their salts, ethers, esters and otherโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy beta-Carboline?

CompoundList lists 57 suppliers of beta-Carboline in China, United States, Germany, United Kingdom and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of beta-Carboline?

Suppliers quote beta-Carboline on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle beta-Carboline

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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